Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Case Report

Published on 15 Apr 2025

Case Report: Neoadjuvant therapy with ripretinib for gastrointestinal stromal tumor: a case report

in Pharmacology of Anti-Cancer Drugs

Guanmo Liu
Zicheng Zheng
Jie Li
Yixuan He
Chenggang Zhang
Yihua Wang
Weiming Kang
Xin Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573610

1,065 views

Original Research

Published on 15 Apr 2025

Integrative analysis of m6A-SNPs and single-cell RNA sequencing reveals key drivers of endocrine combined with CDK4/6 inhibitor therapy resistance in ER+ breast cancer

in Pharmacology of Anti-Cancer Drugs

Ruijie Ming
Han Zhang
Huan Wu
Fangbiao Zhan
Xiaoping Huang
Huawen Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590363

1,163 views

Original Research

Published on 14 Apr 2025

Dehydroleucodine exerts an antiproliferative effect on human Burkitt’s lymphoma Daudi cells via SLC7A11-mediated ferroptosis

in Pharmacology of Anti-Cancer Drugs

Rui Shen
Fang Cheng
Rui Guo
Wenjing Wang
Xiaolong Yang
Yemiao Chen
Yaokai Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572364

886 views

Case Report

Published on 14 Apr 2025

Case Report: A novel ELMOD3-ALK and EML4-ALK double-fusion responses to neoadjuvant alectinib in a lung adenocarcinoma patient

in Pharmacology of Anti-Cancer Drugs

Kaili Huang
Wen Li
Yinyin Xue
Lei Peng
Qiang Wu
Qinghua Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515826

947 views

Original Research

Published on 11 Apr 2025

Integrating multi-omics and experimental techniques to decode ubiquitinated protein modifications in hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Haikun Yang
Yuan Chen
Zheng Zhou
Yanjing Wang
Peng Li
Yang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545472

1,374 views

Original Research

Published on 11 Apr 2025

Elucidation of the mechanism Underlying the promotion of ferroptosis and enhanced antitumor immunity by citrus polymethoxyflavones in CRC cells

in Pharmacology of Anti-Cancer Drugs

Yingying Duan
Yu Wu
Jiaqi Tian
Yuqin Yin
Zhongwen Yuan
Wenting Zhu
Suyue Zhou
Chen Li
Senling Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571178

996 views

Original Research

Published on 10 Apr 2025

Pan-cancer analysis identified CD248 as a potential target for multiple tumor types

in Pharmacology of Anti-Cancer Drugs

Li Guo
Yan Liao
Xuyang Zhang
Rongjuan Guo
Zheng Wang
Deqin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554632

1,226 views

Original Research

Accepted on 09 Apr 2025

Synthesis, Anti-cancer Activity, and Mechanistic Insights of 2H-benzo[b][1,4]oxazin-3(4H)-one Linked 1,2,3-Triazoles in Human Cancer Cell Lines

in Pharmacology of Anti-Cancer Drugs

Qing-Ying Liu
Xixi Hou
Mingyue Tian
Baoyu He
Jingjing Guo
Yajie Guo
Jianxue Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565657

178 views

Original Research

Published on 09 Apr 2025

The biological function and prognostic significance of ferroptosis-related genes in clear cell renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Huizhen Ye
Xiwen Wu
Gehao Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515552

1,020 views

Review

Published on 08 Apr 2025

A novel perspective on bone tumors: advances in organoid research

in Pharmacology of Anti-Cancer Drugs

Zebing Ma
Yibing Liu
Rui Chen
Huayu Fan
Liang Kong
Xiangyang Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550163

1,055 views

Original Research

Published on 08 Apr 2025

MDM2 inhibitor induces apoptosis in colon cancer cells through activation of the CHOP-DR5 pathway, independent of p53 phenotype

in Pharmacology of Anti-Cancer Drugs

Manman Lu
Yingli Ren
Sijia Feng
Shenggen Wang
Weiyue Xia
Baoru Gu
Yuhou Shen
Aimin Yue
Na Li
Yongxi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508421

1,256 views

Original Research

Published on 07 Apr 2025

Miltirone enhances the chemosensitivity of gastric cancer cells to cisplatin by suppressing the PI3K/AKT signaling pathway

in Pharmacology of Anti-Cancer Drugs

Yiping Wang
Hang Lv
Li Shen
Zhe Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553791

1,163 views

Systematic Review

Published on 07 Apr 2025

A bibliometric and visual analysis based on immune checkpoint inhibitors for hepatocellular carcinoma: 2014 – 2024

in Pharmacology of Anti-Cancer Drugs

Gao-Min Liu
Rui Guo
Ji-Wei Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520055

1,133 views

Original Research

Published on 04 Apr 2025

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Gao-Sheng Yao
Jun-Shang Dai
Liang-Min Fu
Juan Lin
Zhi-Ping Tan
Lei Dai
Wei Chen
Jun-Hang Luo
Jin-Huan Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1470145

966 views

Original Research

Published on 04 Apr 2025

MicroRNA-665 and its potential role in drug response and survival outcomes in multiple myeloma: a preliminary study

in Pharmacology of Anti-Cancer Drugs

Rui Bergantim
Sara Peixoto da Silva
Vanessa Pinto
Joana M. Pereira
Diana Sousa
Fernanda Trigo
Rune Matthiesen
José E. Guimarães
M. Helena Vasconcelos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1465814

1,069 views

Original Research

Published on 03 Apr 2025

Norcantharidin inhibits TOP2A expression via H3K27me3 mediated epigenetic regulation to alleviate the progression of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Ruibing Wu
Hengye Yuan
Yuehua Wang
Xianggang Gou
Wanhua Hou
Zhongzheng Zhou
Xinran Wang
Xiuling Deng
Changshan Wang
Haisheng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541298

1,014 views