Emerging diseases have significantly impacted the last few decades (1–10). The emergence and re-emergence of vector-borne and zoonotic diseases in Africa, Asia, and Latin America have reshaped the epidemiological landscape of these continents. The impact of these diseases and the establishment of local transmission in traditionally non-endemic areas, due to migration and travel, have been revealed over the last years. Diseases such as Chikungunya (11–16), Zika (17–24), Yellow Fever (25–28), Dengue (29–33), Oropouche, Madre de Dios virus, Iquitos virus (34, 35), Mayaro Fever (36, 37), Ebola (38–42), Nipah virus, arenaviruses such as Lassa (43), Machupo (44, 45), Chapare (45, 46), Junin (47), zoonotic Malaria (48), Severe Fever with Thrombocytopenia Syndrome (49), Plague (50), Crimean-Congo Hemorrhagic Fever, Acute Orally Transmitted Chagas Disease (51–54), Visceral and Diffuse Cutaneous Leishmaniasis (55, 56), Toxoplasmosis (57–59), Tick-Borne Diseases (60, 61), Rift Valley Fever, Tuberculosis (62), Leprosy (63–67), Avian Influenza (68–70), Orthohantavirus (71–75), and Toxocariasis (76, 77) have posed a significant impact to human health. Furthermore, zoonotic epidemics and pandemic coronaviruses, such as the Severe Acute Respiratory Syndrome (SARS), the Middle East Respiratory Syndrome (MERS) (78–82), and the ongoing SARS-CoV-2/COVID-19 (83, 84) pandemic, have caused a profound economical and social disruption threatening to overwhelm public health systems globally (85) (Table 1). Most of these pathogens can even cocirculate and coinfect a significant proportion of inhabitants within the same territories (11, 87–94). For example, in arboviral diseases, the occurrence of coinfections has been widely reported –such as Dengue with Chikungunya and/or with Zika virus– and affects diverse populations, including pregnant women and immunocompromised patients (94–97). This may obscure clinical suspicion, as signs and symptoms for many of these pathogens may overlap. In endemic areas, this becomes a particularly pressing issue that must be taken into account in order to ensure accurate diagnosis and provide appropriate management. The ChikDenMaZika syndrome has been previously adopted as a mnemonic device to include Chikungunya, Dengue, Mayaro, and Zika in the broad differential of acute febrile illnesses due to arboviral agents (95). More recently, emerging coinfections, including bacterial and parasitic diseases, such as tuberculosis and Chagas disease, have also been reported (98).
Table 1
| • Avoid fragmentation and segmentation of the health system |
| • Enhance data integration between sectors |
| • Improve transfer of inputs and deployment of personnel |
| • Better linking of health and safety authorities |
| • Build up a strong capacity for molecular (RT‐PCR) testing |
| • Validate rapid tests for complementary diagnosis |
| • Improve primary care interventions before admission to ICU |
| • Improve ICU capacities including facilities, equipment, and personnel |
| • Better management and monitoring of non‐COVID patients |
| • Promote education of human resources, including health professionals |
| • Improve health personnel’s working conditions (salaries, PPE, among others) |
| • Enhance medical training during the pandemic |
| • Warrant medicinal oxygen supplement |
| • Monitor transparency in health authorities’ decision‐making documents |
| • Use of medications with evidence and develop evidence-based guidelines |
| • Provide appropiate information about public health policy and decision‐making processes |
| • Develop more capacities in biotechnology (for development of tests, treatments, and vaccines) |
Lessons learned from the COVID-19 pandemic in Latin America.
Modified from Herrera-Añazco et al. (86).
Current times call for more comprehensive ecoepidemiological and bioecosocial approaches (20, 99). Scarce funding and the lack of research (39, 43, 61, 81) in tropical medicine are entirely unacceptable. Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), tuberculosis (TB), and malaria combined receive approximately 70% of neglected diseases funding. As mentioned here, emerging tropical diseases, such as those mentioned here, are worldwide in scope, and many have significant regional implications. Therefore, a different funding paradigm that improves their situation is needed (100). The world is no longer a place with distant countries and shielded territories. Instead, ever increasing interconnectivity has turned it into a “small” global village, where the health status of underprivileged areas may undermine not only their lives and development but extend to the wealthiest. The Ebola crisis in 2014 highlighted how high-consequence emerging diseases could spill over to Europe and North America (38, 40). The ongoing 2020-2021 pandemic of COVID-19, which has reached as far as Antarctica, affecting almost all countries worldwide, is another clear example (8, 29, 84, 101–112). As was expected, coinfections between tropical pathogens and COVID-19 are also now increasingly being reported, especially with dengue (30). Dengue affects over 100 countries worldwide and puts about 2.5-3.9 billion people at risk of infection (113, 114). Within the next century, nearly a billion people are at risk of exposure to virus transmission by both main Aedes spp., Ae. aegypti, and Ae. albopictus (also Chikungunya and Zika) in the worst-case scenario (115). The recent first detection of Ae. vittatus in the Dominican Republic and the Americas generated concern in the region, requiring enhanced surveillance to understand the range and public health risks of this potential invasive mosquito species, deserving more studies (116). Most of these emerging tropical diseases are vector-borne, zoonotically transmitted, or environmentally spread through direct contact, food or water ingestion, as well as a consequence of environmental alterations (including the effects of climate change) (117–125), becoming significant sources of mortality and morbidity worldwide (2).
The impact of these diseases extends well beyond the acute constellation of symptoms, leading in a considerable proportion of patients to chronic sequelae and complications, which can be long lasting and severely incapacitating, as is the case with Chikungunya (15, 126–132), Zika (17, 133–135), Ebola, Chagas disease (52), and even for COVID-19 (136–139).
Many tools have been deployed to counteract emerging infectious diseases. Amongst these are active surveillance (some supported by artificial intelligence) (140–142), leading to the rapid identification of novel pathogens by genome sequencing and phylogenetic tracing studies (36, 105, 107, 143–146) based on computing methods to predict possible interspecies barriers spillover between humans and animals (147). Coupling biotechnological approaches with social sciences—the holistic understanding of humans and their interactions in the disease ecosystems—is also a critical element needed when studying emerging infectious diseases (148, 149).
One of the most significant challenges when studying tropical infectious diseases relies on their complexity and heterogeneity, which usually requires a deep understanding not only of the disease itself but its overall context. In order to better approach these diseases one must keep a broader vision of designing proposed interventions, including multilevel ecoepidemiological studies ranging from molecular and omics to satellite epidemiology (use of data and images derived from geospatial technologies, e.g., satellites, for the study of the occurrence and distribution of health-related events in specified populations, and the application of this knowledge to control the health problems) of pathogens, vectors, hosts, abiotic variables, and other socio-environmental factors (125, 150, 151). While more research is required to fill in the numerous gaps in knowledge for many of these diseases, particular attention should be placed in designing strategies to develop methods to forecast these diseases not only in vulnerable and underserved populations from low-income countries but also in those poverty pockets located in high-income countries. A whole chapter to be considered in emerging tropical diseases is vaccines development. Innovative global partnership between public, private, philanthropic, and civil society organisations, such as the Coalition for Epidemic Preparedness Innovations (CEPI), launched in 2017, are important to develop vaccines to stop future epidemics. To accelerate the development of vaccines against emerging infectious diseases and enable equitable access to these vaccines for people during outbreaks is crucial. Nevertheless, more funding to understand biology, pathogenesis, epidemiology, prevention, and treatment of emerging tropical diseases are urgently needed and expected (152–154).
Tropical Medicine is no more a clinical specialty of “exotic diseases,” as it was conceived at its beginnings, and is no more about “diseases for those entering the jungle.” One dramatic change is the urban installation of diseases that before were observed only after sylvatic or primary forest exposure. The increase of urban outbreaks of Chagas disease in South America is now a horrific reality in Brazil (155–157), Venezuela (158), and Colombia (159, 160), and it is also a new reality for visceral leishmaniasis (161–164). The integrated work of public health experts, veterinarians, entomologists, and parasitologists is an urgent need to face these new challenges and transformations of tropical diseases. Tropical diseases also include non-infectious diseases, such as animal bites and stings (e.g. myiasis and tungiasis) (165, 166). Snake bites, scorpion stings, and spider bites, account for a significant amount of the morbidity and mortality in tropical countries in these changing scenarios, including ecotourism, rural migration, and other related factors (167–170).
