Deciphering Host-Virus Interactions and Advancing Therapeutics for Chronic Viral Infection

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ORIGINAL RESEARCH

Published on 22 Sep 2025

HIV subtype-specific gp140-CD4 binding, Temsavir efficacy, and identification of novel adhesion inhibitors against Chinese HIV strains

Tianyang Liu
Xiaowen Li
Xiaolin Yang
Shengjie Zhang
Yao Wang
Siwei Zhang
Lin Cheng
Shanshan Tang
Fuxiang Wang
2 more
Lanlan Wei

doi 10.3389/fimmu.2025.1648546

1,065 views

SYSTEMATIC REVIEW

Published on 01 Sep 2025

Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review

Ása Didriksen Apol
Christina Sølund
Caroline Vinten
Alexander P. Underwood
Jens Bukh
Nina Weis

doi 10.3389/fimmu.2025.1546915

1,274 views

ORIGINAL RESEARCH

Published on 29 May 2025

A nomogram for predicting unfavorable outcomes of antituberculosis treatment among individuals with AIDS combined with pulmonary tuberculosis in China

Xiaoxu Han
Jin Sun
Yuan Gao
Hongxia Yan
Xiangchuan He
Yuanyuan Ma
Peng Xu
Ning Ding
Xin Zhang
3 more
Bin Su

doi 10.3389/fimmu.2025.1594107

1,475 views

ORIGINAL RESEARCH

Published on 09 May 2025

Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice

Yu-Syuan You
Wan-Ting Chang
Chia-Lang Hsu
Hui-Ying Wang
Yan-Fong Lu
InKyeom Kim
Shiang-Jong Tzeng

doi 10.3389/fimmu.2025.1548814

1,897 views

ORIGINAL RESEARCH

Published on 08 Apr 2025

Human papillomavirus E2 proteins suppress innate antiviral signaling pathways

Jin-Xin Li
Jing Zhang
Cheng-Hao Li
Qing Zhang
Beihua Kong
Pei-Hui Wang

doi 10.3389/fimmu.2025.1555629

2,260 views
2 citations

ORIGINAL RESEARCH

Published on 25 Mar 2025

AI discovery of TLR agonist-driven phenotypes reveals unique features of peripheral cells from healthy donors and ART-suppressed people living with HIV

Robert Were Omange
Samuel C. Kim
Nikita S. Kolhatkar
Tempest Plott
Will Van Trump
Kenneth Zhang
Hope O’Donnell
Daniel Chen
Ahmed Hosny
7 more
Jeffrey J. Wallin

doi 10.3389/fimmu.2025.1541152

2,620 views
2 citations

REVIEW

Published on 25 Feb 2025

HIV controllers: hope for a functional cure

Zhuoya Deng
Hongxia Yan
Olivier Lambotte
Christiane Moog
Bin Su

doi 10.3389/fimmu.2025.1540932

4,110 views
2 citations

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Frontiers in Immunology

Viral Immunology

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Articles

HIV subtype-specific gp140-CD4 binding, Temsavir efficacy, and identification of novel adhesion inhibitors against Chinese HIV strains

Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review

A nomogram for predicting unfavorable outcomes of antituberculosis treatment among individuals with AIDS combined with pulmonary tuberculosis in China

Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice

Human papillomavirus E2 proteins suppress innate antiviral signaling pathways

AI discovery of TLR agonist-driven phenotypes reveals unique features of peripheral cells from healthy donors and ART-suppressed people living with HIV

HIV controllers: hope for a functional cure

Frontiers in Immunology

Viral Immunology