Bioactive Natural Compounds and Their Role in Oxidative Stress in Animals

Oxidative stress, an imbalance between the production of reactive oxygen species (ROS) and the ability to neutralize them with antioxidants, significantly impacts animal health and disease development. It influences chronic conditions in animals, such as metabolic disorders, cardiovascular diseases, and age-related issues. This stress affects cells and tissues, making it a pivotal target for nutritional interventions in veterinary medicine.

Emerging research suggests that natural bioactive compounds from plants, fruits, vegetables, fungi, and marine organisms, known for their antioxidant, anti-inflammatory, and cytoprotective properties, could be beneficial in animal nutrition. These compounds may mitigate oxidative stress, enhancing overall health and disease resistance in animals.

This Research Topic explores advancements in applying natural bioactive compounds to improve animal health through oxidative stress management. We invite submissions detailing how these compounds enhance antioxidant defenses, reestablish cellular homeostasis, and influence pathways related to metabolism. Studies on bioavailability, novel delivery systems like nanotechnology, sustainable sourcing, and preclinical applications in animals are particularly welcome.

Topics of interest include:

• Mechanisms by which bioactive compounds modulate oxidative stress in animals.
• Bioavailability challenges and innovations for natural antioxidants in animal nutrition.
• Impact on gene expression and metabolic pathways.
• Formulation strategies like nanotechnology to improve efficacy in animals.
• Comparative studies demonstrating their therapeutic potential in animal health.

By addressing these areas, this Research Topic contributes to advancing animal nutrition and metabolism, emphasizing disease prevention and the development of dietary supplements and treatments.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Keywords: Bioactive substances, Natural compounds, Oxidative stress, Chronic diseases, Reactive oxygen species (ROS)

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.