There is no doubt that “many things are wrong in the world today”, as the legendary American rock n’roll band Aerosmith has been singing since the 90s. We are “living on the edge”, the edge of neglect and of a surge of many emerging infectious diseases with no hope for resolution in the foreseeable future. Furthermore, “it sure ain’t no surprise” that poverty, inequality, climate change, deforestation, migration, urbanization, wildlife trade, among many other factors, have all contributed to the emergence of novel tropical diseases and the resurgence of other endemic diseases (171). There is no spare place for the arrival of emerging pathogens, and over time pathogens tend to adapt to new environments leading to unforeseen consequences. The next epidemic, the next pandemic, is just around the corner (68). In response to this latent threat, we need to gather real-time information and build collaborative networks aimed to enhance surveillance activities in order to develop high-priority medical countermeasures to prevent and control emerging tropical diseases. Research in Zoonotic and Vector-Borne Emerging Tropical Diseases remains the most critical aspect and the foundation to determine the drivers of emerging and re-emerging infectious diseases.
With that vision, our new Section Emerging Tropical Diseases in the journal Frontiers in Tropical Diseases offers to contribute to the scientific advancement and fill in the many knowledge gaps based on a multi and transdisciplinary approach. Our team of Associate Editors is comprised of a diverse group of experts from different countries, diverse backgrounds, and varied interrelated expertises in a wide range of conditions within the tropical diseases spectrum of diseases, following the One Health approach vision (8, 172).
Grand challenges exist in the fight against the threat of emerging tropical diseases. In the laboratory, our daily work, in the hospitals, in the field, in the community, and in many other places, our shared goal is to understand the drivers of emergence and address their root-causes. We are working collaboratively in social networks to reduce the impact of emerging tropical diseases. Let’s work on this together! We value your work and welcome your submissions to this new section of Frontiers in Tropical Diseases.
Statements
Author contributions
All authors contributed to manuscript conception and design, literature review, manuscript preparation, and critical review. All authors contributed to the article and approved the submitted version.
Acknowledgments
AR-M is the Specialty Chief Editor in Emerging Tropical Diseases of Frontiers in Tropical Diseases. The remaining authors of this article are their Associate Editors. This is a collaborative article of the Network NHEPACHA.
Conflict of interest
RB-M was employed by Laboratorios Lokímica, Spain.
The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
References
1
Alfaro-TolozaPClouet-HuertaDERodriguez-MoralesAJ. Chikungunya, the Emerging Migratory Rheumatism. Lancet Infect Dis (2015) 15(5):510–2. doi: 10.1016/S1473-3099(15)70160-X
2
McArthurDB. Emerging Infectious Diseases. Nurs Clin North Am (2019) 54(2):297–311. doi: 10.1016/j.cnur.2019.02.006
3
ShiZ. Emerging Infectious Diseases Associated With Bat Viruses. Sci China Life Sci (2013) 56(8):678–82. doi: 10.1007/s11427-013-4517-x
4
LiuSLSaifL. Emerging Viruses Without Borders: The Wuhan Coronavirus. Viruses (2020) 12(2):130. doi: 10.3390/v12020130
5
GillCMBeckhamJDPiquetALTylerKLPastulaDM. Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu. Semin Neurol (2019) 39(4):419–27. doi: 10.1055/s-0039-1687839
6
Millan-OñateJRodríguez-MoralesAJCamacho-MorenoGMendoza-RamírezHRodríguez-SabogalIAÁlvarez-MorenoC. A New Emerging Zoonotic Virus of Concern: The 2019 Novel Coronavirus (Covid-19). Infectio (2020) 24(3):187–92. doi: 10.22354/in.v24i3.848
7
CarrionMMadoffLC. ProMED-mail: 22 Years of Digital Surveillance of Emerging Infectious Diseases. Int Health (2017) 9(3):177–83. doi: 10.1093/inthealth/ihx014
8
Bonilla-AldanaDKDhamaKRodriguez-MoralesAJ. Revisiting the One Health Approach in the Context of COVID-19: A Look Into the Ecology of This Emerging Disease. Adv Anim Vet Sci (2020) 8(3):234–7. doi: 10.17582/journal.aavs/2020/8.3.234.237
9
de WitEvan DoremalenNFalzaranoDMunsterVJ. SARS and MERS: Recent Insights Into Emerging Coronaviruses. Nat Rev Microbiol (2016) 14(8):523–34. doi: 10.1038/nrmicro.2016.81
10
Rodriguez-MoralesAJ. Zika and Microcephaly in Latin America: An Emerging Threat for Pregnant Travelers? Travel Med Infect Dis (2016) 14(1):5–6. doi: 10.1016/j.tmaid.2016.01.011
11
Rodriguez-MoralesAJVillamil-GomezWEFranco-ParedesC. The Arboviral Burden of Disease Caused by Co-Circulation and Co-Infection of Dengue, Chikungunya and Zika in the Americas. Travel Med Infect Dis (2016) 14(3):177–9. doi: 10.1016/j.tmaid.2016.05.004
12
Escalera-AntezanaJPMurillo-GarciaDRRodriguez-MoralesAJ. Chikungunya in Bolivia: Still a Neglected Disease? Arch Med Res (2018) 49(4):288. doi: 10.1016/j.arcmed.2018.09.002
13
ZambranoLISierraMLaraBRodriguez-NunezIMedinaMTLozada-RiascosCOet al. Estimating and Mapping the Incidence of Dengue and Chikungunya in Honduras During 2015 Using Geographic Information Systems (Gis). J Infect Public Health (2017) 10(4):446–56. doi: 10.1016/j.jiph.2016.08.003
14
Bonilla-AldanaDKBonilla-AldanaJLGarcia-BustosJJLozadaCORodriguez-MoralesAJ. Geographical Trends of Chikungunya and Zika in the Colombian Amazonian Gateway Department, Caqueta, 2015-2018 - Implications for Public Health and Travel Medicine. Travel Med Infect Dis (2020) 35:101481. doi: 10.1016/j.tmaid.2019.101481
15
Rodriguez-MoralesAJCardona-OspinaJAFernanda Urbano-GarzonSSebastian Hurtado-ZapataJ. Prevalence of Post-Chikungunya Infection Chronic Inflammatory Arthritis: A Systematic Review and Meta-Analysis. Arthritis Care Res (Hoboken) (2016) 68(12):1849–58. doi: 10.1002/acr.22900
16
Rodriguez-MoralesAJPaniz-MondolfiAE. Venezuela: Far From the Path to Dengue and Chikungunya Control. J Clin Virol (2015) 66:60–1. doi: 10.1016/j.jcv.2015.02.020
17
Villamil-GomezWEGuijarroECastellanosJRodriguez-MoralesAJ. Congenital Zika Syndrome With Prolonged Detection of Zika Virus RNA. J Clin Virol (2017) 95:52–4. doi: 10.1016/j.jcv.2017.08.010
18
Cardona-OspinaJAHenao-SanMartinVAcevedo-MendozaWFNasner-PossoKMMartinez-PulgarinDFRestrepo-LopezAet al. Fatal Zika Virus Infection in the Americas: A Systematic Review. Int J Infect Dis (2019) 88:49–59. doi: 10.1016/j.ijid.2019.08.033
19
ZambranoLIFuentes-BarahonaICSoto-FernandezRJZunigaCda SilvaJCRodriguez-MoralesAJ. Guillain-Barre Syndrome Associated With Zika Virus Infection in Honduras, 2016-2017. Int J Infect Dis (2019) 84:136–7. doi: 10.1016/j.ijid.2019.05.008
20
