Chronic kidney disease (CKD) is a growing global health concern, significantly contributing to morbidity and mortality rates worldwide. Characterized by a gradual decline in kidney function, CKD is influenced by a range of modifiable risk factors, including high blood pressure and blood glucose, obesity, and lifestyle factors such as smoking and alcohol consumption. While advances in treatment and prevention have improved patient outcomes, CKD remains a leading cause of premature death due to its complex interplay with metabolic and cardiovascular conditions.
This Research Topic aims to explore the modifiable risk factors that contribute to CKD progression and identify strategies for early intervention and management. By focusing on preventable and reversible contributors to disease progression, this collection seeks to enhance our understanding of how targeted interventions can slow CKD development and improve patient outcomes.
We invite researchers to submit original research, reviews, and other article types that examine the role of modifiable risk factors in CKD progression, including but not limited to:
• Metabolic and cardiovascular influences on CKD progression
• Lifestyle and dietary interventions for CKD prevention and management
• Hypertension and diabetes control in reducing CKD risk
• Novel therapeutic approaches targeting modifiable risk factors
• Biomarkers for early detection and monitoring of CKD progression
• Inflammation, oxidative stress, and their role in CKD advancement
By compiling cutting-edge research and expert perspectives, this collection aims to advance our understanding of modifiable risk factors in CKD and promote evidence-based strategies to mitigate its progression. We encourage submissions employing multidisciplinary approaches, from molecular mechanisms to clinical and public health interventions, to provide a comprehensive view of this critical issue.
Keywords: Chronic Kidney Disease, Biomarkers, Risk Factors, CKD-Related Mortality, Comorbidities, Metabolic Disorders
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
