Towards the Rapid and Systematic Assessment of Vaccine Technologies

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ORIGINAL RESEARCH

Published on 05 Jan 2026

An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models

Zachary R. Stromberg
Elvia E. Silva
Sara C. Johnston
Dylan M. Johnson
Dominique Hall
Emmanuel F. Adjei
John A. Altin
Abisola Abisoye-Ogunniyan
Travis Gollott
17 more
Oscar A. Negrete

doi 10.3389/fimmu.2025.1682418

501 views

REVIEW

Published on 19 Nov 2025

Yeast vaccine production platform for human and animal infectious diseases

Abel Ramos-Vega
Elizabeth Monreal-Escalante
Bernardo Bañuelos-Hernández
Miriam Angulo
Edgar Trujillo
Carlos Angulo

doi 10.3389/fimmu.2025.1697177

2,106 views

ORIGINAL RESEARCH

Published on 19 Sep 2025

Heterologous prime-pull mucosal vaccination with an adjuvanted RBD vaccine elicits robust IgA production and protects against SARS-CoV-2

Allyson H. Hirsch
Calder R. Ellsworth
William A. Lewis
Ryan Craig
Amy E. Meyer
Jonatan Maldonado
Frania Ramirez Lopez
Syamala Rani Thimmiraju
James B. McLachlan
6 more
Lisa A. Morici

doi 10.3389/fimmu.2025.1673460

4,007 views

ORIGINAL RESEARCH

Published on 03 Jul 2025

PepSeq as a highly multiplexed platform for melioidosis antigen discovery and vaccine development

Evan A. Elko
Charles H. D. Williamson
Heather R. Green
Marcellene A. Gates-Hollingsworth
Georgia A. Nelson
Sujata G. Pandit
Heather L. Mead
Christopher Allender
Celeste Woerle
6 more
Jason T. Ladner

doi 10.3389/fimmu.2025.1605758

2,063 views
1 citation

ORIGINAL RESEARCH

Published on 26 Jun 2025

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

Sergei S. Biryukov
Amy Rasley
Michael L. Davies
Christopher P. Klimko
Jennifer L. Dankmeyer
Melissa Hunter
Nathaniel O. Rill
Jennifer L. Shoe
Jeremy Miller
14 more
Christopher K. Cote

doi 10.3389/fimmu.2025.1603710

2,952 views

ORIGINAL RESEARCH

Published on 26 Jun 2025

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

Kristen M. Wilding
Carmen Molina-París
Jessica Z. Kubicek-Sutherland
Benjamin McMahon
Alan S. Perelson
Ruy M. Ribeiro

doi 10.3389/fimmu.2025.1596518

2,893 views

BRIEF RESEARCH REPORT

Published on 25 Jun 2025

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

Michael L. Davies
Sergei S. Biryukov
Christopher P. Klimko
Jennifer L. Dankmeyer
Nathaniel O. Rill
Melissa Hunter
Christopher T. Braun
Deven W. Patrick
Tyrique D. David
5 more
Christopher K. Cote

doi 10.3389/fimmu.2025.1612540

1,472 views

REVIEW

Published on 24 Jun 2025

Melioidosis vaccines: recent advances and future directions

Sineenart Sengyee
Sarah B. Weiby
Ivory T. Rok
Mary N. Burtnick
Paul J. Brett

doi 10.3389/fimmu.2025.1582113

2,704 views
2 citations

ORIGINAL RESEARCH

Published on 20 Jun 2025

Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei

Sergei S. Biryukov
Christopher K. Cote
Christopher P. Klimko
Jennifer L. Dankmeyer
Nathaniel O. Rill
Melissa Hunter
Michael L. Davies
Zander M. Hedrick
Jennifer L. Shoe
6 more
David DeShazer

doi 10.3389/fimmu.2025.1596265

1,834 views

REVIEW

Published on 10 Jun 2025

Nanoparticle approaches for manipulating cytokine delivery and neutralization

Rui Wang
Luke J. Kubiatowicz
Runhe Zhang
Lin Bao
Ronnie H. Fang
Liangfang Zhang

doi 10.3389/fimmu.2025.1592795

3,329 views
3 citations

REVIEW

Published on 21 May 2025

Methods integrating innate and adaptive immune responses in human in vitro immunization assays

Tetiana Y. Bowley
Kiersten D. Lenz
Apoorv Shanker
Jessica Z. Kubicek-Sutherland

doi 10.3389/fimmu.2025.1584852

3,211 views

SYSTEMATIC REVIEW

Published on 08 May 2025

Artificial intelligence in vaccine research and development: an umbrella review

Rabie Adel El Arab
May Alkhunaizi
Yousef N. Alhashem
Alissar Al Khatib
Munirah Bubsheet
Salwa Hassanein

doi 10.3389/fimmu.2025.1567116

16,481 views
26 citations

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Frontiers in Immunology

Vaccines and Molecular Therapeutics

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Articles

An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models

Yeast vaccine production platform for human and animal infectious diseases

Heterologous prime-pull mucosal vaccination with an adjuvanted RBD vaccine elicits robust IgA production and protects against SARS-CoV-2

PepSeq as a highly multiplexed platform for melioidosis antigen discovery and vaccine development

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

Melioidosis vaccines: recent advances and future directions

Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei

Nanoparticle approaches for manipulating cytokine delivery and neutralization

Methods integrating innate and adaptive immune responses in human in vitro immunization assays

Artificial intelligence in vaccine research and development: an umbrella review

Frontiers in Immunology

Vaccines and Molecular Therapeutics