Rodriguez-MoralesAJRuizPTabaresJOssaCAYepes-EcheverryMCRamirez-JaramilloVet al. Mapping the Ecoepidemiology of Zika Virus Infection in Urban and Rural Areas of Pereira, Risaralda, Colombia, 2015-2016: Implications for Public Health and Travel Medicine. Travel Med Infect Dis (2017) 18:57–66. doi: 10.1016/j.tmaid.2017.05.004
21
Rodriguez-MoralesAJGalindo-MarquezMLGarcia-LoaizaCJSabogal-RomanJAMarin-LoaizaSAyalaAFet al. Mapping Zika Virus Disease Incidence in Valle Del Cauca. Infection (2017) 45(1):93–102. doi: 10.1007/s15010-016-0948-1
22
NishiuraHMizumotoKVillamil-GomezWERodriguez-MoralesAJ. Preliminary Estimation of the Basic Reproduction Number of Zika Virus Infection During Colombia Epidemic, 2015-2016. Travel Med Infect Dis (2016) 14(3):274–6. doi: 10.1016/j.tmaid.2016.03.016
23
ZambranoLIVasquez-BonillaWOFuentes-BarahonaICClaudio da SilvaJValle-ReconcoJAMedinaMTet al. Spatial Distribution of Zika in Honduras During 2016-2017 Using Geographic Information Systems (GIS) - Implications for Public Health and Travel Medicine. Travel Med Infect Dis (2019) 31:101382. doi: 10.1016/j.tmaid.2019.01.017
24
HamerDHBarbreKAChenLHGrobuschMPSchlagenhaufPGoorhuisAet al. Travel-Associated Zika Virus Disease Acquired in the Americas Through February 2016: A GeoSentinel Analysis. Ann Intern Med (2017) 166(2):99–108. doi: 10.7326/M16-1842
25
RifakisPMBenitezJADe-la-Paz-PinedaJRodriguez-MoralesAJ. Epizootics of Yellow Fever in Venezuela (2004-2005): An Emerging Zoonotic Disease. Ann N Y Acad Sci (2006) 1081:57–60. doi: 10.1196/annals.1373.005
26
RenoEQuanNGFranco-ParedesCChastainDBChauhanLRodriguez-MoralesAJet al. Prevention of Yellow Fever in Travellers: An Update. Lancet Infect Dis (2020) 20(6):e129–e37. doi: 10.1016/S1473-3099(20)30170-5
27
ChavesTOrdunaTLepeticAMacchiAVerbanazSRisquezAet al. Yellow Fever in Brazil: Epidemiological Aspects and Implications for Travelers. Travel Med Infect Dis (2018) 23:1–3. doi: 10.1016/j.tmaid.2018.05.001
28
Ortiz-MartinezYPatino-BarbosaAMRodriguez-MoralesAJ. Yellow Fever in the Americas: The Growing Concern About New Epidemics. F1000Res (2017) 6:398. doi: 10.12688/f1000research.11280.1
29
NavarroJCArrivillaga-HenriquezJSalazar-LoorJRodriguez-MoralesAJ. Covid-19 and Dengue, Co-Epidemics in Ecuador and Other Countries in Latin America: Pushing Strained Health Care Systems Over the Edge. Travel Med Infect Dis (2020) 37:101656. doi: 10.1016/j.tmaid.2020.101656
30
Cardona-OspinaJAArteaga-LiviasKVillamil-GomezWEPerez-DiazCEKatterine Bonilla-AldanaDMondragon-CardonaAet al. Dengue and COVID-19, Overlapping Epidemics? An Analysis From Colombia. J Med Virol (2021) 93(1):522–7. doi: 10.1002/jmv.26194
31
ZambranoLIRodriguezEEspinoza-SalvadoIARodriguez-MoralesAJ. Dengue in Honduras and the Americas: The Epidemics are Back! Travel Med Infect Dis (2019) 31:101456. doi: 10.1016/j.tmaid.2019.07.012
32
Quintero-HerreraLLRamirez-JaramilloVBernal-GutierrezSCardenas-GiraldoEVGuerrero-MatituyEAMolina-DelgadoAHet al. Potential Impact of Climatic Variability on the Epidemiology of Dengue in Risaralda, Colombia, 2010-2011. J Infect Public Health (2015) 8(3):291–7. doi: 10.1016/j.jiph.2014.11.005
33
ZambranoLIRodriguezEEspinoza-SalvadoIAFuentes-BarahonaICLyra de OliveiraTLuciano da VeigaGet al. Spatial Distribution of Dengue in Honduras During 2016-2019 Using a Geographic Information Systems (GIS)-Dengue Epidemic Implications for Public Health and Travel Medicine. Travel Med Infect Dis (2019) 32:101517. doi: 10.1016/j.tmaid.2019.101517
34
NavarroJCGiambalvoDHernandezRAugusteAJTeshRBWeaverSCet al. Isolation of Madre De Dios Virus (Orthobunyavirus; Bunyaviridae), an Oropouche Virus Species Reassortant, From a Monkey in Venezuela. Am J Trop Med Hyg (2016) 95(2):328–38. doi: 10.4269/ajtmh.15-0679
35
AguilarPVBarrettADSaeedMFWattsDMRussellKGuevaraCet al. Iquitos Virus: A Novel Reassortant Orthobunyavirus Associated With Human Illness in Peru. PloS Negl Trop Dis (2011) 5(9):e1315. doi: 10.1371/journal.pntd.0001315
36
AugusteAJLiriaJForresterNLGiambalvoDMoncadaMLongKCet al. Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated During an Outbreak, Venezuela, 2010. Emerg Infect Dis (2015) 21(10):1742–50. doi: 10.3201/eid2110.141660
37
Aguilar-LuisMADel Valle-MendozaJSandovalISilva-CasoWMazulisFCarrillo-NgHet al. A Silent Public Health Threat: Emergence of Mayaro Virus and Co-Infection With Dengue in Peru. BMC Res Notes (2021) 14(1):29. doi: 10.1186/s13104-021-05444-8
38
Rodriguez-MoralesAJMarin-RinconHASepulveda-AriasJCPaniz-MondolfiAE. Assessing the Potential Migration of People From Ebola Affected West African Countries to Latin America. Travel Med Infect Dis (2015) 13(3):264–6. doi: 10.1016/j.tmaid.2014.12.015
39
Cruz-CalderonSNasner-PossoKMAlfaro-TolozaPPaniz-MondolfiAERodriguez-MoralesAJ. A Bibliometric Analysis of Global Ebola Research. Travel Med Infect Dis (2015) 13(2):202–4. doi: 10.1016/j.tmaid.2015.02.007
40
Cardona-OspinaJAGiselle-BadilloACalvache-BenavidesCERodriguez-MoralesAJ. Ebola Virus Disease: An Emerging Zoonosis With Importance for Travel Medicine. Travel Med Infect Dis (2014) 12(6 Pt A):682–3. doi: 10.1016/j.tmaid.2014.10.014
41
Rodriguez-MoralesAJHenaoDEFrancoTBMayta-TristanPAlfaro-TolozaPPaniz-MondolfiAE. Ebola: A Latent Threat to Latin America. Are We Ready? Travel Med Infect Dis (2014) 12(6 Pt A):688–9. doi: 10.1016/j.tmaid.2014.11.002
42
Patino-BarbosaAMArroyave-ValenciaFGarcia-RamirezLMVallejo-AtehortuaEArciniegas-PantojaMRodriguez-MoralesAJet al. Healthcare Students’ and Workers’ Knowledge About Epidemiology and Symptoms of Ebola in One City of Colombia. J Hosp Infect (2015) 90(4):356–8. doi: 10.1016/j.jhin.2015.05.001
43
Almeida-GuerreroAOlaya-GomezJCSanchez-RamirezNMurillo-GarciaDRCardona-OspinaJALagos-GrisalesGJet al. Mitigation of the Global Impact of Lassa Fever: Have We Investigated Enough About This Arenavirus? - A Bibliometric Analysis of Lassa Fever Research. Travel Med Infect Dis (2018) 24:13–4. doi: 10.1016/j.tmaid.2018.06.012
44
Rodriguez-MoralesAJCastañeda-HernándezDMEscalera-AntezanaJPAlvarado-ArnezLE. Organisms of Concern But Not Foodborne or Confirmed Foodborne: Bolivian Hemorrhagic Fever Virus (Machupo Virus)☆. Reference Module Food Sci: Elsevier (2019). doi: 10.1016/B978-0-08-100596-5.22639-5
45
Silva-RamosCRFaccini-MartínezÁACalixtoO-JHidalgoM. Bolivian Hemorrhagic Fever: A Narrative Review. Travel Med Infect Dis (2021) 40:102001. doi: 10.1016/j.tmaid.2021.102001
46
Escalera-AntezanaJPRodriguez-VillenaOJArancibia-AlbaAWAlvarado-ArnezLEBonilla-AldanaDKRodriguez-MoralesAJ. Clinical Features of Fatal Cases of Chapare Virus Hemorrhagic Fever Originating From Rural La Paz, Bolivia, 2019: A Cluster Analysis. Travel Med Infect Dis (2020) 36:101589. doi: 10.1016/j.tmaid.2020.101589
47
VanellaJMGonzalezLEPagliniSMarquezA. [Laboratory Evidence of the Activity of Junin Virus in the Southeast of Cordoba: Hypothesis on Its Epidemiology]. Dia Med (1964) 36:290–1.
