Optimizing GLP-1 Receptor Agonist Use: Mechanisms, Clinical Applications, and Safety Profiles

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ORIGINAL RESEARCH

Accepted on 27 Aug 2025

Digital multicriteria evaluation of negotiated medicines using Chinese mini-HTA: Application of structured methodologies in assessing once-weekly GLP-1 RAs for improved clinical decision-making

Xiao Li
Zhihong Qiu
Chaojun Xue
Zhanjun Dong

doi 10.3389/fphar.2025.1588056

165 views

SYSTEMATIC REVIEW

Published on 26 Aug 2025

Effect of semaglutide on arrhythmic, major cardiovascular, and microvascular outcomes in patients with type 2 diabetes: a systematic review and meta-analysis

Rui Wu
Bo Xing
Yuting Huang
Zijun Zhou
Boxuan Sun
Liming Yu
Huishan Wang

doi 10.3389/fendo.2025.1554795

422 views

SYSTEMATIC REVIEW

Accepted on 21 Aug 2025

Comparative Gastrointestinal Adverse Effects of GLP-1 Receptor Agonists and Multi-Target Analogs in Type 2 Diabetes: A Bayesian Network Meta-Analysis in Type 2 Diabetes: A Bayesian Network Meta-Analysis

Xingmiao Xie
Shuiyuan Yang
Shuzhen Deng
Yuying Liu
Zhibin Xu
Binghong He

doi 10.3389/fphar.2025.1613610

194 views

REVIEW

Published on 24 Jul 2025

Unlocking the potential of GLP-1 receptor agonists in ocular therapeutics: from molecular pathways to clinical impact

Zhixuan Xie
Zuyi Yang
Dianzhe Tian
Youxin Chen

doi 10.3389/fphar.2025.1618079

1,288 views

MINI REVIEW

Published on 30 May 2025

GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

Shujun Li
Nanqu Huang
Mei Wang
Wendi Huang
Yong Luo
Juan Huang

doi 10.3389/fphar.2025.1610512

1,635 views
1 citation

ORIGINAL RESEARCH

Published on 22 May 2025

Glucagon-like peptide-1, fibroblast growth factor 21, and other endocrine responses to alcohol ingestion in women before and after metabolic surgery

Mariel Molina-Castro
Blair Rowitz
Marta Yanina Pepino

doi 10.3389/fphar.2025.1575156

1,488 views

ORIGINAL RESEARCH

Published on 04 Sep 2024

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection (ALND)

Stav Brown
Audree B. Tadros
Giacomo Montagna
Tajah Bell
Fionnuala Crowley
Emily J. Gallagher
Joseph H. Dayan

doi 10.3389/fphar.2024.1457363

6,387 views
2 citations

CLINICAL TRIAL

Published on 22 Aug 2024

Pharmacokinetics and safety profiles of beinaglutide injection, a recombinant human GLP-1, in adults with overweight/obesity: results from a phase I clinical trial

Pingping Lin
Chengqian Li
Yanping Liu
Feifei Sun
Tsung-Han Hsieh
Lin Zhang
Yaping Ma
Xiaomeng Gao
Qing Yu
Yu Cao

doi 10.3389/fphar.2024.1433587

2,110 views
3 citations

ORIGINAL RESEARCH

Published on 16 Aug 2024

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius

Christian E. Edvardsson
Jesper Vestlund
Mia Ericson
Elisabet Jerlhag

doi 10.3389/fphar.2024.1439203

2,310 views
4 citations

ORIGINAL RESEARCH

Published on 08 Jul 2024

Pharmacovigilance study of GLP-1 receptor agonists for metabolic and nutritional adverse events

Long He
Qiuyu Li
Yongfeng Yang
Jiahao Li
Wei Luo
Yilan Huang
Xiaoyan Zhong

doi 10.3389/fphar.2024.1416985

6,637 views
13 citations

CASE REPORT

Published on 18 Apr 2024

GLP-1 receptor agonist as an effective treatment for breast cancer-related lymphedema: a case report

Fionnuala Crowley
Stav Brown
Emily J. Gallagher
Joseph H. Dayan

doi 10.3389/fonc.2024.1392375

11,866 views
5 citations

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Translational Pharmacology

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Articles

Digital multicriteria evaluation of negotiated medicines using Chinese mini-HTA: Application of structured methodologies in assessing once-weekly GLP-1 RAs for improved clinical decision-making

Effect of semaglutide on arrhythmic, major cardiovascular, and microvascular outcomes in patients with type 2 diabetes: a systematic review and meta-analysis

Comparative Gastrointestinal Adverse Effects of GLP-1 Receptor Agonists and Multi-Target Analogs in Type 2 Diabetes: A Bayesian Network Meta-Analysis in Type 2 Diabetes: A Bayesian Network Meta-Analysis

Unlocking the potential of GLP-1 receptor agonists in ocular therapeutics: from molecular pathways to clinical impact

GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

Glucagon-like peptide-1, fibroblast growth factor 21, and other endocrine responses to alcohol ingestion in women before and after metabolic surgery

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection (ALND)

Pharmacokinetics and safety profiles of beinaglutide injection, a recombinant human GLP-1, in adults with overweight/obesity: results from a phase I clinical trial

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius

Pharmacovigilance study of GLP-1 receptor agonists for metabolic and nutritional adverse events

GLP-1 receptor agonist as an effective treatment for breast cancer-related lymphedema: a case report

Frontiers in Pharmacology

Translational Pharmacology