REVIEW article
Front. Tuberc.
Sec. Immunological Basis of Tuberculosis
Volume 3 - 2025 | doi: 10.3389/ftubr.2025.1531298
Insights into the epidemiological connections and hypotheses on the association between Takayasu Arteritis and Mycobacterium tuberculosis infection
Provisionally accepted- 1Universidad La Salle, Ciudad de México, Mexico
- 2Universidad La Salle, Mexico City, México, Mexico
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Takayasu arteritis is a rare but devastating disease that affects the main arteries, and its fatal outcomes usually occur due to compromised blood flow. Takayasu arteritis has been the subject of multiple questions, and Mycobacterium tuberculosis has been pointed out as a possible causal agent of this disease. The importance of this study lies in the presentation of the multiple hypotheses that support or discredit the relationship between the two, highlighting the epidemiological qualities of each one in the world and in particular countries, which could be crucial for decision-making and for future research regarding its management. This review offers valuable information about the epidemiology in the world, not only of Takayasu arteritis but of Tuberculosis, which allows for the expansion of knowledge on the subject. By addressing the intersection between infectious diseases and autoimmune vasculitis, this work aligns with the scope of Frontiers in Medicine -Rheumatology. The manuscript provides a rheumatological perspective on the potential infectious triggers of Takayasu arteritis, contributing to a deeper understanding of its pathogenesis and epidemiology, which are core interests of this section.
Keywords: Alejandra Roa-León: Formal Analysis, investigation, methodology, Validation, Writing -original draft, Writing -review & editing. Diana Elisa Morales Sánchez: Conceptualization, Formal analysis, project administration
Received: 22 Nov 2024; Accepted: 26 Jun 2025.
Copyright: © 2025 Sernas-Mendoza, Morales Sánchez, Plata Reyes and Roa-León. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Kevin Sernas-Mendoza, Universidad La Salle, Ciudad de México, Mexico
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