Hematologic disorders following solid organ transplantation (SOT) represent a critical aspect of post-operative care, with implications ranging from benign anemia to severe conditions like acute myeloid leukemia and post-transplant lymphoproliferative disorders (PTLD). In the post-transplantation phase, patients exhibit a variety of hematologic complications influenced by both infectious and non-infectious factors. These complications contribute to hematological abnormalities and arise due to a myriad of mechanisms such as drug-induced bone marrow suppression or alteration of immune cell subsets due to immunosuppressive therapy. The heightened risk of opportunistic infections and potential graft rejection posed by these disorders necessitates meticulous management and monitoring.
This Research Topic aims to deepen understanding and update knowledge on the breadth of hematologic disorders that can occur after SOT, how they impact patient health and transplant success, and to outline effective management strategies. Given the complex interplay of immunosuppression, patient's pre-existing conditions, and the nature of the transplanted organ, it is crucial to approach diagnosis and treatment with a nuanced understanding of these variables.
To gather further insights into this complex area, we welcome submissions that extend across various aspects of hematological disorders in post-transplant patients. These include, but are not limited to, the following themes:
• Relationship between hematological treatment and immunosuppressive therapy
• Hematologic Disorders and onset of post-transplant opportunistic infections
• Autoimmune hemolytic and hemophagocytic disorders after SOT
• Post-transplant lymphoproliferative diseases (PTLD)
• Myeloid neoplasms after organ transplantation
• Influence of post-Tx hematological diseases on graft and patient’s survival
We welcome the submissions of Original Research, Review, and Case Report articles focusing on these key areas.
Keywords: Solid organ transplantation, Haematological disorders, Immunosuppression, Clinical presentation, Diagnostic procedures, Therapy
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
