ORIGINAL RESEARCH article
Front. Vet. Sci.
Sec. Veterinary Epidemiology and Economics
This article is part of the Research TopicAdvancements in the Understanding, Diagnosis, and Control of Viral Diseases of Cattle, Goats, and SheepView all 9 articles
Identification of a Novel Ungulate Copiparvovirus 10 in Sheep of Hami, East Xinjiang, China
Provisionally accepted
Jinxin Xie1,2,3*
Juanjuan Pan1Haichun Jiang4Shengjin Luo5Lei Zhang6Guiling Wu6Wen Li5Shudong Cai5Yang Mei7Xintong Chen1Baoyu Chen1,8Weiwei Zhang9
Panpan Tong1- 1Xinjiang Agricultural University, Ürümqi, China
- 2Xinjiang Key Laboratory of New Drug Research and Development for Herbivores, Urumqi, China
- 3Key laboratory for animal disease detection,College of Animal Sciences, Yili Vocational and Technical College, Yili, China
- 4Dahe Town Agricultural (Livestock) Development Service Center, Barkun County, Hami, China
- 5Animal Husbandry Station of Hami City, Hami, China
- 6Aksu Regional Animal Disease Control and Diagnostic Center, Aksu, China
- 7Yiwu County Livestock Work Service Center, Hami, China
- 8Guangzhou Kexiang Biological Technology Co., Ltd, Guangzhou, China
- 9Tacheng Vocational and Technical College, Tacheng, China
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Parvovirinae viruses are a subfamily of the Parvoviridae family that can infect various vertebrate hosts and cause infections ranging from asymptomatic to severe disease. This study performed a metagenomic assessment of the sheep sera virome to evaluate emerging and exotic viruses in border zones, and identified a novel copiparvovirus. The DNA of Ovine copiparvovirus (OVPV) was only observed in the serum of sheep in Dahe Town of Hami City. Furthermore, the region-dependent prevalence was 10.4% (96/807) from 2022 to 2024. The OVPV genome was 5219 nucleotides (nt) long and shared 99.3% nt identity with two bovine parvovirus 2 SXO335parvoV2 and SXO338parvoV (GenBank accession numbers: MZ244302 and MZ244302), reported in the ticks collected from China. Comparison of NS1 protein showed that two OVPVs obtained in this study had 99.8‒99.9% amino acid homology with the tick-derived bovine parvoviruses, which had not been classified within the genus Copiparvovirus and then provisionally designated "Ungulate copiparvovirus 10", because they are far distant from other 10 species in Copiparvovirus genus with 48.5‒72.8% homology identified. Phylogenetic analysis further confirmed the classification of the OVPVs as a new species in the genus Copiparvovirus.
Keywords: China, East Xinjiang, novel, Sheep, Ungulate copiparvovirus 10
Received: 03 Aug 2025; Accepted: 05 Jan 2026.
Copyright: © 2026 Xie, Pan, Jiang, Luo, Zhang, Wu, Li, Cai, Mei, Chen, Chen, Zhang and Tong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jinxin Xie
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