Frontiers in Tuberculosis

Review

Published on 06 Aug 2026

Secreted proteins of Mycobacterium tuberculosis as therapeutic targets for drug discovery

in Pathogen and Host Biology of Tuberculosis

Anthony Musaazi Kaweesa
Divya Tiwari

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1736139

123 views

Original Research

Published on 06 Aug 2026

Adjunctive antimycobacterial and immunomodulatory effects of Allium cepa (pink variety) in a rabbit model of latent-like mycobacterial infection

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Theophilus Kwesi Ninkyi
Eric Ogyam
Kelvin Atta Agyapong
Cynthia Amaning Danquah

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1874315

122 views

Original Research

Published on 15 Jul 2026

A Mycobacterium tuberculosis rare variable antigen vaccine reduces lung pathology in hypersusceptible SP140−/− mice

in Immunological Basis of Tuberculosis

Zachary P. Howard
Alexander Mohapatra
Weihao Zheng
Joel D. Ernst

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1814646

522 views

Brief Research Report

Published on 02 Jul 2026

Implementation of sequencing-based surveillance for drug-resistant tuberculosis in Nigeria

in Diagnosis of Tuberculosis

Heather P. McLaughlin
Israel Audu
Monday Tola
Chika Kingsley Onwuamah
Julius Ogwu
Kenneth Atoe
Chioma Nneka Kunle-Ope
Isiyaku Ahmadu
Joshua Gowon
David B. Meshak

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1855903

594 views

Original Research

Published on 30 Jun 2026

The AcasR-FadD9 regulatory axis modulates iron homeostasis and susceptibility to the anti-mycobacterial compound ACA

in Pathogen and Host Biology of Tuberculosis

Feng Huang
Zixin Wang
Dong Jiang
Shengyi Li
Zheng-Guo He
Hua Zhang

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1830528

422 views

Original Research

Published on 25 Jun 2026

Using interpretable decision trees to explore TB-HIV integration under data constraints: a proof-of-concept analysis

in Epidemiology of Tuberculosis

Ntandazo Dlatu
Lindiwe Modest Faye
Mojisola Clara Hosu
Teke Apalata

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1853414

473 views

Original Research

Published on 18 Jun 2026

Identification of novel DNA gyrase B inhibitors in Mycobacterium species using integrated computational approaches

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Jagritee Yadav
Lalhmangaihzuali
Harish Shukla
Anshuman Chandra
Sudhir Kumar Singh
Meenakshi Singh

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1854329

919 views

Original Research

Published on 11 Jun 2026

Differential roles of resident lung macrophages during control of murine alveolar and airway Mycobacterium abscessus infection

in Non-Tuberculous Mycobacteria

Kelsey C. Haist
Jack H. Congel
Jodi M. Corley
Alma E. Ochoa
Jazalle McClendon
Patrick S. Hume
Jerry A. Nick
William J. Janssen
Kenneth C. Malcolm
Katherine B. Hisert

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1781507

821 views

Original Research

Published on 11 Jun 2026

Genomic characterization of drug-resistant Mycobacterium tuberculosis complex in western Kenya reveals predominance of isoniazid resistance and discordance with routine susceptibility testing

in Diagnosis of Tuberculosis

Susan Musau
Susan Odera
Victor Moses Musyoki
Eleanor I. Lamont
Noel Onyango
Bob Morrison
Wilfred Murithi
Steve Wandiga
Videlis Nduba
David Sherman

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1855780

809 views

Original Research

Published on 05 Jun 2026

Sigma factor M induces an ESX-4-focused regulon in Mycobacterium abscessus

in Non-Tuberculous Mycobacteria

Jill G. Canestrari
Shawn Gianola
Keith M. Derbyshire
Todd A. Gray

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1797268

887 views

Original Research

Published on 29 May 2026

Non-tuberculous mycobacteria pulmonary disease in Texas: an analysis of 8 years of hospital discharge data

in Non-Tuberculous Mycobacteria

Alex Baham
Jotam G. Pasipanodya
Devanshi Mehta
Susan McBride
Shashikant Srivastava

