Male (In)Fertility in Mammals: Latest Insights, Assessment and Biotechnologies for a Better Understanding

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Background

Recent years have seen substantial advances in knowledge of sperm biology and biotechnologies and knowledge of these areas is more advanced in some mammalian species than others. There is therefore a wide variability in fertility in some animal species and humans, in particular those not selected for their reproductive capacity and a lack of basic understanding as to the causes of infertility and intolerance of assisted reproductive technologies. To fully understand the mechanisms behind individual variability and molecular causes of (in)fertility a deeper understanding of sperm biology and metabolism is necessary.

This research topic aims to collate and gather high impact research from a range of complementary disciplines and research approaches to male (in)fertility in both animals and humans, bringing together the latest knowledge regarding the mechanisms behind (in)fertility, identification of new biomarkers to recognize fertility variations, especially those which are clinically applicable, aspects of seminal plasma linked to (in)fertility, the latest biotechnologies in the field and analytic techniques.

We invite researchers, clinicians, and experts from various fields of male (in)fertility and reproductive science to contribute their high-quality original research articles. We welcome contributions covering a range of topics including, but not limited to, the following:

- New biomarkers of male (in)fertility
- Cellular mechanisms behind spermatozoa function
- New biotechnologies applied to spermatozoa to improve fertility outcomes
- The effect of disease on male (in)fertility
- New insights into the role of seminal plasma
- Comparative studies of (in)fertility between species
- Analytic techniques for spermatozoa

Keywords: reproduction, infertility, spermatozoa, seminal plasma, biomarkers, male mammalian reproduction

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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