Frontiers in Pharmacology | Translational Pharmacology

Clinical Trial

Published on 11 Dec 2023

A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects

in Translational Pharmacology

Qian Chen
Qingqing Wu
Rong Song
Yating Wang
Mengqi Zhang
Fangqiong Li
Weifang Zeng
Wei Wang
Jingying Jia
Chen Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1296672

2,516 views
4 citations

Editorial

Published on 11 Dec 2023

Editorial: Disease-on-a-chip: from point-of-care to personalized medicine

in Translational Pharmacology

Andrea Cruz
Elisabete Fernandes
Raquel O. Rodrigues
Susana O. Catarino
Diana Pinho

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1344379

1,294 views

Original Research

Published on 07 Dec 2023

A synthetic notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay

in Translational Pharmacology

YangHao Fu
TianDuo Wang
John A. Ronald

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304194

5,849 views
3 citations

Original Research

Published on 06 Dec 2023

Quantitative systems pharmacology model of erythropoiesis to simulate therapies targeting anemia due to chronic kidney disease

in Translational Pharmacology

Mrittika Roy
Shaifali Saroha
Uddipan Sarma
Harini Sarathy
Rukmini Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1274490

2,871 views

Original Research

Published on 30 Nov 2023

Harnessing the translational power of bleomycin model: new insights to guide drug discovery for idiopathic pulmonary fibrosis

in Translational Pharmacology

Annalisa Murgo
Fabio Bignami
Giuseppina Federico
Gino Villetti
Maurizio Civelli
Angelo Sala
Daniela Miglietta

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1303646

3,924 views
2 citations

Review

Published on 27 Nov 2023

Verapamil chronicles: advances from cardiovascular to pancreatic β-cell protection

in Translational Pharmacology

Hossein Arefanian
Lubaina Koti
Sardar Sindhu
Rasheed Ahmad
Ashraf Al Madhoun
Fahd Al-Mulla

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1322148

3,686 views
5 citations

Original Research

Published on 24 Nov 2023

Population pharmacokinetics of everolimus in patients with seizures associated with focal cortical dysplasia

in Translational Pharmacology

Jinha Park
Se Hee Kim
Jongsung Hahn
Hoon-Chul Kang
Sang-Guk Lee
Heung Dong Kim
Min Jung Chang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1197549

2,412 views
2 citations

Clinical Trial

Published on 21 Nov 2023

Effect of Berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi-centric, open-label clinical trial

in Translational Pharmacology

Francesco Di Pierro
Ruqqia Sultana
Amna Zia Eusaph
Saida Abrar
Mahroo Bugti
Fauzia Afridi
Umer Farooq
Somia Iqtadar
Fareeha Ghauri
Syeda Makhduma

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1269605

26,313 views
7 citations

Original Research

Published on 14 Nov 2023

Intraoperative parameters and postoperative follow-up of foam-based intraperitoneal chemotherapy (FBIC)

in Translational Pharmacology

Carolina Khosrawipour
Jakub Nicpoń
Zdzisław Kiełbowicz
Przemysław Prządka
Bartłomiej Liszka
Said Al-Jundi
Veria Khosrawipour
Shiri Li
Hien Lau
Joanna Kulas

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1276759

1,676 views
1 citation

Case Report

Published on 10 Nov 2023

Case report: Supratherapeutic tacrolimus concentrations with nirmatrelvir/ritonavir in a lung transplant patient: a case report using Rifampin for reversal

in Translational Pharmacology

Yu Xiong
Xiaoxing Wang
Shu Li
Qian Zhang
Lijuan Guo
Wenhui Chen
Zhixia Zhao
Lihong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1285078

2,507 views
4 citations

Original Research

Published on 02 Nov 2023

Design of a multi-target focused library for antidiabetic targets using a comprehensive set of chemical transformation rules

in Translational Pharmacology

Fernanda I. Saldívar-González
Gabriel Navarrete-Vázquez
José L. Medina-Franco

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1276444

4,238 views
5 citations

Original Research

Published on 25 Oct 2023

Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model

in Translational Pharmacology

Victor Sokolov
Tatiana Yakovleva
Robert C. Penland
David W. Boulton
Weifeng Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1229255

1,828 views

Review

Published on 19 Oct 2023

Overcoming barriers: a review on innovations in drug delivery to the middle and inner ear

in Translational Pharmacology

Derek S. Delaney
Lawrence J. Liew
Joey Lye
Marcus D. Atlas
Elaine Y. M. Wong

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1207141

6,253 views
16 citations

Clinical Trial

Published on 09 Oct 2023

Safety and effectiveness of HSK21542 for hemodialysis patients: a multiple ascending dose study

in Translational Pharmacology

Mingming Pan
Guihua Wang
Li Zhou
Yan Xu
Li Yao
Chaoqing Wu
Changlin Mei
Zhanzheng Zhao
Dong Sun
Tianjun Guan

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1203642

3,729 views
7 citations

Original Research

Published on 04 Oct 2023

TRPA1-dependent and -independent activation by commonly used preservatives

in Translational Pharmacology

Maximilian L. Mager
Cosmin I. Ciotu
Markus Gold-Binder
Stefan Heber
Michael J. M. Fischer

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1248558

3,137 views
2 citations

Editorial

Published on 04 Oct 2023

Editorial: Innovative pharmacometric approaches to inform drug development and clinical use

in Translational Pharmacology

Maria Garcia-Cremades
Zinnia P. Parra-Guillen
Victor Mangas-Sanjuan
Hugo Geerts

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1274139

1,832 views