ORIGINAL RESEARCH article

Front. Psychiatry

Sec. Addictive Disorders

Volume 16 - 2025 | doi: 10.3389/fpsyt.2025.1584143

The role of personality functioning and childhood trauma in patients in opioid substitution treatment

Provisionally accepted
Laura  WaschulinLaura Waschulin1,2Stefan  HofnerStefan Hofner2Daniela  Bildstein-EbnerDaniela Bildstein-Ebner2Jürgen  FuchshuberJürgen Fuchshuber1,3Susanne  Hörz-SagstetterSusanne Hörz-Sagstetter4Klemens  MichlmayrKlemens Michlmayr2Ludwig  OhseLudwig Ohse4,5,6Karel  Dobroslav RiegelKarel Dobroslav Riegel7Victor  BlümlVictor Blüml1*
  • 1Medical University of Vienna, Vienna, Austria
  • 2Suchthilfe Wien gGmbH, Vienna, Austria
  • 3Grüner Kreis Society, Vienna, Austria, Vienna, Austria
  • 4Psychologische Hochschule Berlin, Berlin, Berlin, Germany
  • 5Health and Medical University Potsdam, Potsdam, Brandenburg, Germany
  • 6Ernst von Bergmann Clinic, Potsdam, Brandenburg, Germany
  • 7Charles University, Prague, Prague, Czechia

The final, formatted version of the article will be published soon.

Background: Personality pathology and childhood trauma are known to be associated with substance use disorders (SUDs) in general and opioid use disorders (OUDs) in particular but the complex relationship is only partially understood. Investigating personality functioning in patients with OUD is crucial for gaining a deeper understanding of the emergence and course of illness as well as for planning appropriate treatment strategies.Aims: To empirically investigate personality functioning in a sample of patients in opioid substitution treatment and to examine the associations between personality functioning, injecting drug use (IDU) and childhood trauma.Methods: In a cross-sectional design, 31 patients with OUDs currently in an opioid substitution treatment program were assessed with the revised Structured Interview for Personality Organization, the Structured Clinical Interview for DSM-5, the Addiction Severity Index -Lite and the Childhood Trauma Questionnaire. The sample consisted of 80.6% male and 19.4% female patients.The large majority (93.5%) of participants were diagnosed with severe impairment of personality functioning. Impaired personality functioning and higher rates of reported childhood trauma were associated with a younger age of onset of IDU and a greater number of years of IDU. Level of personality functioning showed a stronger statistical association with both IDU and the number of diagnosed personality disorders than reported childhood trauma.Conclusions: OUDs are associated with severely impaired personality functioning. Assessment of personality functioning can provide important information for treatment strategies in addition to categorical psychiatric diagnoses and trauma history.

Keywords: Personality functioning, substance use disorders, Opioid use disorders, Injecting drug use, childhood trauma

Received: 26 Feb 2025; Accepted: 27 May 2025.

Copyright: © 2025 Waschulin, Hofner, Bildstein-Ebner, Fuchshuber, Hörz-Sagstetter, Michlmayr, Ohse, Riegel and Blüml. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Victor Blüml, Medical University of Vienna, Vienna, Austria

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