ORIGINAL RESEARCH article
Front. Psychiatry
Sec. Anxiety and Stress Disorders
Influencing Factors of Pregnancy-Related Anxiety in Advanced Maternal Age Primigravidas and the Development and Evaluation of Personalized Psychological Nursing Interventions
Provisionally accepted- 1School of Nursing, Health Science Centre, Xi’an Jiaotong University, Xi’an, China
- 2The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China
- 3Nursing and Rehabilitation College, Xi’an Medical University, Xi’an, China
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Background: Primigravidas of advanced maternal age (AMA) encounter distinct challenges throughout pregnancy and are particularly susceptible to heightened levels of anxiety. Objective: To identify the influencing factors of pregnancy-related anxiety in AMA primigravidas and to develop, implement, and evaluate a personalized psychological nursing intervention. Methods: Phase I involved a cross-sectional survey of 300 AMA primigravidas to identify anxiety-influencing factors. Phase II was a randomized controlled trial (RCT) with 160 AMA primigravidas assigned to either a personalized psychological nursing intervention group or a standard care control group. Results: Phase I identified key factors influencing anxiety, including perceived pregnancy risks, social support, and self-efficacy. In Phase II, the intervention group showed significantly lower anxiety levels (p < 0.001), improved self-efficacy (p < 0.001), and higher satisfaction with prenatal care (p < 0.01) compared to the control group. Conclusion: Personalized psychological nursing interventions based on identified influencing factors effectively reduce anxiety and improve psychological well-being in AMA primigravidas. Implementation of such interventions in prenatal care could significantly enhance outcomes for this vulnerable population.
Keywords: Advanced maternal age, Primigravidas, Pregnancy-related anxiety, Psychological nursing, Personalized intervention
Received: 25 Jun 2025; Accepted: 29 Oct 2025.
Copyright: © 2025 Gao, Yang, Sun, Nan, Hou and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaomei Li, xiaomeili4201@163.com
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