ORIGINAL RESEARCH article
Front. Vet. Sci.
Sec. Parasitology
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1558328
The complete mitochondrial genomes of Macrostylophora euteles and Citellophilus tesquorum sungaris and the phylogenetics of known Siphonaptera mitogenomes
Provisionally accepted
Mingna Duan1
Yafang Liu1Jun Wu2Shuang Liu1
Shaobo Tang1Dandan Jiang3Quanfu Zhang4*Wei Gu5,6*
Xing Yang1*- 1Integrated Laboratory of Pathogenic Biology, College of Preclinical Medicine, Dali University, Dali, China
- 2Dali Bai Autonomous Prefecture People's Hospital Ophthalmology No.35 Renmin South Road, Xiaguan Town, Dali, Yunnan, China, Dali, China
- 3School of Public Health, Dali University, Dali, China
- 4Department of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan Province, China
- 5Department of Infection, The First Affiliated Hospital of Dali University, Dali, China
- 6the Key Laboratory of Infectious Diseases of Yunnan Provincial Education Department, Dali, China
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Fleas can serve as hosts to a diverse array of pathogens, which present significant medical and veterinary concerns for human and livestock health. In this study, we sequenced Macrostylophora euteles specimens collected from the Yunnan plague focus and Citellophilus tesquorum sungaris specimens from Jilin plague focus. The resulting sequences were compared with those of 24 flea species obtained from the NCBI database. All fleas analyzed contained a total of 37 genes. Gene sequences exhibited remarkable stability, with no evidence of gene rearrangement. Additionally, the base composition demonstrated a pronounced AT bias. Results from both methodologies and across the two datasets consistently indicated strong monophyly for the superfamilies Ceratophylloidea and Pulicoidea, as well as for the family Pulicidae. In contrast, the superfamily Hystrichopsylloidea, along with the families Ceratophyllidae, Leptopsyllidae and Ctenophthalmidae, were identified as paraphyletic. This research provides valuable molecular data to support taxonomic and phylogenetic studies of fleas.
Keywords: fleas, Macrostylophora euteles, Citellophilus tesquorum sungaris, 2 Mitochondrial genome, gene structure, phylogenetic
Received: 10 Jan 2025; Accepted: 14 Apr 2025.
Copyright: © 2025 Duan, Liu, Wu, Liu, Tang, Jiang, Zhang, Gu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Quanfu Zhang, Department of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan Province, China
Wei Gu, Department of Infection, The First Affiliated Hospital of Dali University, Dali, China
Xing Yang, Integrated Laboratory of Pathogenic Biology, College of Preclinical Medicine, Dali University, Dali, China
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