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1740382

1,037 views

Review

Published on 26 May 2026

Research overview—2025: integrating scientific progress to accelerate global tuberculosis elimination

in Epidemiology of Tuberculosis

Patrick K. Moonan
Timothy H. Holtz

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1805962

1,916 views

Perspective

Published on 23 Apr 2026

Readiness assessment as a strategy, not an afterthought: leveraging implementation science to integrate tuberculosis comorbidity care in Pakistan's health system

in Epidemiology of Tuberculosis

Saima Aleem
Zohaib Khan
Bilal Ahmad Khan
Zala
Saima Afaq

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1809118

1,250 views

Original Research

Published on 17 Apr 2026

Evaluation of the performance of promising host transcriptional biosignatures in predicting TB progression during a 1-year prospective cohort study in Indian household contacts

in Diagnosis of Tuberculosis

Synne Jenum
Steffen Hadasch
Dhanasekaran Sivakumaran
Christina Skår Saghaug
Jonas Høgberg
Kasama Chusang Larsen
Sumithra Selvan
Helene Larsen
Christian Ritz
Harleen M. S. Grewal

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1750007

1,039 views

Original Research

Published on 10 Apr 2026

Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity

in Immunological Basis of Tuberculosis

Vaishnavi Kaipilyawar
Samantha Leong
Arianne Lovey
Lorenzzo L. Stringari
Reynaldo Dietze
Jerrold J. Ellner
Rodrigo Ribeiro-Rodrigues
Padmini Salgame

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1783887

1,682 views

Editorial

Published on 01 Apr 2026

Editorial: Non-tuberculous mycobacteria and bronchiectasis

in Non-Tuberculous Mycobacteria

Octavio M. Rivero-Lezcano
Ramiro López-Medrano
Jaime Esteban

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1819209

1,164 views

Original Research

Published on 26 Mar 2026

Dose optimization of inhaled tigecycline in humans to overcome inherent adverse events and maximize bacterial clearance using a physiologically-based pharmacokinetic modeling approach

in Non-Tuberculous Mycobacteria

Hyunseo Park
Amarinder Singh
Ashish Srivastava
Bhargavi Thalluri
Christelle J. Mathieu
Paridhi Gupta
Camron M. Pearce
Malik Zohaib Ali
Ilham M. Alshiraihi
Sara E. Maloney Norcross

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1762713

1,769 views
1 citation

Review

Published on 25 Mar 2026

Advanced diagnostic methods for nontuberculous mycobacterial infections

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Sneha Singh
Amresh Kumar Singh
Sushil Kumar
Nandini Singh
Ashwini Kumar Mishra
Aroop Mohanty

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1760581

4,755 views
1 citation

Original Research

Published on 16 Feb 2026

Evaluation of host-immune biomarker signatures as multiplex qPCR diagnostic assays: a pilot study toward meeting WHO target product profiles for TB diagnosis in India

in Diagnosis of Tuberculosis

Harriet N. Garlant
Kalaiarasan Ellappan
Noyal Mariya Joseph
Carrie Turner
Vishnukanth Govindaraj
Saka Vinod Kumar
Sanjeev Kumar
Seshadri Vasan
Karen E. Kempsell

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1678039

1,954 views

Study Protocol

Published on 13 Feb 2026

An integrated psycho-social intervention to improve self-efficacy toward TB treatment uptake and infection prevention among patients and family caregivers: a multicentric implementation research study protocol

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Karikalan Nagaraj
Bella Devaleenal Daniel
Chandra Suresh
Dhanalakshmi Angamuthu
Shobana Palanisamy
Muniyandi Malaisamy

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1713844

1,282 views

Original Research

Published on 12 Feb 2026

Acceptability and feasibility of oral swabs for tuberculosis diagnosis in young children: a qualitative study from Uganda and Peru

in Diagnosis of Tuberculosis

Francesca W. Basile
Rodrigo Calderón-Flores
Franziska Held
Luisa Pollmeier
Emmanuel Nasinghe
Godfrey Bagenda
Lazaaro Mujumbusi
Rose Namaganda
Angel Kanyange
Prossy Mbekeeka

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1726647

1,511 views
1 citation

Original Research

Published on 27 Jan 2026

The “yeast-drop” treatment protocol in the Drosophila model for rapid and cost-effective TB drug testing

