Frontiers in Tuberculosis

Review

Published on 28 Oct 2026

Macrophage-state heterogeneity as the basis for host-directed therapy in tuberculosis

in Pathogen and Host Biology of Tuberculosis

Mohd Shariq
Nasreen Zafar Ehtesham
Seyed Ehtesham Hasnain

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1969123

2,081 views

Original Research

Published on 27 Oct 2026

Rationally tailored antibiotic selection circumvents toxin-mediated evasion of killing in Mycobacterium abscessus

in Non-Tuberculous Mycobacteria

Nikita H. Amin
Eduardo A. Troian
Nancy A. Woychik

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1921029

927 views

Review

Accepted on 26 Oct 2026

Tuberculosis vaccines: unresolved immunologic questions in the search for protective immunity

in Immunological Basis of Tuberculosis

Patrick K Moonan
Stephen Mathew
Stephen E Weis
Timothy H Holtz
Samuel Maurice Behar
Uma Devi Ranganathan
Jerry William Simecka

Frontiers in Tuberculosis

244 views

Original Research

Accepted on 23 Oct 2026

GENETIC BLUEPRINTS: CYTOKINE AND CHEMOKINE VARIANTS ASSOCIATED WITH TB PROGRESSION

in Immunological Basis of Tuberculosis

Evangeline Ann Daniel
Manohar Nesakumar
Kannan Thiruvengadam
Nancy Hilda Joseph
Ramesh Karunaianantham
Padmapriyadarsini Chandrasekaran
Sathyamurthi Pattabiraman
BRINDHA BHANU
Amsaveni Sivaprakasam
Mandar Paradkar

Frontiers in Tuberculosis

711 views

Editorial

Published on 20 Oct 2026

Editorial: Advances in the understanding and management of non-tuberculous mycobacteria infections

in Non-Tuberculous Mycobacteria

Anil K. Ojha
Laurent Kremer

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.2012273

419 views

Original Research

Published on 12 Oct 2026

Translating drug-resistant tuberculosis surveillance into molecular–biophotonic diagnostic innovation in rural Eastern Cape, South Africa

in Epidemiology of Tuberculosis

Ncomeka Sineke
Kamvelihle Sabisa
Ntandazo Dlatu
Saturnin Ombinda-Lemboumba
Teke Apalata
Lindiwe Modest Faye

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1937755

662 views

Original Research

Published on 09 Oct 2026

Spondylodiscitis in a tuberculosis-endemic setting in Somalia: epidemiological, clinical, radiological, and outcome findings from a retrospective study

in Epidemiology of Tuberculosis

Hussein Salad Yusuf
Abdirisak Ali Abukar
Mohamed Said Adan
Abdiaziz Siad Mohamed
Zakariye Yusuf Mohamed
Mustaf Abdi Ulusow
Mohamed Osman Dahir Alasow
Abdiwahid Ahmed Ibrahim
Naimo Awil Dahir

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1971442

638 views

Review

Published on 08 Oct 2026

Nutrition, thyroid function, and tuberculosis: exploring the endocrine–immune axis

in Pathogen and Host Biology of Tuberculosis

Nooneh Khachatourian
Rubina Takhmazian
Vishwanath Venketaraman

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1945832

816 views

Original Research

Published on 02 Oct 2026

High-throughput screening to identify inhibitors of the MTB CARD•RNA polymerase protein-protein interaction

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Glory M. Velazquez
Jonathan Z. Sexton
Scott G. Franzblau
Gauri S. Shetye
Akil Hossain
George A. Garcia

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1937953

910 views

Review

Published on 06 Aug 2026

Secreted proteins of Mycobacterium tuberculosis as therapeutic targets for drug discovery

in Pathogen and Host Biology of Tuberculosis

Anthony Musaazi Kaweesa
Divya Tiwari

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1736139

1,539 views

Original Research

Published on 06 Aug 2026

Adjunctive antimycobacterial and immunomodulatory effects of Allium cepa (pink variety) in a rabbit model of latent-like mycobacterial infection