48
Rodriguez-MoralesAJ. Malaria: An Eradicable Threat? J Infect Dev Ctries (2008) 2(1):1–2. doi: 10.3855/jidc.316
49
Rodriguez-MoralesAJRamirez-JaramilloVPatino-BarbosaAMBedoya-AriasHAHenao-SanMartinVMurillo-GarciaDRet al. Severe Fever With Thrombocytopenia Syndrome - A Bibliometric Analysis of an Emerging Priority Disease. Travel Med Infect Dis (2018) 23:97–8. doi: 10.1016/j.tmaid.2018.04.010
50
Rodriguez-MoralesAJEscalera-AntezanaJPAlvarado-ArnezLE. Is Plague Globally Reemerging? Infectio (2019) 23:7–9. doi: 10.22354/in.v23i1.748
51
Franco-ParedesCVillamil-GomezWESchultzJHenao-MartinezAFParra-HenaoGRassiA Jret al. A Deadly Feast: Elucidating the Burden of Orally Acquired Acute Chagas Disease in Latin America - Public Health and Travel Medicine Importance. Travel Med Infect Dis (2020) 36:101565. doi: 10.1016/j.tmaid.2020.101565
52
ChadalawadaSSillauSArchuletaSMundoWBandaliMParra-HenaoGet al. Risk of Chronic Cardiomyopathy Among Patients With the Acute Phase or Indeterminate Form of Chagas Disease: A Systematic Review and Meta-Analysis. JAMA Netw Open (2020) 3(8):e2015072. doi: 10.1001/jamanetworkopen.2020.15072
53
MadiganRMajoySRitterKLuis ConcepcionJMarquezMESilvaSCet al. Investigation of a Combination of Amiodarone and Itraconazole for Treatment of American Trypanosomiasis (Chagas Disease) in Dogs. J Am Vet Med Assoc (2019) 255(3):317–29. doi: 10.2460/javma.255.3.317
54
Villamil-GomezWEEcheverriaLEAyalaMSMunozLMejiaLEyes-EscalanteMet al. Orally Transmitted Acute Chagas Disease in Domestic Travelers in Colombia. J Infect Public Health (2017) 10(2):244–6. doi: 10.1016/j.jiph.2016.05.002
55
Villamil-GomezWECalderon-GomezcaseresARodriguez-MoralesAJ. Visceral Leishmaniasis in a Patient With Systemic Lupus Erythematosus From Colombia, Latin America. Infez Med (2019) 27(1):106–8.
56
Arteaga-LiviasKSantos-HuertaMDamaso-MataBPanduro-CorreaVGonzales-ZamoraJARodriguez-MoralesAJ. Disseminated Cutaneous Leishmaniasis in a Pediatric Patient From Peru. J Trop Pediatr (2020). doi: 10.1093/tropej/fmaa051
57
Hernandez-de-Los-RiosAMurillo-LeonMMantilla-MurielLEArenasAFVargas-MontesMCardonaNet al. Influence of Two Major Toxoplasma Gondii Virulence Factors (ROP16 and ROP18) on the Immune Response of Peripheral Blood Mononuclear Cells to Human Toxoplasmosis Infection. Front Cell Infect Microbiol (2019) 9:413. doi: 10.3389/fcimb.2019.00413
58
PfaffAWde-la-TorreARochetEBrunetJSabouMSauerAet al. New Clinical and Experimental Insights Into Old World and Neotropical Ocular Toxoplasmosis. Int J Parasitol (2014) 44(2):99–107. doi: 10.1016/j.ijpara.2013.09.007
59
El BissatiKLevignePLykinsJAdlaouiEBBarkatABerrahoAet al. Global Initiative for Congenital Toxoplasmosis: An Observational and International Comparative Clinical Analysis. Emerg Microbes Infect (2018) 7(1):1–14. doi: 10.1038/s41426-018-0164-4
60
Rodriguez-MoralesAJBonilla-AldanaDKIdarraga-BedoyaSEGarcia-BustosJJCardona-OspinaJAFaccini-MartinezAA. Epidemiology of Zoonotic Tick-Borne Diseases in Latin America: Are We Just Seeing the Tip of the Iceberg? F1000Res (2018) 7:1988. doi: 10.12688/f1000research.17649.1
61
Rodriguez-MoralesAJBonilla-AldanaDKEscalera-AntezanaJPAlvarado-ArnezLE. Research on Babesia: A Bibliometric Assessment of a Neglected Tick-Borne Parasite. F1000Res (2018) 7:1987. doi: 10.12688/f1000research.17581.1
62
Cubillos-AnguloJMArriagaMBMeloMGMSilvaECAlvarado-ArnezLEde AlmeidaASet al. Polymorphisms in Interferon Pathway Genes and Risk of Mycobacterium Tuberculosis Infection in Contacts of Tuberculosis Cases in Brazil. Int J Infect Dis (2020) 92:21–8. doi: 10.1016/j.ijid.2019.12.013
63
Alvarado-ArnezLEAmaralEPSales-MarquesCDuraesSMCardosoCCNunes SarnoEet al. Association of IL10 Polymorphisms and Leprosy: A Meta-Analysis. PloS One (2015) 10(9):e0136282. doi: 10.1371/journal.pone.0136282
64
Franco-ParedesCMarcosLAHenao-MartinezAFRodriguez-MoralesAJVillamil-GomezWEGotuzzoEet al. Cutaneous Mycobacterial Infections. Clin Microbiol Rev (2018) 32(1):e00069–18. doi: 10.1128/CMR.00069-18
65
Sales-MarquesCCardosoCCAlvarado-ArnezLEIllaramendiXSalesAMHackerMAet al. Genetic Polymorphisms of the IL6 and NOD2 Genes are Risk Factors for Inflammatory Reactions in Leprosy. PloS Negl Trop Dis (2017) 11(7):e0005754. doi: 10.1371/journal.pntd.0005754
66
de Toledo-PintoTGFerreiraABRibeiro-AlvesMRodriguesLSBatista-SilvaLRSilvaBJet al. Sting-Dependent 2’-5’ Oligoadenylate Synthetase-Like Production is Required for Intracellular Mycobacterium Leprae Survival. J Infect Dis (2016) 214(2):311–20. doi: 10.1093/infdis/jiw144
67
Franco-ParedesCRodriguez-MoralesAJ. Unsolved Matters in Leprosy: A Descriptive Review and Call for Further Research. Ann Clin Microbiol Antimicrob (2016) 15(1):33. doi: 10.1186/s12941-016-0149-x
68
Bonilla-AldanaDKAguirre-FlorezMVillamizar-PenaRGutierrez-OcampoEHenao-MartinezJFCvetkovic-VegaAet al. After SARS-CoV-2, Will H5N6 and Other Influenza Viruses Follow the Pandemic Path? Infez Med (2020) 28(4):475–85.
69
PhilipponDAMWuPCowlingBJLauEHY. Avian Influenza Human Infections At the Human-Animal Interface. J Infect Dis (2020) 222(4):528–37. doi: 10.1093/infdis/jiaa105
70
DhamaKChauhanRKatariaJMaheshMSimmiT. Avian Influenza: The Current Perspectives. J Immunol Immunopathol (2005) 7(2):1–33.
