ORIGINAL RESEARCH article
Front. Vet. Sci.
Sec. Veterinary Epidemiology and Economics
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1582461
This article is part of the Research TopicAntimicrobial Resistance in Veterinary Medicine: Epidemiology, Economic Impact, and Mitigation StrategiesView all 6 articles
Prevalence and antimicrobial resistance of Streptococcus suis isolated from local pig breeds in Jiangxi Province, China
Provisionally accepted
Mei-Fang Tan1
Chen-Long Liu1Quan-Yong Zhou1Jia-Zhen Wei2Jia-Wei Hong2Ming-Chun Wan1Feng-Lin Zhang1
Huayuan Ji1*- 1Institute of Animal Husbandry and Veterinary Medicine, Jiangxi Academy of Agricultural Sciences, Nanchang, China
- 2Department of Animal Science, Jiangxi Biological Vocational College, Nanchang, Jiangxi Province, China
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Introduction: Jiangxi Province possesses abundant genetic resources of local pig breeds, whose effective conservation is essential for maintaining biodiversity and sustainable utilization. Streptococcus suis is an important zoonotic pathogen that continuously threatens swine production systems and public health globally. This study aimed to investigate the epidemiological characteristics of S. suis among local pig breeds in Jiangxi Province.Methods: An investigation was conducted on the prevalence and antimicrobial resistance profiles of S. suis in six local pig breeds from Jiangxi Province, including Gandong Black pig, Hang pig, Ganxi Two-end-black pig, Dongxiang Spotted pig, Yushan Black pig, and Binhu Black pig.Results: A total of 340 porcine nasal swabs were collected from six local pig breeds. 208 S. suis strains were isolated from 187 samples, with an overall isolation rate of 55.0%. The positive isolation rates of the six local breeds were 58.0%, 80.0%, 71.7%, 51.7%, 13.3%, and 60.0%, respectively. Antimicrobial susceptibility testing revealed that >98% of isolates were susceptible to carbapenems (meropenem and imipenem), followed by doxycycline (71.6%), ceftiofur (65.9%), spectinomycin (64.4%), and amoxicillin (55.8%). High resistance rates were observed for tilmicosin (96.6%), sulfadiazine (92.8%), colistin (89.9%), apramycin (88.9%), chlortetracycline (87.5%), tiamulin (83.2%), and kanamycin (79.8%). 100% of isolates exhibited multidrug resistance, with significant variations in resistance patterns among breeds. Genotypic analysis identified ermB (macrolides), tetL (tetracyclines), and Sul2 (sulfonamides) as the predominant resistance determinants.. Discussion: Multidrug-resistant S. suis strains have become widespread among local pig breeds. This study could provide evidence-based guidance for developing effective prevention and control strategies against S. suis infections and protecting valuable genetic resources of indigenous pig breeds.
Keywords: Streptococcus suis, Prevalence, antimicrobial resistance, Local pig breed, Jiangxi Province
Received: 24 Feb 2025; Accepted: 22 Jul 2025.
Copyright: © 2025 Tan, Liu, Zhou, Wei, Hong, Wan, Zhang and Ji. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Huayuan Ji, Institute of Animal Husbandry and Veterinary Medicine, Jiangxi Academy of Agricultural Sciences, Nanchang, China
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