About this Research Topic
However, there are still many challenges to be overcome, such as optimizing the production and application of cellulosomes at industrial scale, and developing systems to better control the composition of cellulosomes. Hence, the major goal of this Research Topic is to gather novel research in the isolation, identification of novel cellulosome producing bacterial or fungal species from various habitats, and the identification and characterization of novel cellulosomal enzymes to achieve efficient biomass degradation.
This Research Topic also focuses on the modification of native cellulosomes to create novel designer cellulosomes using genetic engineering tools to enhance enzyme proximity and synergism. But also, the engineering of cellulosomal systems into industrial ethanologenic organisms for use in consolidated bioprocessing approaches.
Hence, this Research Topic aims to gather Original Research, Review, Mini Reviews, and Perspectives relating to but not limited to the following themes:
• Isolation and identification of novel cellulosomes.
• Isolation and characterization of novel cellulosomal enzymes.
• Demonstration of novel cellulosomal complex formation (new or modified cohesin-dockerin interaction).
• Structural studies of cellulosomal complexes formation using x-ray crystallography or cryo-electron microscopy.
• Incorporation of novel enzymes into cellulosomes.
• Development of the ‘designer cellulosomes’ and their application in bioenergy production.
• Engineering of cellulosomal genes into an industrial host to enable the development of new CBP hosts.
Keywords: cellulosome, Protein Complex, Biofuel Production, Enzyme Engineering, Biodegradation, Consolidated Bioprocessing, Sustainable Energy, Sustainability, Biofuel
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.