Novel Approaches to Overcome Drug Resistance in Breast Cancer

The recurrence of breast cancer, often driven by drug resistance, remains a formidable challenge in oncology. Despite significant advancements in targeted therapies and personalized medicine, drug resistance across various treatment modalities, including endocrine therapy and immunotherapy, continues to compromise long-term efficacy and exacerbate tumour aggressiveness. Understanding the molecular underpinnings of drug resistance and developing innovative interventions is critical for improving survival outcomes and reducing recurrence rates.
This Research Topic focuses on the mechanisms driving drug resistance in breast cancer and explores novel strategies to mitigate its impact. We invite researchers to contribute studies that advance our understanding of this critical area, offering insights into overcoming one of the most significant hurdles in breast cancer management. The manuscript topics to cover are but are not limited to:
-Mechanisms of Drug Resistance
-Biomarkers and Diagnostics
-Clinical and Translational Studies
-Real-world evidence on managing treatment-resistant breast cancer.
-Translational research linking laboratory findings to clinical applications.
-Technological Advancements
-Integration of AI and bioinformatics in resistance research.
-Utilization of advanced imaging and genomic tools to study resistance.
This collection aims to foster interdisciplinary collaboration, encouraging breakthroughs that can transform breast cancer management. Together, these studies will contribute to developing more robust and sustainable therapeutic strategies, providing hope for improved patient outcomes. 
Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases) are not suitable for publication in this journal.