ORIGINAL RESEARCH
Published on 12 Jan 2026
Scalable CAR-T production in a 2-litre perfusion stirred-tank bioreactor with automated harvesting and scale-down model characterisation
doi 10.3389/fbioe.2025.1694134
- 1,764 views
- Frontiers in Bioengineering and Biotechnology
- Cell and Gene Therapy
- Research Topics
- Design Strategies and Equipment Requirements for Efficient Process Development and Robust Manufacturing of Cell Therapies
Design Strategies and Equipment Requirements for Efficient Process Development and Robust Manufacturing of Cell Therapies
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Articles
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- 1 citation
PERSPECTIVE
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- 1 citation
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doi 10.3389/fbioe.2025.1608194
- 2,726 views
METHODS
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Implementation of a quality management system for decentralized manufacturing of cell and gene therapy products - technical and regulatory considerations
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- 2,263 views
- 1 citation
ORIGINAL RESEARCH
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Enhanced cancer cell sorting using lab-on-a-disk pattern design with magnetic and centrifugal forces
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- 1,648 views
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Automated, aseptic sampling with small-volume capacity from microbioreactors for cell therapy process analysis
doi 10.3389/fbioe.2025.1612648
- 2,916 views
ORIGINAL RESEARCH
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Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes: a proof of concept
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- 2,543 views
ORIGINAL RESEARCH
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Closed-system manufacturing of therapeutic NK cells using automated cell enrichment and concentration processes enables scalable, robust and cost-effective solutions
doi 10.3389/fbioe.2025.1586912
- 3,680 views
- 2 citations
ORIGINAL RESEARCH
Published on 02 Jun 2025
Optimising and adapting perfusion feeds in serum-free medium to intensify CAR-T cell expansion in stirred-tank bioreactors
doi 10.3389/fbioe.2025.1593895
- 4,256 views
- 3 citations
