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ORIGINAL RESEARCH article

Front. Psychiatry

Sec. Anxiety and Stress Disorders

This article is part of the Research TopicStress-induced Psychopathology: From Mechanisms to InterventionsView all 13 articles

A study on long-term trauma-related mental health outcomes among Kurdish survivors of chemical attacks

Provisionally accepted
Ibrahim  MohammedIbrahim Mohammed1*Hataw  Ahmed SharifHataw Ahmed Sharif2Bushra  HasinBushra Hasin3Jan  KizilhanJan Kizilhan4Hemn  NarimanHemn Nariman5Salah  AhmedSalah Ahmed6Azad  QaderAzad Qader3Segi  PapiolSegi Papiol7Monika  RubekeilMonika Rubekeil7Thomas  G SchulzeThomas G Schulze10,7,8,9Urs  HeilbronnerUrs Heilbronner7Martin  HAUTZINGERMartin HAUTZINGER2
  • 1University of Tübingen, Tübingen, Germany
  • 2Eberhard Karls Universitat Tubingen, Tübingen, Germany
  • 3University of Sulaimani, Sulaymaniyah, Iraq
  • 4Duale Hochschule Baden Wurttemberg, Stuttgart, Germany
  • 5Qaiwan International University, Sulaymaniyah, Iraq
  • 6Jiyan Foundation for Human Rights, Erbil, Iraq
  • 7LMU Klinikum Institut fur Psychiatrische Phanomik und Genomik, Munich, Germany
  • 8SUNY Upstate Medical University Hospital, Syracuse, United States
  • 9Johns Hopkins Medicine Department of Psychiatry and Behavioral Sciences, Baltimore, United States
  • 10SUNY Downstate Health Sciences University Department of Psychiatry & Behavioral Sciences, New York, United States

The final, formatted version of the article will be published soon.

Background: The Kurdistan region experienced a series of devastating events, such as the 1988 chemical attacks and the 2014 Yazidi genocide, which have had substantial impacts on the This is a provisional file, not the final typeset article psychological and physical health of survivors. Objectives: This study evaluates the long-term mental health of individuals who were exposed to chemical gas, with a focus on the prevalence and severity of psychological symptoms and their associations with sociodemographic, clinical, and trauma-related factors. Methods: A total of 534 participants were recruited (300 females and 234 males). Data collection was completed in seven months, from March to September 2023. All participants completed validated psychological assessments, including the PTSD Checklist for DSM-5 (PCL-5), Patient Health Questionnaire-15 (PHQ-15), and Hopkins Symptom Checklist-25 (HSCL-25). Multivariate General Linear Modeling (GLM) was performed, adjusting for trauma exposure to simultaneously assess the effects of demographic and clinical variables on multiple symptom domains. Results: Most of the participants exhibited clinically significant symptoms, with 78.8% meeting the post-traumatic stress disorder (PTSD) threshold and 46.3% exhibiting comorbid symptoms across multiple domains. The GLM demonstrated that gender, trauma exposure, education level, and clinical factors were significantly associated with symptom severity across PTSD, somatic, and anxiety/depression symptoms (p .001). The model explained up to 47% of variance in symptom outcomes. After adjusting for covariates, women showed higher symptom severity than men. Greater trauma exposure and lower education independently predicted increased symptoms. Conclusion: These findings highlight serious psychological and somatic effects among survivors and underscore the urgent need for targeted mental health interventions for those affected by chemical attacks, with particular attention to individuals with lower levels of education and socioeconomic status, while incorporating gender-sensitive approaches to address differential vulnerabilities.

Keywords: PTSD1, depression2, Mental Health3, Chemical Attacks4, war5

Received: 26 Aug 2025; Accepted: 24 Nov 2025.

Copyright: © 2025 Mohammed, Sharif, Hasin, Kizilhan, Nariman, Ahmed, Qader, Papiol, Rubekeil, Schulze, Heilbronner and HAUTZINGER. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Ibrahim Mohammed, hama-seed-ibrahim.mohammed@uni-tuebingen.de

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