Advancing Research, Clinical Recognition, and Targeted Therapies for WHIM Syndrome

2,714
Total downloads
10k
Total views and downloads

Articles

ORIGINAL RESEARCH

Published on 11 Nov 2024

CXCR4 antagonism ameliorates leukocyte abnormalities in a preclinical model of WHIM syndrome

Lilian Roland
Chi Huu Nguyen
Katarina Zmajkovicova
Mélanie Khamyath
Maria Kalogeraki
Bérénice Schell
Vanessa Gourhand
Vincent Rondeau
Zeina Abou Nader
5 more
Karl Balabanian

doi 10.3389/fimmu.2024.1468823

1,508 views
1 citation

ORIGINAL RESEARCH

Published on 07 Nov 2024

Heterogeneous phenotype of a Chinese Familial WHIM syndrome with CXCR4V340fs gain-of-function mutation

Yu Huang
Lu Li
Ran Chen
Lang Yu
Shunkai Zhao
Yanjun Jia
Ying Dou
Zhiyong Zhang
Yunfei An
2 more
Lina Zhou

doi 10.3389/fimmu.2024.1460990

1,074 views

MINI REVIEW

Published on 08 Jul 2024

Expanding CXCR4 variant landscape in WHIM syndrome: integrating clinical and functional data for variant interpretation

Katarina Zmajkovicova
Keith Nykamp
Grace Blair
Melis Yilmaz
Jolan E. Walter

doi 10.3389/fimmu.2024.1411141

2,482 views
2 citations

REVIEW

Published on 05 Jul 2024

The complex nature of CXCR4 mutations in WHIM syndrome

José Miguel Rodríguez-Frade
Luis Ignacio González-Granado
César A. Santiago
Mario Mellado

doi 10.3389/fimmu.2024.1406532

2,635 views
2 citations

Share on

Frontiers in Immunology

Frontiers in Immunology

Primary Immunodeficiencies

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

Impact

10kTopic views
6,796Article views
2,714Article downloads