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ORIGINAL RESEARCH article

Front. Psychiatry

Sec. Anxiety and Stress Disorders

Influencing Factors of Pregnancy-Related Anxiety in Advanced Maternal Age Primigravidas and the Development and Evaluation of Personalized Psychological Nursing Interventions

Provisionally accepted
Yan  GaoYan Gao1,2Lei  YangLei Yang1Jingwen  SunJingwen Sun2Yiping  NanYiping Nan3Li  HouLi Hou2Xiaomei  LiXiaomei Li1*
  • 1School of Nursing, Health Science Centre, Xi’an Jiaotong University, Xi’an, China
  • 2The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China
  • 3Nursing and Rehabilitation College, Xi’an Medical University, Xi’an, China

The final, formatted version of the article will be published soon.

Background: Primigravidas of advanced maternal age (AMA) encounter distinct challenges throughout pregnancy and are particularly susceptible to heightened levels of anxiety. Objective: To identify the influencing factors of pregnancy-related anxiety in AMA primigravidas and to develop, implement, and evaluate a personalized psychological nursing intervention. Methods: Phase I involved a cross-sectional survey of 300 AMA primigravidas to identify anxiety-influencing factors. Phase II was a randomized controlled trial (RCT) with 160 AMA primigravidas assigned to either a personalized psychological nursing intervention group or a standard care control group. Results: Phase I identified key factors influencing anxiety, including perceived pregnancy risks, social support, and self-efficacy. In Phase II, the intervention group showed significantly lower anxiety levels (p < 0.001), improved self-efficacy (p < 0.001), and higher satisfaction with prenatal care (p < 0.01) compared to the control group. Conclusion: Personalized psychological nursing interventions based on identified influencing factors effectively reduce anxiety and improve psychological well-being in AMA primigravidas. Implementation of such interventions in prenatal care could significantly enhance outcomes for this vulnerable population.

Keywords: Advanced maternal age, Primigravidas, Pregnancy-related anxiety, Psychological nursing, Personalized intervention

Received: 25 Jun 2025; Accepted: 29 Oct 2025.

Copyright: © 2025 Gao, Yang, Sun, Nan, Hou and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xiaomei Li, xiaomeili4201@163.com

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