Frontiers in Pharmacology | Pharmacology of Ion Channels and Channelopathies

Original Research

Published on 19 Feb 2024

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

in Pharmacology of Ion Channels and Channelopathies

Guiying Cui
Kerry M. Strickland
Analia J. Vazquez Cegla
Nael A. McCarty

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1363456

2,304 views

Review

Published on 15 Feb 2024

Application of calcium overload-based ion interference therapy in tumor treatment: strategies, outcomes, and prospects

in Pharmacology of Ion Channels and Channelopathies

Shuangjiang Li
Ruicheng Fan
Yuekai Wang
Kunqian He
Jinhe Xu
Hongli Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352377

3,309 views
8 citations

Review

Published on 24 Jan 2024

A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel

in Pharmacology of Ion Channels and Channelopathies

Cesar A. Amaya-Rodriguez
Karina Carvajal-Zamorano
Daniel Bustos
Melissa Alegría-Arcos
Karen Castillo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1251061

6,951 views
6 citations

Mini Review

Published on 11 Jan 2024

Role of sodium leak channel (NALCN) in sensation and pain: an overview

in Pharmacology of Ion Channels and Channelopathies

Donghang Zhang
Yiyong Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1349438

4,347 views
4 citations

Brief Research Report

Published on 15 Dec 2023

Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds

in Pharmacology of Ion Channels and Channelopathies

Lucy O. Ojomoko
Elena V. Kryukova
Natalya S. Egorova
Arthur I. Salikhov
Lyubov A. Epifanova
Daria A. Denisova
Alex R. Khomutov
Dmitry A. Sukhov
Alexander A. Vassilevski
Maxim A. Khomutov

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1327603

2,274 views
2 citations

Original Research

Published on 11 Dec 2023

Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium

in Pharmacology of Ion Channels and Channelopathies

Miroslaw Zajac
Agathe Lepissier
Elise Dréano
Benoit Chevalier
Aurélie Hatton
Mairead Kelly-Aubert
Daniela Guidone
Gabrielle Planelles
Aleksander Edelman
Emmanuelle Girodon

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1293578

2,995 views
2 citations

Original Research

Published on 22 Nov 2023

Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy

in Pharmacology of Ion Channels and Channelopathies

Vera Paar
Michael Haslinger
Philipp Krombholz-Reindl
Stefan Pittner
Matthias Neuner
Peter Jirak
Tobias Kolbitsch
Bernd Minnich
Falk Schrödl
Alexandra Kaser-Eichberger

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1264216

3,717 views
1 citation

Review

Published on 14 Nov 2023

News and views on ion channels in cancer: is cancer a channelopathy?

in Pharmacology of Ion Channels and Channelopathies

Damian C. Bell
Luigi Leanza
Saverio Gentile
Daniel R. Sauter

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1258933

5,429 views
12 citations

Original Research

Published on 14 Nov 2023

Structural modeling of hERG channel–drug interactions using Rosetta

in Pharmacology of Ion Channels and Channelopathies

Aiyana M. Emigh Cortez
Kevin R. DeMarco
Kazuharu Furutani
Slava Bekker
Jon T. Sack
Heike Wulff
Colleen E. Clancy
Igor Vorobyov
Vladimir Yarov-Yarovoy

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1244166

3,422 views
3 citations

Editorial

Published on 14 Nov 2023

Editorial: Real-world experience with CFTR modulator therapy

in Pharmacology of Ion Channels and Channelopathies

Burkhard Tümmler
Pierre-Régis Burgel

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1331829

1,416 views

Mini Review

Published on 07 Nov 2023

Vesicular CLC chloride/proton exchangers in health and diseases

in Pharmacology of Ion Channels and Channelopathies

Alessandra Picollo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1295068

1,658 views
3 citations

Original Research

Published on 25 Oct 2023

Dynamics of abdominal symptoms during the start of a new therapy with elexacaftor/tezacaftor/ivacaftor using the novel CFAbd-day2day questionnaire

in Pharmacology of Ion Channels and Channelopathies

Jochen G. Mainz
Anton Barucha
Pu Huang
Lilith Bechinger
Franziska Duckstein
Louise Polte
Pauline Sadrieh
Lutz Nährlich
Olaf Eickmeier
Suzanne Van Dullemen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1167407

2,059 views
5 citations

Review

Published on 24 Oct 2023

Ion channels in lung cancer: biological and clinical relevance

in Pharmacology of Ion Channels and Channelopathies

Chiara Capitani
Ginevra Chioccioli Altadonna
Michele Santillo
Elena Lastraioli

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1283623

3,362 views
2 citations

Original Research

Published on 17 Oct 2023

N-terminal region is responsible for mHv1 channel activity in MDSCs

in Pharmacology of Ion Channels and Channelopathies

Antonio Peña-Pichicoi
Miguel Fernández
Nieves Navarro-Quezada
Juan J. Alvear-Arias
Christian A. Carrillo
Emerson M. Carmona
Jose Garate
Angelica M. Lopez-Rodriguez
Alan Neely
Erick O. Hernández-Ochoa

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1265130

2,253 views

Review

Published on 28 Sep 2023

A review of the pathophysiology and the role of ion channels on bronchial asthma

in Pharmacology of Ion Channels and Channelopathies

Indyra Alencar Duarte Figueiredo
Sarah Rebeca Dantas Ferreira
Jayne Muniz Fernandes
Bagnólia Araújo da Silva
Luiz Henrique César Vasconcelos
Fabiana de Andrade Cavalcante

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1236550

13,521 views
11 citations

Original Research

Published on 12 Sep 2023

Cardiac safety assessment of a novel recombinant bispecific antibody targeting the ether-à-go-go related gene 1 (hERG1)-β1 integrin macromolecular complex

in Pharmacology of Ion Channels and Channelopathies

Lorenzo Santini
Claudia Duranti
Chiara Palandri
Lucrezia Giammarino
Monica Musumeci
Lucia Carlucci
Chiara Capitani
Rossella Colasurdo
Fabio Recchia
Elisabetta Cerbai

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1237431

2,086 views
5 citations