STUDY PROTOCOL article
Front. Psychiatry
Sec. Public Mental Health
Volume 16 - 2025 | doi: 10.3389/fpsyt.2025.1548638
This article is part of the Research TopicInnovating Public Mental Health: Integrating Digital Therapeutics for Comprehensive Mood Disorder ManagementView all articles
A 12-week cluster randomized controlled trial of the effectiveness of an AI-aided DICE algorithm for BPSD management in low-resource settings: A study protocol
Provisionally accepted
- 1Peking University Sixth Hospital, Beijing, China
- 2Beijing Haidian psychological rehabilitation hospital, Beijing, China
- 3Qingdao University, Qingdao, Shandong Province, China
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The "Describe-Investigate-Create-Evaluate" (DICE) approach has been considered a guide for managing behavioral and psychological symptoms of dementia (BPSD). However, limited resources may limit the implementation of the DICE approach. With the development of AI technology, the effectiveness of the AI-aided DICE algorithm for BPSD management has yet to be determined. Therefore, this study aims to examine the effectiveness of the AI-aided DICE algorithm for managing BPSD in low-resource settings.The cluster randomized controlled trial will be conducted in 12 medical facilities where geriatric psychiatrists are not fully installed. One hundred eighty-four persons with mild and moderate BPSD will be enrolled and randomized to the AI-aided DICE group (n=92) and usual care group (n=92). In the AI-aided DICE group, all participants will receive a comprehensive assessment on a digital triage platform to identify individualized needs and target symptoms, be prescribed a personalized management plan based on the AI-aided decision process, be monitor the implementation of the management plan, and receive follow-up assessment to evaluate the effectiveness. The neuropsychiatric inventory questionnaire and caregiver burden inventory will measure primary and secondary outcomes. The study duration for each participant will be 12 weeks.Discussion: The study will examine the effectiveness of the AI-aided DICE algorithm for managing BPSD in low-resource settings. The findings will support the implementation of an AI-aided algorithm and leverage the practice of quality care for dementia.
Keywords: Neuropsychiatric syndromes, Dice algorithm, AI-aided decision process, alzhaimer disease, Dementia
Received: 20 Dec 2024; Accepted: 28 Apr 2025.
Copyright: © 2025 Zheng, Zhang, Li, Ji and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Huali Wang, Peking University Sixth Hospital, Beijing, China
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