Gut microbiome and immune system

While it is known that certain microorganisms are implicated in tumor development, the underlying mechanisms still remain inadequately characterized. In addition to this, there is growing evidence that the gut microbiome significantly influences the efficacy of anti-cancer therapies. This field of study, known as pharmacomicrobiomics, examines the interactions between drugs and the gut microbiome. Importantly, there exists a bidirectional relationship between the gut microbiome and the immune system. Microbes residing in the human body have the ability to affect the immune system both locally and systemically, highlighting their critical role in health and disease.

The main goal of this Research Topic is to provide a fresh perspective on the intricate interactions between the gut microbiome and the immune system, particularly in the context of tumors. This topic aims to explore new insights and advancements that can contribute to a deeper understanding of these complex relationships. The specific areas covered within this scope include:

- Immunonutrition and its relationship with the gut microbiome
-The molecular basis of tumor development in relation to immune aspects and the gut microbiome
-The impact of various microbes on the immune system's functioning
-The interactions between the tumor microenvironment and microorganisms

Through this exploration, the research seeks to uncover novel therapeutic targets and strategies that could lead to more effective cancer treatments by leveraging the interplay between microbes and the immune system. By examining these areas, we aim to advance the field and contribute to improved patient outcomes in cancer therapy.

The topic editors declare no conflict of interests

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Case Report
• Classification
• Clinical Trial
• Editorial
• FAIR² Data
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• General Commentary
• Hypothesis and Theory
• Methods
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Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Case Report
• Classification
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Keywords: gut microbiome, immune system, oncology, gastrointestinal cancers, tumor

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.