Advances in Understanding and Managing Skull Base Pathologies

Skull base pathologies (including lesions at the sellar-parasellar region and in the posterior fossa) encompass a variety of challenging conditions such as tumors, cysts, and vascular disorders, which are difficult to diagnose and treat due to the anatomical complexity of the region. Managing these conditions requires a team of specialists from fields including neurosurgery, neuroradiology, and endocrinology, all working together to navigate the intricacies of this critical area. Despite significant advances in medical and surgical interventions, the diverse and complex nature of these pathologies often complicates treatment strategies, challenging clinicians to adapt and innovate continually.

This Research Topic aims to highlight recent advancements and foster the development of new approaches for diagnosing and treating skull base pathologies in the adult and pediatric populations, with a specific focus on petrous meningiomas and sellar-parasellar lesions. It seeks to bridge the gap between current clinical practices and potential groundbreaking treatments, aspiring to improve patient outcomes through innovative surgical and therapeutic techniques, and enhanced understanding of the diseases’ biology.

To achieve a comprehensive understanding of these complex conditions, we welcome submissions of various types of manuscripts supported by the journal (including Brief Research Reports, Perspectives, Protocols, Systematic Reviews, Mini-Reviews, Original Research, etc.). These manuscripts should explore, but are not limited to, the following themes related to skull base pathologies:
- Diagnostic and clinical progression in the classification of skull base pathologies.
- Innovative surgery and therapy options paving the future for treating petrous meningioma as well as sellar and parasellar lesions.
- Interdisciplinary strategies for managing the complexities of petrous, clival or petroclival meningiomas.
- New findings in the multimodal management of sellar and parasellar lesions.
- Studies on chordoma and chondrosarcoma are also welcome.
- Approaches to tackling treatment-induced complications in skull base pathologies.
- Evaluations of long-term treatment outcomes in patients with skull base disorders.
- Cutting-edge molecular and targeted therapies for treating skull base tumors.
The goal is to collect a wide range of articles that contribute significantly to both the clinical and research aspects of skull base pathologies occurring in the pediatric or adult age, helping establish more effective and sophisticated treatment modalities. We welcome studies on primary tumors as well as systemic cancers that have metastasized to the skull base/sellar-parasellar regions.
Studies that are bioinformatically based and without clinical and/or functional validation will not be considered.

Articles accepted after peer review will be published and appear online as soon as approved for publication.

Register on the collection homepage to participate in this topic.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Review
• Study Protocol
• Systematic Review
• Technology and Code

Keywords: skull base, posterior fossa tumor, meningioma, sellar and parasellar lesions, surgery, radiotherapy, molecular treatments, classification

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.