About this Research Topic
Neuropeptides and their cognate receptors have long been implicated in the modulation of social behavior across diverse taxa. However, a major difficulty in defining the mechanisms by which neuropeptides influence behavior is that they are expressed in many brain regions and often influence brain, behavior, and physiology in different ways, depending on the specific circuits in which they are expressed. Recent work on specific neuropeptide circuits has substantially increased our understanding of the diversity of neuropeptide action on social behavior. This Research Topic will provide some prominent examples of these circuits.
The goal is to present a spectrum of approaches to reveal the mechanisms via which neuropeptides act on the neural substrate of social behavior. This focus on specific circuits may better inform both basic and translational research on mechanisms by which social behavior is generated and how social deficits in psychiatric disorders are caused.
While most of the work on neuropeptides and social behavior has focused on oxytocin and, to a lesser degree, vasopressin, evaluating the operating rules of how neuropeptides control social behavior requires a broader consideration of other neuropeptide circuits. Consequently, this Research Topic will encompass a diverse set of neuropeptides that influence social behavior through identified neural networks.
We welcome reviews, mini reviews, original research, and perspective articles.
Keywords: Neuropeptides, social circuits, neuropeptide systems
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