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Theophilus Kwesi Ninkyi
Eric Ogyam
Kelvin Atta Agyapong
Cynthia Amaning Danquah

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1874315

814 views

Original Research

Published on 15 Jul 2026

A Mycobacterium tuberculosis rare variable antigen vaccine reduces lung pathology in hypersusceptible SP140−/− mice

in Immunological Basis of Tuberculosis

Zachary P. Howard
Alexander Mohapatra
Weihao Zheng
Joel D. Ernst

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1814646

1,377 views

Brief Research Report

Published on 02 Jul 2026

Implementation of sequencing-based surveillance for drug-resistant tuberculosis in Nigeria

in Diagnosis of Tuberculosis

Heather P. McLaughlin
Israel Audu
Monday Tola
Chika Kingsley Onwuamah
Julius Ogwu
Kenneth Atoe
Chioma Nneka Kunle-Ope
Isiyaku Ahmadu
Joshua Gowon
David B. Meshak

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1855903

1,373 views

Original Research

Published on 30 Jun 2026

The AcasR-FadD9 regulatory axis modulates iron homeostasis and susceptibility to the anti-mycobacterial compound ACA

in Pathogen and Host Biology of Tuberculosis

Feng Huang
Zixin Wang
Dong Jiang
Shengyi Li
Zheng-Guo He
Hua Zhang

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1830528

980 views

Original Research

Published on 25 Jun 2026

Using interpretable decision trees to explore TB-HIV integration under data constraints: a proof-of-concept analysis

in Epidemiology of Tuberculosis

Ntandazo Dlatu
Lindiwe Modest Faye
Mojisola Clara Hosu
Teke Apalata

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1853414

1,120 views
1 citation

Original Research

Published on 18 Jun 2026

Identification of novel DNA gyrase B inhibitors in Mycobacterium species using integrated computational approaches

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Jagritee Yadav
Lalhmangaihzuali
Harish Shukla
Anshuman Chandra
Sudhir Kumar Singh
Meenakshi Singh

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1854329

1,878 views
2 citations

Original Research

Published on 11 Jun 2026

Differential roles of resident lung macrophages during control of murine alveolar and airway Mycobacterium abscessus infection

in Non-Tuberculous Mycobacteria

Kelsey C. Haist
Jack H. Congel
Jodi M. Corley
Alma E. Ochoa
Jazalle McClendon
Patrick S. Hume
Jerry A. Nick
William J. Janssen
Kenneth C. Malcolm
Katherine B. Hisert

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1781507

1,592 views
1 citation

Original Research

Published on 11 Jun 2026

Genomic characterization of drug-resistant Mycobacterium tuberculosis complex in western Kenya reveals predominance of isoniazid resistance and discordance with routine susceptibility testing

in Diagnosis of Tuberculosis

Susan Musau
Susan Odera
Victor Moses Musyoki
Eleanor I. Lamont
Noel Onyango
Bob Morrison
Wilfred Murithi
Steve Wandiga
Videlis Nduba
David Sherman

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1855780

1,529 views
1 citation

Original Research

Published on 05 Jun 2026

Sigma factor M induces an ESX-4-focused regulon in Mycobacterium abscessus

in Non-Tuberculous Mycobacteria

Jill G. Canestrari
Shawn Gianola
Keith M. Derbyshire
Todd A. Gray

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1797268

1,701 views

Original Research

Published on 29 May 2026

Non-tuberculous mycobacteria pulmonary disease in Texas: an analysis of 8 years of hospital discharge data

in Non-Tuberculous Mycobacteria

Alex Baham
Jotam G. Pasipanodya
Devanshi Mehta
Susan McBride
Shashikant Srivastava