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Maria Vidal
Esther Fuentes
Nerea Escobar
Marta Arch
Pere-Joan Cardona

Frontiers in Tuberculosis

doi 10.3389/ftubr.2026.1746664

1,319 views

Original Research

Published on 13 Jan 2026

Evaluation of a short, all oral treatment regimen including bedaquiline, delamanid, linezolid, clofazimine, and pyrazinamide named “Regimen C” for pre-XDR tuberculosis in Niger

in Therapeutic Advances in Tuberculosis and Non-Tuberculous Mycobacterial Disease

Soumana Boubacar Soumana
Abdourahamane Yacouba
Cheikh Aboubacar Abdoul Lawi
Ibrahim Oumar
Bassirou Souleymane
Alphazazi Soumana
Tapha Ounoussa
Mahamadou Doutchi
Mamane Daou
Souleymane Brah

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1718997

1,470 views

Review

Published on 12 Jan 2026

Bidirectional pathogenesis between non-tuberculous mycobacteria and bronchiectasis: clinical insights, diagnostic challenges and future directions—Perspectives from South Asia

in Non-Tuberculous Mycobacteria

Amresh Kumar Singh
Sneha Singh
Nandini Singh
Priyanka Gaur
Ashwini Kumar Mishra
Raj Kishore Singh
Sushil Kumar

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1735568

2,871 views

74 articles

articles

Secreted proteins of Mycobacterium tuberculosis as therapeutic targets for drug discovery

Adjunctive antimycobacterial and immunomodulatory effects of Allium cepa (pink variety) in a rabbit model of latent-like mycobacterial infection

A Mycobacterium tuberculosis rare variable antigen vaccine reduces lung pathology in hypersusceptible SP140−/− mice

Implementation of sequencing-based surveillance for drug-resistant tuberculosis in Nigeria

The AcasR-FadD9 regulatory axis modulates iron homeostasis and susceptibility to the anti-mycobacterial compound ACA

Using interpretable decision trees to explore TB-HIV integration under data constraints: a proof-of-concept analysis

Identification of novel DNA gyrase B inhibitors in Mycobacterium species using integrated computational approaches

Differential roles of resident lung macrophages during control of murine alveolar and airway Mycobacterium abscessus infection

Genomic characterization of drug-resistant Mycobacterium tuberculosis complex in western Kenya reveals predominance of isoniazid resistance and discordance with routine susceptibility testing

Sigma factor M induces an ESX-4-focused regulon in Mycobacterium abscessus

Non-tuberculous mycobacteria pulmonary disease in Texas: an analysis of 8 years of hospital discharge data

Research overview—2025: integrating scientific progress to accelerate global tuberculosis elimination

Readiness assessment as a strategy, not an afterthought: leveraging implementation science to integrate tuberculosis comorbidity care in Pakistan's health system

Evaluation of the performance of promising host transcriptional biosignatures in predicting TB progression during a 1-year prospective cohort study in Indian household contacts

Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity

Editorial: Non-tuberculous mycobacteria and bronchiectasis

Dose optimization of inhaled tigecycline in humans to overcome inherent adverse events and maximize bacterial clearance using a physiologically-based pharmacokinetic modeling approach

Advanced diagnostic methods for nontuberculous mycobacterial infections

Evaluation of host-immune biomarker signatures as multiplex qPCR diagnostic assays: a pilot study toward meeting WHO target product profiles for TB diagnosis in India

An integrated psycho-social intervention to improve self-efficacy toward TB treatment uptake and infection prevention among patients and family caregivers: a multicentric implementation research study protocol

Acceptability and feasibility of oral swabs for tuberculosis diagnosis in young children: a qualitative study from Uganda and Peru

The “yeast-drop” treatment protocol in the Drosophila model for rapid and cost-effective TB drug testing

Evaluation of a short, all oral treatment regimen including bedaquiline, delamanid, linezolid, clofazimine, and pyrazinamide named “Regimen C” for pre-XDR tuberculosis in Niger

Bidirectional pathogenesis between non-tuberculous mycobacteria and bronchiectasis: clinical insights, diagnostic challenges and future directions—Perspectives from South Asia