Unraveling Microbial Interactions: Cross-Kingdom Dynamics and Innovations in Anti-Microbial Probiotics

This research topic seeks to advance the understanding of the complex interplay between microbial species across diverse ecosystems and host environments. Contributions are invited to explore how cross-kingdom interactions—such as bacteria-virus, bacteria-fungi, or virus-fungi relationships—regulate microbial community dynamics, influence disease outcomes, and alter ecological stability. Emphasis will be placed on studies that illuminate the mechanisms underlying microbial synergy, antagonism, and the modulation of host immune responses.

A key focus of this issue is the prospective development of anti-microbial probiotics, an emerging approach that leverages the properties of beneficial microbes to suppress pathogenic organisms. As antimicrobial resistance poses significant global health challenges, such probiotics offer promising solutions by restoring microbial homeostasis without contributing to resistance mechanisms. We welcome submissions that bridge basic and translational research, including clinical studies, ecological applications, and novel methodologies, contributing to innovative solutions for microbiome-targeted interventions.

We welcome high-impact research articles, comprehensive reviews, and concise communications that address the multifaceted interactions within microbial ecosystems.

Areas of interest include:
1. Cross-kingdom interactions involving bacteria, viruses, fungi, and other microorganisms;
2. Molecular mechanisms of microbial cooperation, competition, and pathogen suppression;
3.Innovations in the development and clinical application of anti-microbial probiotics;
4. Microbiome dynamics during disease onset, progression, and recovery;
5. Ecological and clinical implications of microbial networks;

Manuscripts should provide novel insights into microbial interactions with potential for translational impact. All submissions must adhere to the journal’s guidelines.