Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 31 Oct 2022

Zebrafish as a platform to evaluate the potential of lipidic nanoemulsions for gene therapy in cancer

in Translational Pharmacology

María Cascallar
Pablo Hurtado
Saínza Lores
Alba Pensado-López
Ana Quelle-Regaldie
Laura Sánchez
Roberto Piñeiro
María de la Fuente

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1007018

3,558 views
5 citations

Review

Published on 28 Oct 2022

New insights into the characteristics of DRAK2 and its role in apoptosis: From molecular mechanisms to clinically applied potential

in Translational Pharmacology

Youwei Zheng
Xinchao Li
Lirun Kuang
Yong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1014508

6,087 views
6 citations

Original Research

Published on 25 Oct 2022

Circulating galectin-3 promotes tumor-endothelium-adhesion by upregulating ICAM-1 in endothelium-derived extracellular vesicles

in Translational Pharmacology

Lei Wang
Dan-Dan Du
Zong-Xue Zheng
Peng-Fei Shang
Xiao-Xia Yang
Chao Sun
Xiao-Yan Wang
Ya-Jie Tang
Xiu-Li Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.979474

2,434 views
8 citations

Review

Published on 25 Oct 2022

Acquired lymphedema: Molecular contributors and future directions for developing intervention strategies

in Translational Pharmacology

Ika Nurlaila
Kangsan Roh
Chang-Hwan Yeom
Hee Kang
Sukchan Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2022.873650

5,440 views
10 citations

Review

Published on 18 Oct 2022

Platelets and platelet extracellular vesicles in drug delivery therapy: A review of the current status and future prospects

in Translational Pharmacology

Zhanqiu Dai
Tingxiao Zhao
Nan Song
Kaifeng Pan
Yang Yang
Xunbin Zhu
Pengfei Chen
Jun Zhang
Chen Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1026386

9,995 views
36 citations

Original Research

Published on 17 Oct 2022

Machine learning advances the integration of covariates in population pharmacokinetic models: Valproic acid as an example

in Translational Pharmacology

Xiuqing Zhu
Ming Zhang
Yuguan Wen
Dewei Shang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.994665

4,848 views
14 citations

Original Research

Published on 17 Oct 2022

An individualized medication model of sodium valproate for patients with bipolar disorder based on machine learning and deep learning techniques

in Translational Pharmacology

Ping Zheng
Ze Yu
Liqian Mo
Yuqing Zhang
Chunming Lyu
Yongsheng Yu
Jinyuan Zhang
Xin Hao
Hai Wei
Fei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2022.890221

4,786 views
10 citations

Clinical Trial

Published on 13 Oct 2022

Efficacy and safety of remimazolam besylate in bronchoscopy for adults: A multicenter, randomized, double-blind, positive-controlled clinical study

in Translational Pharmacology

Ying-Yong Zhou
Shu-Ting Yang
Kai-Ming Duan
Zhi-Hong Bai
Yun-Fei Feng
Qu-Lian Guo
Zhi-Gang Cheng
Hui Wu
Wang-Ning Shangguan
Xiao-Min Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1005367

6,241 views
20 citations

Opinion

Published on 13 Oct 2022

Application of SMILES-based molecular generative model in new drug design

in Translational Pharmacology

Weiya Kong
Yuejuan Hu
Jiao Zhang
Qiaoyin Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1046524

7,303 views
7 citations

Original Research

Published on 10 Oct 2022

Stem cell‐derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy—In a model of human-induced pluripotent stem cell-derived cardiomyocytes

in Translational Pharmacology

Alina Constantin
Ioana Karla Comarița
Nicoleta Alexandru
Alexandru Filippi
Florina Bojin
Mihaela Gherghiceanu
Alexandra Vîlcu
Miruna Nemecz
Loredan Stefan Niculescu
Virgil Păunescu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1003684

8,126 views
19 citations

Clinical Trial

Published on 10 Oct 2022

The effects of dexmedetomidine for patient-controlled analgesia on postoperative sleep quality and gastrointestinal motility function after surgery: A prospective, randomized, double-blind, and controlled trial

in Translational Pharmacology

Xin Sui
Yue Wang
Mingxin Jin
Kun Li
Ge Jiang
Ailing Song
Zhaoyi He
Chengke Yin
Jingshun Zhao
Liping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.990358

3,759 views
9 citations

Review

Published on 10 Oct 2022

Effects of tocotrienol on aging skin: A systematic review

in Translational Pharmacology

Nur Izyani Ghazali
Rahimah Zahidah Mohd Rais
Suzana Makpol
Kok Yong Chin
Wei Ney Yap
Jo Aan Goon

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1006198

17,450 views
14 citations

Review

Published on 07 Oct 2022

The role of melatonin in the development of postmenopausal osteoporosis

in Translational Pharmacology

Keda Yang
Xueshan Qiu
Lili Cao
Shui Qiu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.975181

11,008 views
20 citations

Original Research

Published on 06 Oct 2022

Early ascorbic acid administration prevents vascular endothelial cell damage in septic mice

in Translational Pharmacology

Yutaro Madokoro
Chinatsu Kamikokuryo
Shuhei Niiyama
Takashi Ito
Satoshi Hara
Hiroshi Ichinose
Yasuyuki Kakihana

Frontiers in Pharmacology

doi 10.3389/fphar.2022.929448

6,058 views
10 citations

Original Research

Published on 04 Oct 2022

Design and evaluation of rufinamide nanocrystals loaded thermoresponsive nasal in situ gelling system for improved drug distribution to brain

in Translational Pharmacology

Avantika Dalvi
Punna Rao Ravi
Chandra Teja Uppuluri

Frontiers in Pharmacology

doi 10.3389/fphar.2022.943772

2,869 views
15 citations

Review

Published on 29 Sep 2022

Review on Plant-Based Management in Combating Antimicrobial Resistance - Mechanistic Perspective

in Translational Pharmacology

Masita Arip
Malarvili Selvaraja
Mogana R
Lee Fang Tan
Mun Yee Leong
Puay Luan Tan
Vi Lien Yap
Sasikala Chinnapan
Ng Chin Tat
Maha Abdullah

Frontiers in Pharmacology

doi 10.3389/fphar.2022.879495

11,612 views
33 citations