About this Research Topic
In the last decades, a fast-evolving field around neuroinflammation has expanded considerably. Neuroinflammatory mechanisms involving immune molecules and cells play critical roles in normal brain functions and disease. A comprehensive understanding of key players and the cellular and molecular pathways involved in the induction of neuroinflammation is essential for developing effective therapeutic strategies to mitigate its long-term impact on the brain and peripheral tissues and providing new insights into fundamental mechanisms involved in normal brain development and function.
Despite extensive research that associates neuroinflammation as a critical player in the pathogenesis of several neurological pathologies, many questions remain unanswered regarding the mechanisms that regulate neuroimmune responses in disease and homeostasis maintenance. This research topic aims to consolidate articles describing current findings on potential triggers and cellular signaling pathways involved in neuroinflammation. Additionally, it seeks to provide new insights into novel molecular targets and therapeutic alternatives to prevent or improve the outcome of inflammatory, neurodegenerative, and neurological pathologies.
This research topic will include original research, reviews, clinical studies and short reports based on (but not restricted to) the following topics:
• Genetic and environmental triggers of neuroinflammation
• Molecular and cellular mechanisms underlying neuroinflammatory processes
• Novel therapeutic targets and strategies to modulate or mitigate neuroinflammation
• Impact of lifestyle factors on neuroinflammation and cognitive health
Despite extensive research that associates neuroinflammation as a critical player in the pathogenesis of several neurological pathologies, many questions remain unanswered regarding the mechanisms that regulate neuroimmune responses in disease and homeostasis maintenance. This research topic aims to consolidate articles describing current findings on potential triggers and cellular signaling pathways involved in neuroinflammation. Additionally, it seeks to provide new insights into novel molecular targets and therapeutic alternatives to prevent or improve the outcome of inflammatory, neurodegenerative, and neurological pathologies.
This research topic will include original research, reviews, clinical studies and short reports based on (but not restricted to) the following topics:
• Genetic and environmental triggers of neuroinflammation
• Molecular and cellular mechanisms underlying neuroinflammatory processes
• Novel therapeutic targets and strategies to modulate or mitigate neuroinflammation
• Impact of lifestyle factors on neuroinflammation and cognitive health
Keywords: Neuroinflammation, glial activation, neuroimmune crosstalk, neurodegenerative diseases, neurocognitive disorders
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
