Frontiers in Pharmacology | Pharmacology of Ion Channels and Channelopathies

Review

Published on 22 Mar 2024

Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease

in Pharmacology of Ion Channels and Channelopathies

Felipe Echeverría
Naileth Gonzalez-Sanabria
Rosangelina Alvarado-Sanchez
Miguel Fernández
Karen Castillo
Ramon Latorre

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1373507

7,790 views
22 citations

Original Research

Published on 07 Mar 2024

CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells

in Pharmacology of Ion Channels and Channelopathies

Sven Kappel
Korollus Melek
Daniela Ross-Kaschitza
Barbara Hauert
Christian E. Gerber
Martin Lochner
Christine Peinelt

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1369513

3,022 views
3 citations

Original Research

Published on 19 Feb 2024

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

in Pharmacology of Ion Channels and Channelopathies

Guiying Cui
Kerry M. Strickland
Analia J. Vazquez Cegla
Nael A. McCarty

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1363456

2,897 views

Review

Published on 15 Feb 2024

Application of calcium overload-based ion interference therapy in tumor treatment: strategies, outcomes, and prospects

in Pharmacology of Ion Channels and Channelopathies

Shuangjiang Li
Ruicheng Fan
Yuekai Wang
Kunqian He
Jinhe Xu
Hongli Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352377

4,242 views
11 citations

Review

Published on 24 Jan 2024

A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel

in Pharmacology of Ion Channels and Channelopathies

Cesar A. Amaya-Rodriguez
Karina Carvajal-Zamorano
Daniel Bustos
Melissa Alegría-Arcos
Karen Castillo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1251061

9,614 views
11 citations

Mini Review

Published on 11 Jan 2024

Role of sodium leak channel (NALCN) in sensation and pain: an overview

in Pharmacology of Ion Channels and Channelopathies

Donghang Zhang
Yiyong Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1349438

5,377 views
5 citations

Brief Research Report

Published on 15 Dec 2023

Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds

in Pharmacology of Ion Channels and Channelopathies

Lucy O. Ojomoko
Elena V. Kryukova
Natalya S. Egorova
Arthur I. Salikhov
Lyubov A. Epifanova
Daria A. Denisova
Alex R. Khomutov
Dmitry A. Sukhov
Alexander A. Vassilevski
Maxim A. Khomutov

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1327603

2,795 views
2 citations

Original Research

Published on 11 Dec 2023

Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium

in Pharmacology of Ion Channels and Channelopathies

Miroslaw Zajac
Agathe Lepissier
Elise Dréano
Benoit Chevalier
Aurélie Hatton
Mairead Kelly-Aubert
Daniela Guidone
Gabrielle Planelles
Aleksander Edelman
Emmanuelle Girodon

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1293578

3,442 views
2 citations

Original Research

Published on 22 Nov 2023

Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy

in Pharmacology of Ion Channels and Channelopathies

Vera Paar
Michael Haslinger
Philipp Krombholz-Reindl
Stefan Pittner
Matthias Neuner
Peter Jirak
Tobias Kolbitsch
Bernd Minnich
Falk Schrödl
Alexandra Kaser-Eichberger

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1264216

4,691 views
4 citations

Review

Published on 14 Nov 2023

News and views on ion channels in cancer: is cancer a channelopathy?

in Pharmacology of Ion Channels and Channelopathies

Damian C. Bell
Luigi Leanza
Saverio Gentile
Daniel R. Sauter

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1258933

6,624 views
12 citations

Original Research

Published on 14 Nov 2023

Structural modeling of hERG channel–drug interactions using Rosetta

in Pharmacology of Ion Channels and Channelopathies

Aiyana M. Emigh Cortez
Kevin R. DeMarco
Kazuharu Furutani
Slava Bekker
Jon T. Sack
Heike Wulff
Colleen E. Clancy
Igor Vorobyov
Vladimir Yarov-Yarovoy

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1244166

4,319 views
4 citations

Editorial

Published on 14 Nov 2023

Editorial: Real-world experience with CFTR modulator therapy

in Pharmacology of Ion Channels and Channelopathies

Burkhard Tümmler
Pierre-Régis Burgel

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1331829

1,660 views

Mini Review

Published on 07 Nov 2023

Vesicular CLC chloride/proton exchangers in health and diseases

in Pharmacology of Ion Channels and Channelopathies

Alessandra Picollo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1295068

2,137 views
3 citations

Original Research

Published on 25 Oct 2023

Dynamics of abdominal symptoms during the start of a new therapy with elexacaftor/tezacaftor/ivacaftor using the novel CFAbd-day2day questionnaire

in Pharmacology of Ion Channels and Channelopathies

Jochen G. Mainz
Anton Barucha
Pu Huang
Lilith Bechinger
Franziska Duckstein
Louise Polte
Pauline Sadrieh
Lutz Nährlich
Olaf Eickmeier
Suzanne Van Dullemen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1167407

2,429 views
6 citations

Review

Published on 24 Oct 2023

Ion channels in lung cancer: biological and clinical relevance

in Pharmacology of Ion Channels and Channelopathies

Chiara Capitani
Ginevra Chioccioli Altadonna
Michele Santillo
Elena Lastraioli

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1283623

4,098 views
4 citations

Original Research

Published on 17 Oct 2023

N-terminal region is responsible for mHv1 channel activity in MDSCs

in Pharmacology of Ion Channels and Channelopathies

Antonio Peña-Pichicoi
Miguel Fernández
Nieves Navarro-Quezada
Juan J. Alvear-Arias
Christian A. Carrillo
Emerson M. Carmona
Jose Garate
Angelica M. Lopez-Rodriguez
Alan Neely
Erick O. Hernández-Ochoa

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1265130

2,618 views
1 citation