REVIEW article

Front. Vet. Sci.

Sec. Animal Nutrition and Metabolism

Volume 12 - 2025 | doi: 10.3389/fvets.2025.1594749

This article is part of the Research TopicSustainable Nutritional Strategies for Improving Health Status, Egg and Meat Quality in PoultryView all 6 articles

Integrating Metabolomics for Precision Nutrition in Poultry: Optimizing Growth, Feed Efficiency, and Health

Provisionally accepted
Dr. Mohamed E.  Abd El-HackDr. Mohamed E. Abd El-Hack1*Ahmed  A AllamAhmed A Allam2Ahmed  K. AldhalmiAhmed K. Aldhalmi3Mahmoud  KamalMahmoud Kamal4Muhammad  ArifMuhammad Arif5Abdullah  S AlawamAbdullah S Alawam2Hassan  A RudayniHassan A Rudayni2Ayman  El-Sayed TahaAyman El-Sayed Taha6Ayman  A SwelumAyman A Swelum7Ahmed  A ElolimyAhmed A Elolimy8Mahmoud  MadkourMahmoud Madkour9Elwy  A AshourElwy A Ashour1
  • 1Zagazig University, Zagazig, Egypt
  • 2Imam Muhammad ibn Saud Islamic University, Riyadh, Saudi Arabia
  • 3College of Dentistry, Al-Mustaqbal University, Babylon, Iraq
  • 4Nanjing University, Nanjing, Jiangsu Province, China
  • 5University of Sargodha, Sargodha, Punjab, Pakistan
  • 6Alexandria University, Alexandria, Alexandria, Egypt
  • 7King Saud University, Riyadh, Riyadh, Saudi Arabia
  • 8United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates
  • 9National Research Centre (Egypt), Cairo, Cairo, Egypt

The final, formatted version of the article will be published soon.

Nutrition is an important factor in poultry production. This review highlights how precision nutrition improves poultry performance through metabolomics, which is a multidisciplinary approach that integrates traditional nutrition with other fields, including biology, immunology, molecular biology, genetics, computer sciences, chemistry, biochemistry, mathematics, engineering, and technology sciences. For measuring the results of the body's biochemical activities and figuring out Living systems' dynamic, multi-parametric metabolic response to pathological stimuli, metabolomics can be a very useful instrument. Numerous metabolomics techniques exist, including emerging capillary electrophoresis (CE), gas chromatography mass spectrometry (GC-MS), nuclear magnetic resonance spectroscopy (NMR), liquid chromatography mass spectrometry (LC-MS), inductively coupled plasma mass spectrometry (ICP-MS), and some targeted HPLC-based assays. Metabolomics can help in understanding the metabolism of diets (protein, carbohydrate, and fat) and the pathways of precise nutrition. Metabolomics can revolutionize poultry nutrition strategies, optimizing health, growth performance, and metabolic efficiency by decoding biochemical interactions between diet, metabolism, and physiology. This review aims to highlight methodologies for integrating metabolomic data into precision feeding systems, ultimately enhancing sustainability, reducing production costs, and improving poultry welfare.

Keywords: Metabolomics, Growth, feed efficiency, Poultry, Precision nutrition

Received: 16 Mar 2025; Accepted: 01 May 2025.

Copyright: © 2025 Abd El-Hack, Allam, Aldhalmi, Kamal, Arif, Alawam, Rudayni, Taha, Swelum, Elolimy, Madkour and Ashour. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Mohamed E. Abd El-Hack, Zagazig University, Zagazig, Egypt

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