71
ChandySMathaiD. Globally Emerging Hantaviruses: An Overview. Indian J Med Microbiol (2017) 35(2):165–75. doi: 10.4103/ijmm.IJMM_16_429
72
KrugerDHFigueiredoLTMSongJ-WKlempaB. Hantaviruses—Globally Emerging Pathogens. J Clin Virol (2015) 64:128–36. doi: 10.1016/j.jcv.2014.08.033
73
EnriaDAPinheiroF. Rodent-Borne Emerging Viral Zoonosis: Hemorrhagic Fevers and Hantavirus Infections in South America. Infect Dis Clinics North America (2000) 14(1):167–84. doi: 10.1016/S0891-5520(05)70223-3
74
ChandSThapaSKonSJohnsonSCPoeschlaEMFranco-ParedesCet al. Hantavirus Infection With Renal Failure and Proteinuria, Colorado, USA, 2019. Emerg Infect Dis (2020) 26(2):383–5. doi: 10.3201/eid2602.191349
75
Escalera-AntezanaJPTorrez-FernandezRMontalvan-PlataDMontenegro-NarvaezCMAviles-SarmientoJLAlvarado-ArnezLEet al. Orthohantavirus Pulmonary Syndrome in Santa Cruz and Tarija, Bolivia, 2018. Int J Infect Dis (2020) 90:145–50. doi: 10.1016/j.ijid.2019.10.021
76
Gomez-MarinJELondonoALCabeza-AcevedoNTorresENavarrete-MoncadaLBuenoOet al. Ocular Toxocariasis in Parasitology Consultation in Quindio, Colombia: Description of Cases and Contact Studies. J Trop Pediatr (2021) 67(1):fmaa096. doi: 10.1093/tropej/fmaa096
77
Rodriguez-MoralesAJBonilla-AldanaDKGallego-ValenciaVGómez-DeLaRosaSHLópez-EcheverriCPeña-VerjanNMet al. Toxocariasis in Colombia: More Than Neglected. Curr Trop Med Rep (2020) 7(1):17–24. doi: 10.1007/s40475-020-00199-x
78
Bonilla-AldanaDKCardona-TrujilloMCGarcia-BarcoAHolguin-RiveraYCortes-BonillaIBedoya-AriasHAet al. Mers-CoV and SARS-CoV Infections in Animals: A Systematic Review and Meta-Analysis of Prevalence Studies. Infez Med (2020) 28(suppl 1):71–83. doi: 10.20944/preprints202003.0103.v1
79
DhamaKPatelSKSharunKPathakMTiwariRYatooMIet al. Sars-CoV-2 Jumping the Species Barrier: Zoonotic Lessons From SARS, MERS and Recent Advances to Combat This Pandemic Virus. Travel Med Infect Dis (2020) 37:101830. doi: 10.1016/j.tmaid.2020.101830
80
RabaanAAAl-AhmedSHHaqueSSahRTiwariRMalikYSet al. SARS-Cov-2, SARS-CoV, and MERS-COV: A Comparative Overview. Infez Med (2020) 28(2):174–84.
81
Bonilla-AldanaDKQuintero-RadaKMontoya-PosadaJPRamirez-OcampoSPaniz-MondolfiARabaanAAet al. SARS-Cov, MERS-CoV and Now the 2019-Novel CoV: Have We Investigated Enough About Coronaviruses? - A Bibliometric Analysis Travel Med Infect Dis (2020) 33:101566. doi: 10.1016/j.tmaid.2020.101566
82
Al-TawfiqJARodriguez-MoralesAJ. Super-Spreading Events and Contribution to Transmission of MERS, SARS, and SARS-CoV-2 (Covid-19). J Hosp Infect (2020) 105(2):111–2. doi: 10.1016/j.jhin.2020.04.002
83
Sanchez-DuqueJAArce-VillalobosLRRodriguez-MoralesAJ. [Coronavirus Disease 2019 (COVID-19) in Latin America: Role of Primary Care in Preparedness and Response]. Aten Primaria (2020) 52(6):369–72. doi: 10.1016/j.aprim.2020.04.001
84
DhamaKKhanSTiwariRSircarSBhatSMalikYSet al. Coronavirus Disease 2019-COVID-19. Clin Microbiol Rev (2020) 33(4):e00028–20. doi: 10.1128/CMR.00028-20
85
HashemNMGonzalez-BulnesARodriguez-MoralesAJ. Animal Welfare and Livestock Supply Chain Sustainability Under the COVID-19 Outbreak: An Overview. Front Vet Sci (2020) 7:582528. doi: 10.3389/fvets.2020.582528
86
Herrera-AnazcoPUyen-CaterianoAMezones-HolguinETaype-RondanAMayta-TristanPMalagaGet al. Some Lessons That Peru did Not Learn Before the Second Wave of COVID-19. Int J Health Plann Manage (2021). doi: 10.1002/hpm.3135
87
Carrillo-HernandezMYRuiz-SaenzJVillamizarLJGomez-RangelSYMartinez-GutierrezM. Co-Circulation and Simultaneous Co-Infection of Dengue, Chikungunya, and Zika Viruses in Patients With Febrile Syndrome At the Colombian-Venezuelan Border. BMC Infect Dis (2018) 18(1):61. doi: 10.1186/s12879-018-2976-1
88
HaqqiAAwanUAAliMSaqibMANAhmedHAfzalMS. Covid-19 and Dengue Virus Coepidemics in Pakistan: A Dangerous Combination for an Overburdened Healthcare System. J Med Virol (2021) 93(1):80–2. doi: 10.1002/jmv.26144
89
Sanchez-DuqueJAOrozco-HernandezJPMarin-MedinaDSCvetkovic-VegaAAveiro-RobaloTRMondragon-CardonaAet al. Are We Now Observing an Increasing Number of Coinfections Between SARS-CoV-2 and Other Respiratory Pathogens? J Med Virol (2020) 92(11):2398–400. doi: 10.1002/jmv.26089
90
AlbercaRWYendoTMLeuzzi RamosYAFernandesIGOliveiraLMTeixeiraFMEet al. Case Report: Covid-19 and Chagas Disease in Two Coinfected Patients. Am J Trop Med Hyg (2020) 103(6):2353–6. doi: 10.4269/ajtmh.20-1185
91
Touzard-RomoFTapeCLonksJR. Co-Infection With SARS-CoV-2 and Human Metapneumovirus. R I Med J (2013) (2020) 103(2):75–6.
92
RodriguezJARubio-GomezHRoaAAMillerNEckardtPA. Co-Infection With SARS-COV-2 and Parainfluenza in a Young Adult Patient With Pneumonia: Case Report. IDCases (2020) 20:e00762. doi: 10.1016/j.idcr.2020.e00762
93
Rodriguez-MoralesAJSuarezJARisquezADelgado-NogueraLPaniz-MondolfiA. The Current Syndemic in Venezuela: Measles, Malaria and More Co-Infections Coupled With a Breakdown of Social and Healthcare Infrastructure. Quo Vadis? Travel Med Infect Dis (2019) 27:5–8. doi: 10.1016/j.tmaid.2018.10.010
94
Villamil-GomezWEGonzalez-CamargoORodriguez-AyubiJZapata-SerpaDRodriguez-MoralesAJ. Dengue, Chikungunya and Zika Co-Infection in a Patient From Colombia. J Infect Public Health (2016) 9(5):684–6. doi: 10.1016/j.jiph.2015.12.002
95
Paniz-MondolfiAERodriguez-MoralesAJBlohmGMarquezMVillamil-GomezWE. Chikdenmazika Syndrome: The Challenge of Diagnosing Arboviral Infections in the Midst of Concurrent Epidemics. Ann Clin Microbiol Antimicrob (2016) 15(1):42. doi: 10.1186/s12941-016-0157-x
96
Villamil-GomezWERodriguez-MoralesAJUribe-GarciaAMGonzalez-ArismendyECastellanosJECalvoEPet al. Zika, Dengue, and Chikungunya Co-Infection in a Pregnant Woman From Colombia. Int J Infect Dis (2016) 51:135–8. doi: 10.1016/j.ijid.2016.07.017
97
Villamil-GomezWERodriguez-MoralesAJ. Reply: Dengue RT-PCR-Positive, Chikungunya IgM-positive and Zika Rt-PCR-positive Co-Infection in a Patient From Colombia. J Infect Public Health (2017) 10(1):133–4. doi: 10.1016/j.jiph.2016.02.003
98
Villamil-GomezWESilveraLAHenao-PalenciaSContreras-ArrietaJCaceresJFOrtiz-MartinezYet al. Coinfection of Trypanosoma Cruzi and Mycobacterium Tuberculosis in a Patient From Colombia. J Infect Public Health (2016) 9(1):113–5. doi: 10.1016/j.jiph.2015.09.004
99
RifakisPMBenitezJARodriguez-MoralesAJDicksonSMDe-La-Paz-PinedaJ. Ecoepidemiological and Social Factors Related to Rabies Incidence in Venezuela During 2002-2004. Int J BioMed Sci (2006) 2(1):1–6.