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1740382

1,788 views

Review

Published on 26 May 2026

Research overview—2025: integrating scientific progress to accelerate global tuberculosis elimination

in Epidemiology of Tuberculosis

Patrick K. Moonan
Timothy H. Holtz

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1805962

3,462 views
1 citation

Perspective

Published on 23 Apr 2026

Readiness assessment as a strategy, not an afterthought: leveraging implementation science to integrate tuberculosis comorbidity care in Pakistan's health system

in Epidemiology of Tuberculosis

Saima Aleem
Zohaib Khan
Bilal Ahmad Khan
Zala
Saima Afaq

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1809118

1,986 views

Original Research

Published on 17 Apr 2026

Evaluation of the performance of promising host transcriptional biosignatures in predicting TB progression during a 1-year prospective cohort study in Indian household contacts

in Diagnosis of Tuberculosis

Synne Jenum
Steffen Hadasch
Dhanasekaran Sivakumaran
Christina Skår Saghaug
Jonas Høgberg
Kasama Chusang Larsen
Sumithra Selvan
Helene Larsen
Christian Ritz
Harleen M. S. Grewal

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1750007

1,844 views

Original Research

Published on 10 Apr 2026

Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity

in Immunological Basis of Tuberculosis

Vaishnavi Kaipilyawar
Samantha Leong
Arianne Lovey
Lorenzzo L. Stringari
Reynaldo Dietze
Jerrold J. Ellner
Rodrigo Ribeiro-Rodrigues
Padmini Salgame

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1783887

2,501 views

83 articles

articles

Macrophage-state heterogeneity as the basis for host-directed therapy in tuberculosis

Rationally tailored antibiotic selection circumvents toxin-mediated evasion of killing in Mycobacterium abscessus

Tuberculosis vaccines: unresolved immunologic questions in the search for protective immunity

GENETIC BLUEPRINTS: CYTOKINE AND CHEMOKINE VARIANTS ASSOCIATED WITH TB PROGRESSION

Editorial: Advances in the understanding and management of non-tuberculous mycobacteria infections

Translating drug-resistant tuberculosis surveillance into molecular–biophotonic diagnostic innovation in rural Eastern Cape, South Africa

Spondylodiscitis in a tuberculosis-endemic setting in Somalia: epidemiological, clinical, radiological, and outcome findings from a retrospective study

Nutrition, thyroid function, and tuberculosis: exploring the endocrine–immune axis

High-throughput screening to identify inhibitors of the MTB CARD•RNA polymerase protein-protein interaction

Secreted proteins of Mycobacterium tuberculosis as therapeutic targets for drug discovery

Adjunctive antimycobacterial and immunomodulatory effects of Allium cepa (pink variety) in a rabbit model of latent-like mycobacterial infection

A Mycobacterium tuberculosis rare variable antigen vaccine reduces lung pathology in hypersusceptible SP140−/− mice

Implementation of sequencing-based surveillance for drug-resistant tuberculosis in Nigeria

The AcasR-FadD9 regulatory axis modulates iron homeostasis and susceptibility to the anti-mycobacterial compound ACA

Using interpretable decision trees to explore TB-HIV integration under data constraints: a proof-of-concept analysis

Identification of novel DNA gyrase B inhibitors in Mycobacterium species using integrated computational approaches

Differential roles of resident lung macrophages during control of murine alveolar and airway Mycobacterium abscessus infection

Genomic characterization of drug-resistant Mycobacterium tuberculosis complex in western Kenya reveals predominance of isoniazid resistance and discordance with routine susceptibility testing

Sigma factor M induces an ESX-4-focused regulon in Mycobacterium abscessus

Non-tuberculous mycobacteria pulmonary disease in Texas: an analysis of 8 years of hospital discharge data

Research overview—2025: integrating scientific progress to accelerate global tuberculosis elimination

Readiness assessment as a strategy, not an afterthought: leveraging implementation science to integrate tuberculosis comorbidity care in Pakistan's health system

Evaluation of the performance of promising host transcriptional biosignatures in predicting TB progression during a 1-year prospective cohort study in Indian household contacts

Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity