New Frontiers in Heart Failure Therapy: Mechanisms, Efficacy, and Challenges

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ORIGINAL RESEARCH

Published on 22 Sep 2025

Evaluation of left ventricular systolic function in different subtypes of pediatric acute lymphoblastic leukemia: a case-control study based on two-dimensional speckle tracking

Yanfeng Yang
Chunyan Fu
Kun Shi
Yonghong Guo
Peng Shi
Hanmin Liu
Ling Gu
Ying Xiong

doi 10.3389/fphar.2025.1669049

1,247 views

SYSTEMATIC REVIEW

Published on 12 Sep 2025

A systematic review and meta-analysis on the efficacy and safety of finerenone in the progression of heart failure

Shengtian Peng
Peipei Li
Zhixi Yu
Beibei Du
Ping Yang

doi 10.3389/fphar.2025.1575307

1,038 views

ORIGINAL RESEARCH

Published on 12 Aug 2025

Effects of angiotensin receptor–neprilysin inhibition on myocardial energy metabolism and prognosis in patients with acute myocardial infarction complicated by heart failure

Caiming Cheng
Yu Nie
Di Chen
Yan Yang
Shunji Liang
Qin Yu

doi 10.3389/fcvm.2025.1550624

1,228 views

REVIEW

Published on 04 Aug 2025

Long-acting relaxin analogues: a novel tool in cardiology

Łukasz Wołowiec
Albert Jaśniak
Joanna Osiak-Gwiazdowska
Daria Czaplińska
Agata Szymczak
Julia Anna Pęcherz
Grzegorz Grześk

doi 10.3389/fphar.2025.1626469

1,047 views

BRIEF RESEARCH REPORT

Published on 31 Jul 2025

Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission

Małgorzata Małek-Elikowska
Andrzej Szyszka
Julita Fedorowicz
Rafał Dankowski
Cyntia Szymańska
Artur Baszko

doi 10.3389/fphar.2025.1643077

991 views

ORIGINAL RESEARCH

Published on 28 Jul 2025

Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis

Yilin Zhang
Jingjing Wei
Lijie Qiao
Rui Yu
Hongjie Ren
Anshe Zhao
Yang Sun
Aolong Wang
Bin Li
1 more
Mingjun Zhu

doi 10.3389/fphar.2025.1641422

1,349 views

BRIEF RESEARCH REPORT

Published on 30 Jun 2025

Clinical outcomes of pharmacological therapies for heart failure in Black vs. White populations: a meta-analysis of randomized controlled trials of heart failure treatment

Yujia Li
Huilin Tang
Wenxi Huang
Wei-Han Chen
Shao-Hsuan Chang
Jiang Bian
Mustafa M. Ahmed
Stephen E. Kimmel
Jingchuan Guo

doi 10.3389/fcvm.2025.1482311

1,044 views

ORIGINAL RESEARCH

Published on 30 Jun 2025

CLU, FOS, and CXCL8 as diagnostic biomarkers for heart failure progression post-acute myocardial infarction: an integrated RNA-Seq and multi-machine learning study

Jingjing Wei
Peng Yu
Yucai Hu
Lijie Qiao
Bin Li
Haitao Li
Shiyang Xie
Zhengwei Dong
Aolong Wang
3 more
Mingjun Zhu

doi 10.3389/fcvm.2025.1611668

1,300 views

ORIGINAL RESEARCH

Published on 22 Apr 2025

Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation

Yulong Liu
Xinyue Wang
Maomao Zhang
Dan Cheng
Zhenpeng Zhu
Lan Ge
Xiaoyu Cheng

doi 10.3389/fcvm.2025.1561963

1,765 views

ORIGINAL RESEARCH

Published on 14 Apr 2025

Cardiac protection of wogonin in mice with pulmonary fibrosis by regulating Sirt1/ γ-H2AX pathway

Libo Wang
Fei Lin
Runran Miao
Tianhao Zhao
Yuan Liu
Lin Yang
Min Zhang

doi 10.3389/fphar.2025.1551141

1,550 views
2 citations

ORIGINAL RESEARCH

Published on 26 Feb 2025

Beta-blocker administration within 24 hours after admission to the intensive care unit and mortality in critical heart failure patients: a retrospective analysis from the MIMIC-IV database

Linfeng Xie
Jing Chen
Yuanzhu Li
Gang Liu
Jian Shen
Xiang Li
Yuan Yang
Yintao Chen
Suxin Luo
Bi Huang

doi 10.3389/fphar.2025.1514138

1,875 views

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Frontiers in Cardiovascular Medicine

Cardiovascular Pharmacology and Drug Discovery

Participating Journals

Frontiers in Pharmacology
- Cardiovascular and Smooth Muscle Pharmacology
- 4.8 impact factor
- 8.9 citescore

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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Articles

Evaluation of left ventricular systolic function in different subtypes of pediatric acute lymphoblastic leukemia: a case-control study based on two-dimensional speckle tracking

A systematic review and meta-analysis on the efficacy and safety of finerenone in the progression of heart failure

Effects of angiotensin receptor–neprilysin inhibition on myocardial energy metabolism and prognosis in patients with acute myocardial infarction complicated by heart failure

Long-acting relaxin analogues: a novel tool in cardiology

Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission

Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis

Clinical outcomes of pharmacological therapies for heart failure in Black vs. White populations: a meta-analysis of randomized controlled trials of heart failure treatment

CLU, FOS, and CXCL8 as diagnostic biomarkers for heart failure progression post-acute myocardial infarction: an integrated RNA-Seq and multi-machine learning study

Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation

Cardiac protection of wogonin in mice with pulmonary fibrosis by regulating Sirt1/ γ-H2AX pathway

Beta-blocker administration within 24 hours after admission to the intensive care unit and mortality in critical heart failure patients: a retrospective analysis from the MIMIC-IV database

Frontiers in Cardiovascular Medicine

Cardiovascular Pharmacology and Drug Discovery

Participating Journals

Frontiers in Pharmacology

Cardiovascular and Smooth Muscle Pharmacology