100
MacleodCKBrightPSteerACKimJMabeyDParksT. Neglecting the Neglected: The Objective Evidence of Underfunding in Rheumatic Heart Disease. Trans R Soc Trop Med Hyg (2019) 113(5):287–90. doi: 10.1093/trstmh/trz014
101
Rodriguez-MoralesAJSánchez-DuqueJAHernández-BoteroSPérez-DíazCEVillamil-GómezWEMéndezCAet al. Preparación Y Control De La Enfermedad Por Coronavirus 2019 (COVID-19) En América Latina. Acta Med Peruana (2020) 37(1):3–7. doi: 10.35663/amp.2020.371.909
102
PathakMPatelSKJigyasaRTiwariRDhamaKSahRet al. Global Threat of SARS-CoV-2/COVID-19 and the Need for More and Better Diagnostic Tools. Arch Med Res (2020) 51(5):450–2. doi: 10.1016/j.arcmed.2020.04.003
103
MousaviSHZahidSUWardakKAzimiKAReza HosseiniSMWafaeeMet al. Mapping the Changes on Incidence, Case Fatality Rates and Recovery Proportion of COVID-19 in Afghanistan Using Geographical Information Systems. Arch Med Res (2020) 51(6):600–2. doi: 10.1016/j.arcmed.2020.06.010
104
CimermanSChebaboACunhaCADRodriguez-MoralesAJ. Deep Impact of COVID-19 in the Healthcare of Latin America: The Case of Brazil. Braz J Infect Dis (2020) 24(2):93–5. doi: 10.1016/j.bjid.2020.04.005
105
Rodriguez-MoralesAJRodriguez-MoralesAGMendezCAHernandez-BoteroS. Tracing New Clinical Manifestations in Patients With COVID-19 in Chile and Its Potential Relationship With the SARS-CoV-2 Divergence. Curr Trop Med Rep (2020) 7:75–8. doi: 10.1007/s40475-020-00205-2
106
Bonilla-AldanaDKVillamil-GómezWERabaanAARodriguez-MoralesAJ. Una Nueva Zoonosis Viral De Preocupación Global: COVID-19, Enfermedad Por Coronavirus 2019. Iatreia (2020) 33(2):107–10. doi: 10.17533/udea.iatreia.85
107
Rodriguez-MoralesAJBalbin-RamonGJRabaanAASahRDhamaKPaniz-MondolfiAet al. Genomic Epidemiology and its Importance in the Study of the COVID-19 Pandemic. Infez Med (2020) 28(2):139–42.
108
AhmadTKhanMHaroonMusaTHNasirSHuiJet al. Covid-19: Zoonotic Aspects. Travel Med Infect Dis (2020) 36:101607. doi: 10.1016/j.tmaid.2020.101607
109
Escalera-AntezanaJPLizon-FerrufinoNFMaldonado-AlanocaAAlarcon-De-la-VegaGAlvarado-ArnezLEBalderrama-SaavedraMAet al. Clinical Features of the First Cases and a Cluster of Coronavirus Disease 2019 (Covid-19) in Bolivia Imported From Italy and Spain. Travel Med Infect Dis (2020) 35:101653. doi: 10.1016/j.tmaid.2020.101653
110
Rodriguez-MoralesAJCardona-OspinaJAGutierrez-OcampoEVillamizar-PenaRHolguin-RiveraYEscalera-AntezanaJPet al. Clinical, Laboratory and Imaging Features of COVID-19: A Systematic Review and Meta-Analysis. Travel Med Infect Dis (2020) 34:101623. doi: 10.1016/j.tmaid.2020.101623
111
Rodriguez-MoralesAJGallegoVEscalera-AntezanaJPMendezCAZambranoLIFranco-ParedesCet al. Covid-19 in Latin America: The Implications of the First Confirmed Case in Brazil. Travel Med Infect Dis (2020) 35:101613. doi: 10.1016/j.tmaid.2020.101613
112
AhmadTHaroonDhamaKSharunKFMKAhmedIet al. Biosafety and Biosecurity Approaches to Restrain/Contain and Counter SARS-CoV-2/ Covid-19 Pandemic: A Rapid-Review. Turk J Biol (2020) 44(Special issue 1):132–45. doi: 10.3906/biy-2005-63
113
NurainiNFauziISFakhruddinMSopaheluwakanASoewonoE. Climate-Based Dengue Model in Semarang, Indonesia: Predictions and Descriptive Analysis. Infect Dis Model (2021) 6:598–611. doi: 10.1016/j.idm.2021.03.005
114
HussenMOSayedASMAbushahbaMFN. Sero-Epidemiological Study on Dengue Fever Virus in Humans and Camels At Upper Egypt. Vet World (2020) 13(12):2618–24. doi: 10.14202/vetworld.2020.2618-2624
115
RyanSJCarlsonCJMordecaiEAJohnsonLR. Global Expansion and Redistribution of Aedes-borne Virus Transmission Risk With Climate Change. PloS Negl Trop Dis (2019) 13(3):e0007213. doi: 10.1371/journal.pntd.0007213
116
Alarcon-ElbalPMRodriguez-SosaMANewmanBCSuttonWB. The First Record of Aedes Vittatus (Diptera: Culicidae) in the Dominican Republic: Public Health Implications of a Potential Invasive Mosquito Species in the Americas. J Med Entomol (2020) 57(6):2016–21. doi: 10.1093/jme/tjaa128
117
ChowdhuryFRIbrahimQSUBariMSAlamMMJDunachieSJRodriguez-MoralesAJet al. The Association Between Temperature, Rainfall and Humidity With Common Climate-Sensitive Infectious Diseases in Bangladesh. PloS One (2018) 13(6):e0199579. doi: 10.1371/journal.pone.0199579
118
Rodriguez-MoralesAJ. Climate Change, Climate Variability and Brucellosis. Recent Pat Antiinfect Drug Discovery (2013) 8(1):4–12. doi: 10.2174/1574891X11308010003
119
Rodriguez-MoralesAJ. [Climate Change, Rainfall, Society and Disasters in Latin America: Relations and Needs]. Rev Peru Med Exp Salud Publica (2011) 28(1):165–6. doi: 10.1590/S1726-46342011000100032
120
ChowdhuryFRIbrahimQSUBariMSAlamMMJDunachieSJRodriguez-MoralesAJet al. Correction: The Association Between Temperature, Rainfall and Humidity With Common Climate-Sensitive Infectious Diseases in Bangladesh. PloS One (2020) 15(4):e0232285. doi: 10.1371/journal.pone.0232285
121
MattarSMoralesVCassabARodriguez-MoralesAJ. Effect of Climate Variables on Dengue Incidence in a Tropical Caribbean Municipality of Colombia, Cerete, 2003-2008. Int J Infect Dis (2013) 17(5):e358–9. doi: 10.1016/j.ijid.2012.11.021
122
CardenasRSandovalCMRodriguez-MoralesAJFranco-ParedesC. Impact of Climate Variability in the Occurrence of Leishmaniasis in Northeastern Colombia. Am J Trop Med Hyg (2006) 75(2):273–7. doi: 10.4269/ajtmh.2006.75.273
123
ZambranoLISevillaCReyes-GarciaSZSierraMKafatiRRodriguez-MoralesAJet al. Potential Impacts of Climate Variability on Dengue Hemorrhagic Fever in Honduras, 2010. Trop BioMed (2012) 29(4):499–507.
124
Herrera-MartinezADRodriguez-MoralesAJ. Potential Influence of Climate Variability on Dengue Incidence Registered in a Western Pediatric Hospital of Venezuela. Trop BioMed (2010) 27(2):280–6.
