Research Topic

Neuropeptide Circuits for Social Behavior

About this Research Topic

Neuropeptides and their cognate receptors have long been implicated in the modulation of social behavior across diverse taxa. However, a major difficulty in defining the mechanisms by which neuropeptides influence behavior is that they are expressed in many brain regions and often influence brain, behavior, and physiology in different ways, depending on the specific circuits in which they are expressed. Recent work on specific neuropeptide circuits has substantially increased our understanding of the diversity of neuropeptide action on social behavior. This Research Topic will provide some prominent examples of these circuits.

The goal is to present a spectrum of approaches to reveal the mechanisms via which neuropeptides act on the neural substrate of social behavior. This focus on specific circuits may better inform both basic and translational research on mechanisms by which social behavior is generated and how social deficits in psychiatric disorders are caused.

While most of the work on neuropeptides and social behavior has focused on oxytocin and, to a lesser degree, vasopressin, evaluating the operating rules of how neuropeptides control social behavior requires a broader consideration of other neuropeptide circuits. Consequently, this Research Topic will encompass a diverse set of neuropeptides that influence social behavior through identified neural networks.

We welcome reviews, mini reviews, original research, and perspective articles.


Keywords: Neuropeptides, social circuits, neuropeptide systems


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Neuropeptides and their cognate receptors have long been implicated in the modulation of social behavior across diverse taxa. However, a major difficulty in defining the mechanisms by which neuropeptides influence behavior is that they are expressed in many brain regions and often influence brain, behavior, and physiology in different ways, depending on the specific circuits in which they are expressed. Recent work on specific neuropeptide circuits has substantially increased our understanding of the diversity of neuropeptide action on social behavior. This Research Topic will provide some prominent examples of these circuits.

The goal is to present a spectrum of approaches to reveal the mechanisms via which neuropeptides act on the neural substrate of social behavior. This focus on specific circuits may better inform both basic and translational research on mechanisms by which social behavior is generated and how social deficits in psychiatric disorders are caused.

While most of the work on neuropeptides and social behavior has focused on oxytocin and, to a lesser degree, vasopressin, evaluating the operating rules of how neuropeptides control social behavior requires a broader consideration of other neuropeptide circuits. Consequently, this Research Topic will encompass a diverse set of neuropeptides that influence social behavior through identified neural networks.

We welcome reviews, mini reviews, original research, and perspective articles.


Keywords: Neuropeptides, social circuits, neuropeptide systems


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

12 January 2022 Abstract
19 April 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

12 January 2022 Abstract
19 April 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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