Research Topic

Burkholderia cepacia complex: an embarrassment of niches

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Burkholderia cepacia complex (Bcc) is a group of at least 17 distinct but phenotypically similar species that are found in diverse environments. Some can cause diseases in plants, while others can promote plant growth. Bcc have been found that can degrade man-made or natural pollutants. Importantly ...

Burkholderia cepacia complex (Bcc) is a group of at least 17 distinct but phenotypically similar species that are found in diverse environments. Some can cause diseases in plants, while others can promote plant growth. Bcc have been found that can degrade man-made or natural pollutants. Importantly members of this group are naturally antibiotic resistant and can cause severe infections in immunocompromised individuals including cystic fibrosis and chronic granulomatous disease patients. This Research Topics issue will be devoted to the distinctive aspects of Bcc, in particular as they relate to niche adaptation and survival in the environment, epidemiological prominence and transmission, metabolic and virulence factor expression patterns, and host interactions and disease manifestations. Recent progress of Bcc will be summarized through studies at the metagenomic, taxonomic, and population level, optimization of the production of biologically useful enzymes and compounds, as well as specific mechanisms related to host immune evasion and the identification of potential targets for therapeutic intervention and vaccine development.

Abstract submission deadline: 1 July 2011
Full article submission deadline: 1 September 2011


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