125
CardenasRSandovalCMRodriguez-MoralesAJVivasP. Zoonoses and Climate Variability. Ann N Y Acad Sci (2008) 1149:326–30. doi: 10.1196/annals.1428.094
126
Rodriguez-MoralesAJSimonF. Chronic Chikungunya, Still to be Fully Understood. Int J Infect Dis (2019) 86:133–4. doi: 10.1016/j.ijid.2019.07.024
127
Rodriguez-MoralesAJCardona-OspinaJAVillamil-GomezWPaniz-MondolfiAE. How Many Patients With Post-Chikungunya Chronic Inflammatory Rheumatism can We Expect in the New Endemic Areas of Latin America? Rheumatol Int (2015) 35(12):2091–4. doi: 10.1007/s00296-015-3302-5
128
Rodriguez-MoralesAJRestrepo-PosadaVMAcevedo-EscalanteNRodriguez-MunozEDValencia-MarinMCastrillon-SpitiaJDet al. Impaired Quality of Life After Chikungunya Virus Infection: A 12-Month Follow-Up Study of its Chronic Inflammatory Rheumatism in La Virginia, Risaralda, Colombia. Rheumatol Int (2017) 37(10):1757–8. doi: 10.1007/s00296-017-3795-1
129
Rodriguez-MoralesAJ. Letter to the Editor: Chikungunya Virus Infection-an Update on Chronic Rheumatism in Latin America. Rambam Maimonides Med J (2017) 8(1):e0013. doi: 10.5041/RMMJ.10288
130
Rodriguez-MoralesAJVillamil-GomezWMerlano-EspinosaMSimone-KleberL. Post-Chikungunya Chronic Arthralgia: A First Retrospective Follow-Up Study of 39 Cases in Colombia. Clin Rheumatol (2016) 35(3):831–2. doi: 10.1007/s10067-015-3041-8
131
Rodriguez-MoralesAJCalvache-BenavidesCEGiraldo-GomezJHurtado-HurtadoNYepes-EcheverriMCGarcia-LoaizaCJet al. Post-Chikungunya Chronic Arthralgia: Results From a Retrospective Follow-Up Study of 131 Cases in Tolima, Colombia. Travel Med Infect Dis (2016) 14(1):58–9. doi: 10.1016/j.tmaid.2015.09.001
132
Rodriguez-MoralesAJGil-RestrepoAFRamirez-JaramilloVMontoya-AriasCPAcevedo-MendozaWFBedoya-AriasJEet al. Post-Chikungunya Chronic Inflammatory Rheumatism: Results From a Retrospective Follow-Up Study of 283 Adult and Child Cases in La Virginia, Risaralda, Colombia. F1000Res (2016) 5:360. doi: 10.12688/f1000research.8235.2
133
Alvarado-SocarrasJLIdrovoAJContreras-GarciaGARodriguez-MoralesAJAudcentTAMogollon-MendozaACet al. Congenital Microcephaly: A Diagnostic Challenge During Zika Epidemics. Travel Med Infect Dis (2018) 23:14–20. doi: 10.1016/j.tmaid.2018.02.002
134
Rodriguez-MoralesAJCardona-OspinaJARamirez-JaramilloVGaviriaJAGonzalez-MorenoGMCastrillon-SpitiaJDet al. Diagnosis and Outcomes of Pregnant Women With Zika Virus Infection in Two Municipalities of Risaralda, Colombia: Second Report of the ZIKERNCOL Study. Travel Med Infect Dis (2018) 25:20–5. doi: 10.1016/j.tmaid.2018.06.006
135
Alvarado-SocarrasJLAux-CadenaCPMurillo-GarciaDRRodriguez-MoralesAJ. Ophthalmologic Evaluation in Infants of Mothers With Zika: A Report From Colombia. Travel Med Infect Dis (2019) 32:101449. doi: 10.1016/j.tmaid.2019.07.005
136
WijeratneTCrewtherS. Covid-19 and Long-Term Neurological Problems: Challenges Ahead With Post-COVID-19 Neurological Syndrome. Aust J Gen Pract (2021) 50. doi: 10.31128/AJGP-COVID-43
137
ChunHJCoutavasEPineALeeAIYuVShallowMet al. Immuno-Fibrotic Drivers of Impaired Lung Function in post-COVID-19 Syndrome. medRxiv (2021). doi: 10.1101/2021.01.31.21250870
138
SorianoJBWatererGPenalvoJLRelloJ. Nefer, Sinuhe and Clinical Research Assessing post-COVID-19 Syndrome. Eur Respir J (2021). doi: 10.1183/13993003.04423-2020
139
BorgKStamHJ. Rehabilitation of post-Covid - 19 Syndrome - Once Again a Call for Action! J Rehabil Med (2021) 53(1):jrm00132. doi: 10.2340/16501977-2783
140
WalshDPMaTFIpHSZhuJ. Artificial Intelligence and Avian Influenza: Using Machine Learning to Enhance Active Surveillance for Avian Influenza Viruses. Transbound Emerg Dis (2019) 66(6):2537–45. doi: 10.1111/tbed.13318
141
ThiebautRCossinS. Section Editors for the IYSoPH, Epidemiology I. Artificial Intelligence for Surveillance in Public Health. Yearb Med Inform (2019) 28(1):232–4. doi: 10.1055/s-0039-1677939
142
ChiappelliFBalentonNKhakshooyA. Future Innovations in Viral Immune Surveillance: A Novel Place for Bioinformation and Artificial Intelligence in the Administration of Health Care. Bioinformation (2018) 14(5):201–5. doi: 10.6026/97320630014201
143
Cardona-OspinaJARojas-GallardoDMGarzon-CastanoSCJimenez-PosadaEVRodriguez-MoralesAJ. Phylodynamic Analysis in the Understanding of the Current COVID-19 Pandemic and its Utility in Vaccine and Antiviral Design and Assessment. Hum Vaccin Immunother (2021), 1–8. doi: 10.1080/21645515.2021.1880254
144
RabaanAAAl-AhmedSHSahRAl-TawfiqJAHaqueSHarapanHet al. Genomic Epidemiology and Recent Update on Nucleic Acid-Based Diagnostics for COVID-19. Curr Trop Med Rep (2020) 7:113–9. doi: 10.1007/s40475-020-00212-3
145
AugusteAJLemeyPBergrenNAGiambalvoDMoncadaMMoronDet al. Enzootic Transmission of Yellow Fever Virus, Venezuela. Emerg Infect Dis (2015) 21(1):99–102. doi: 10.3201/eid2101.140814
146
SolanoDNavarroJCLeon-ReyesABenitez-OrtizWRodriguez-HidalgoR. Molecular Analyses Reveal Two Geographic and Genetic Lineages for Tapeworms, Taenia Solium and Taenia Saginata, From Ecuador Using Mitochondrial DNA. Exp Parasitol (2016) 171:49–56. doi: 10.1016/j.exppara.2016.10.015
147
Rendon-MarinSMartinez-GutierrezMWhittakerGRJaimesJARuiz-SaenzJ. Sars CoV-2 Spike Protein in Silico Interaction With ACE2 Receptors From Wild and Domestic Species. Front Genet (2021) 12(27):571707. doi: 10.3389/fgene.2021.571707
148
ElsingaJGrobuschMPTamiAGerstenbluthIBaileyA. Health-Related Impact on Quality of Life and Coping Strategies for Chikungunya: A Qualitative Study in Curacao. PloS Negl Trop Dis (2017) 11(10):e0005987. doi: 10.1371/journal.pntd.0005987
149
ProosRMatheronHVas NunesJFalamaASery KamalPGrobuschMPet al. Perspectives of Health Workers on the Referral of Women With Obstetric Complications: A Qualitative Study in Rural Sierra Leone. BMJ Open (2020) 10(12):e041746. doi: 10.1136/bmjopen-2020-041746
150
PortaM. A Dictionary of Epidemiology: Books.Google.Com. International Association of Epidemiology and Oxford Press (2014). doi: 10.1093/acref/9780199976720.001.0001
151
Rodríguez-MoralesAJ. Ecoepidemiología Y Epidemiología Satelital: Nuevas Herramientas En El Manejo De Problemas En Salud Pública. Rev Peruana Medicina Exp y Salud Publica (2005) 22:54–63.
