Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 30 Aug 2024

The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine

in Translational Pharmacology

Jennifer McDonough
Naveen K. Singhal
Paulina M. Getsy
Katherine Knies
Zackery T. Knauss
Devin Mueller
James N. Bates
Derek S. Damron
Stephen J. Lewis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1416701

1,986 views
2 citations

Review

Published on 28 Aug 2024

Advances in research on potential therapeutic approaches for Niemann-Pick C1 disease

in Translational Pharmacology

Caifeng Zhang
Keke Su
Xu Jiang
Yuping Tian
Ke Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465872

2,878 views
1 citation

Clinical Trial

Published on 22 Aug 2024

Pharmacokinetics and safety profiles of beinaglutide injection, a recombinant human GLP-1, in adults with overweight/obesity: results from a phase I clinical trial

in Translational Pharmacology

Pingping Lin
Chengqian Li
Yanping Liu
Feifei Sun
Tsung-Han Hsieh
Lin Zhang
Yaping Ma
Xiaomeng Gao
Qing Yu
Yu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433587

2,120 views
1 citation

Original Research

Published on 20 Aug 2024

In vitro evidence of antioxidant and anti-inflammatory effects of a new nutraceutical formulation explains benefits in a clinical setting of COPD patients

in Translational Pharmacology

Valentina Lazzara
Paola Pinto
Serena Di Vincenzo
Maria Ferraro
Filippo Catalano
Pietro Provinzano
Elisabetta Pace
Maria Rosaria Bonsignore

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439835

1,806 views
3 citations

Original Research

Published on 16 Aug 2024

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius

in Translational Pharmacology

Christian E. Edvardsson
Jesper Vestlund
Mia Ericson
Elisabet Jerlhag

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439203

2,440 views
3 citations

Original Research

Published on 12 Aug 2024

The integrated analysis of gut microbiota and metabolome revealed steroid hormone biosynthesis is a critical pathway in liver regeneration after 2/3 partial hepatectomy

in Translational Pharmacology

Runbin Sun
Fei Fei
Dandan Jin
Haoyi Yang
Zhi Xu
Bei Cao
Juan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407401

1,879 views
3 citations

Clinical Trial

Published on 12 Aug 2024

No QTc prolongation with CDK 4/6 inhibitor FCN-437c: results of a concentration-QTc analysis from a dedicated study in adult healthy subjects

in Translational Pharmacology

Lin Zhao
Yi Sun
Xiaoran Yang
Ling Tian
Lize Li
Fangfang Wang
Xiaoye Niu
Lei Diao
Haiyan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433663

1,820 views
1 citation

Review

Published on 05 Aug 2024

Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment

in Translational Pharmacology

Monika Chomczyk
Luca Gazzola
Shubhankar Dash
Patryk Firmanty
Binsah S. George
Vakul Mohanty
Hussein A. Abbas
Natalia Baran

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409210

4,324 views
2 citations

Perspective

Published on 02 Aug 2024

Artificial intelligence integration in the drug lifecycle and in regulatory science: policy implications, challenges and opportunities

in Translational Pharmacology

Wahiba Oualikene-Gonin
Marie-Christine Jaulent
Jean-Pierre Thierry
Sofia Oliveira-Martins
Laetitia Belgodère
Patrick Maison
Joël Ankri
The Scientific Advisory Board of ANSM

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437167

5,628 views
8 citations

Editorial

Published on 30 Jul 2024

Editorial: Pharmacoinformatics: new developments and challenges in drug design

in Translational Pharmacology

David Ramírez
Rafael Peláez
Carlos F. Lagos
José L. Medina-Franco

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462070

1,414 views

Original Research

Published on 30 Jul 2024

The 5HT4R agonist velusetrag efficacy on neuropathic chronic intestinal pseudo-obstruction in PrP-SCA7-92Q transgenic mice

in Translational Pharmacology

Yongqiang Liu
Yunfei Wu
Dewan Ren
Yulong Tao
Fangyi Mai
Jingyi Zhu
Xiang Li
Emanuela Colla
Maria Grimaldi
Roberto Giovannini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1411642

1,825 views
1 citation

Original Research

Published on 30 Jul 2024

Nanoparticles (NPs)-mediated lncMALAT1 silencing to reverse cisplatin resistance for effective hepatocellular carcinoma therapy

in Translational Pharmacology

Ting Wang
Qianyao Li
Rui Xu
Zixuan Zhao
Qi Sun
Xiaoding Xu
Rong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437071

1,966 views
4 citations

Original Research

Published on 29 Jul 2024

Causal gene identification using mitochondria-associated genome-wide mendelian randomization in atrial fibrillation

in Translational Pharmacology

Ying Chen
Bingxun Li
Hongxuan Xu
Lin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439816

2,766 views

Original Research

Published on 25 Jul 2024

When to consider intra-target microdosing: physiologically based pharmacokinetic modeling approach to quantitatively identify key factors for observing target engagement

in Translational Pharmacology

Yasunori Aoki
Malcom Rowland
Yuichi Sugiyama

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1366160

1,585 views

Review

Published on 25 Jul 2024

Ligand-conjugated multiwalled carbon nanotubes for cancer targeted drug delivery

in Translational Pharmacology

Chanchal Kiran Thakur
Chandrabose Karthikeyan
Charles R. Ashby
Rabin Neupane
Vishal Singh
R. Jayachandra Babu
N. S. Hari Narayana Moorthy
Amit K. Tiwari

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1417399

3,488 views
7 citations

Review

Published on 25 Jul 2024

Bibliometric and visualized analysis of ultrasound combined with microbubble therapy technology from 2009 to 2023

in Translational Pharmacology

Bin Tu
Yan Li
Wen Wen
Jian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1418142

1,990 views