152
BrendeBFarrarJGashumbaDMoedasCMundelTShiozakiYet al. CEPI-a New Global R&D Organisation for Epidemic Preparedness and Response. Lancet (2017) 389(10066):233–5. doi: 10.1016/S0140-6736(17)30131-9
153
GouglasDChristodoulouMPlotkinSAHatchettR. Cepi: Driving Progress Toward Epidemic Preparedness and Response. Epidemiol Rev (2019) 41(1):28–33. doi: 10.1093/epirev/mxz012
154
PlotkinSA. Vaccines for Epidemic Infections and the Role of CEPI. Hum Vaccin Immunother (2017) 13(12):2755–62. doi: 10.1080/21645515.2017.1306615
155
de Sousa PereiraHScofieldAJuniorPSBLira Dos SantosDde Sousa SiqueiraJChavesJFet al. Chagas Disease in Urban and Periurban Environment in the Amazon: Sentinel Hosts, Vectors, and the Environment. Acta Trop (2021) 217:105858. doi: 10.1016/j.actatropica.2021.105858
156
BastosCJArasRMotaGReisFDiasJPde JesusRSet al. Clinical Outcomes of Thirteen Patients With Acute Chagas Disease Acquired Through Oral Transmission From Two Urban Outbreaks in Northeastern Brazil. PloS Negl Trop Dis (2010) 4(6):e711. doi: 10.1371/journal.pntd.0000711
157
Shikanai-YasudaMACarvalhoNB. Oral Transmission of Chagas Disease. Clin Infect Dis (2012) 54(6):845–52. doi: 10.1093/cid/cir956
158
NoyaBAPerez-ChaconGDiaz-BelloZDicksonSMunoz-CalderonAHernandezCet al. Description of an Oral Chagas Disease Outbreak in Venezuela, Including a Vertically Transmitted Case. Mem Inst Oswaldo Cruz (2017) 112(8):569–71. doi: 10.1590/0074-02760170009
159
DiazMLLealSMantillaJCMolina-BerriosALopez-MunozRSolariAet al. Acute Chagas Outbreaks: Molecular and Biological Features of Trypanosoma Cruzi Isolates, and Clinical Aspects of Acute Cases in Santander, Colombia. Parasit Vectors (2015) 8:608. doi: 10.1186/s13071-015-1218-2
160
RuedaKTrujilloJECarranzaJCVallejoGA. [Oral Transmission of Trypanosoma Cruzi : A New Epidemiological Scenario for Chagas’ Disease in Colombia and Other South American Countries]. Biomedica (2014) 34(4):631–41. doi: 10.7705/biomedica.v34i4.2204
161
LacerdaAFAOliveriaDSSalomaoJVFOliveiraLGRMonte-AlegreASantosJet al. Clinical, Epidemiological and Transmission Cycle Aspects of Leishmaniasis Urbanization in Barreiras, Bahia, Brazil. Spat Spatiotemporal Epidemiol (2021) 36:100395. doi: 10.1016/j.sste.2020.100395
162
da Silva Santana CruzCSoeiro BarbosaDOliveiraVCCardosoDTGuimaraesNSCarneiroM. Factors Associated With Human Visceral Leishmaniasis Cases During Urban Epidemics in Brazil: A Systematic Review. Parasitology (2021) 148(6):639–47. doi: 10.1017/S0031182021000019
163
RibeiroCJNDos SantosADLimaSda SilvaERRibeiroBVSDuqueAMet al. Space-Time Risk Cluster of Visceral Leishmaniasis in Brazilian Endemic Region With High Social Vulnerability: An Ecological Time Series Study. PloS Negl Trop Dis (2021) 15(1):e0009006. doi: 10.1371/journal.pntd.0009006
164
Zambrano-HernandezPAyala-SoteloMSFuya-OviedoPMontenegro-PuentesCAAya-VanegasNMAguilera-JaramilloGet al. [Urban Outbreak of Visceral Leishmaniasis in Neiva (Colombia)]. Rev Salud Publica (Bogota) (2015) 17(4):514–27. doi: 10.15446/rsap.v17n4.44663
165
Osorio-PinzonJPalenciaACruz-CalderonSRodriguez-MoralesAJ. Myiasis and Tungiasis. Curr Trop Med Rep (2021). doi: 10.1007/s40475-021-00233-6
166
ShepardZRiosMSolisJWandTHenao-MartínezAFFranco-ParedesCet al. Common Dermatologic Conditions in Returning Travelers. Curr Trop Med Rep (2021). doi: 10.1007/s40475-021-00231-8
167
PecchioMSuarezJAHesseSHershAMGundackerND. Descriptive Epidemiology of Snakebites in the Veraguas Province of Panama, 2007-2008. Trans R Soc Trop Med Hyg (2018) 112(10):463–6. doi: 10.1093/trstmh/try076
168
Reyes-LugoMSanchezTFinolHJSanchezEESuarezJAGuerreiroBet al. Neurotoxic Activity and Ultrastructural Changes in Muscles Caused by the Brown Widow Spider Latrodectus Geometricus Venom. Rev Inst Med Trop Sao Paulo (2009) 51(2):95–101. doi: 10.1590/S0036-46652009000200007
169
BenitezJARifakisPMVargasJACabanielGRodriguez-MoralesAJ. Trends in Fatal Snakebites in Venezuela, 1995-2002. Wilderness Environ Med (2007) 18(3):209–13. doi: 10.1580/06-WEME-BR-076R.1
170
De RoodtARSalomonODLloverasSCOrdunaTA. [Poisoning by Spiders of Loxosceles Genus]. Medicina (B Aires) (2002) 62(1):83–94.
171
Bonilla-AldanaDKSuarezJAFranco-ParedesCVilcarromeroSMattarSGomez-MarinJEet al. Brazil Burning! What is the Potential Impact of the Amazon Wildfires on Vector-Borne and Zoonotic Emerging Diseases? - A Statement From an International Experts Meeting. Travel Med Infect Dis (2019) 31:101474. doi: 10.1016/j.tmaid.2019.101474
172
Bonilla-AldanaDKHolguin-RiveraYPerez-VargasSTrejos-MendozaAEBalbin-RamonGJDhamaKet al. Importance of the One Health Approach to Study the SARS-CoV-2 in Latin America. One Health (2020) 10:100147. doi: 10.1016/j.onehlt.2020.100147
Summary
Keywords
vector-borne diseases, zoonotic diseases, emerging, SARS-CoV-2/COVID-2, tropical diseases, challenges
Citation
Rodriguez-Morales AJ, Paniz-Mondolfi AE, Faccini-Martínez ÁA, Henao-Martínez AF, Ruiz-Saenz J, Martinez-Gutierrez M, Alvarado-Arnez LE, Gomez-Marin JE, Bueno-Marí R, Carrero Y, Villamil-Gomez WE, Bonilla-Aldana DK, Haque U, Ramirez JD, Navarro J-C, Lloveras S, Arteaga-Livias K, Casalone C, Maguiña JL, Escobedo AA, Hidalgo M, Bandeira AC, Mattar S, Cardona-Ospina JA and Suárez JA (2021) The Constant Threat of Zoonotic and Vector-Borne Emerging Tropical Diseases: Living on the Edge. Front. Trop. Dis 2:676905. doi: 10.3389/fitd.2021.676905
Received
06 March 2021
Accepted
06 April 2021
Published
04 May 2021
Volume
2 - 2021
Edited and reviewed by
Jerome Kim, International Vaccine Institute, South Korea
Updates
Copyright
© 2021 Rodriguez-Morales, Paniz-Mondolfi, Faccini-Martínez, Henao-Martínez, Ruiz-Saenz, Martinez-Gutierrez, Alvarado-Arnez, Gomez-Marin, Bueno-Marí, Carrero, Villamil-Gomez, Bonilla-Aldana, Haque, Ramirez, Navarro, Lloveras, Arteaga-Livias, Casalone, Maguiña, Escobedo, Hidalgo, Bandeira, Mattar, Cardona-Ospina and Suárez.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Alfonso J. Rodriguez-Morales, alfonso.rodriguez@uam.edu.co
This article was submitted to Emerging Tropical Diseases, a section of the journal Frontiers in Tropical Diseases
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