Fish immunology has increasingly become a critical research area due to the ecological and economic importance of fish, their susceptibility to infectious diseases, and their potential as models for immune system evolution and biomedical studies. While there is significant evidence illustrating diverse immune mechanisms in fish, many aspects of their immune regulation, response to emerging pathogens, and evolutionary adaptations remain poorly understood. Recent studies have identified key features of innate and adaptive immunity, signaling pathways, genetic regulation, and pathogen-host interactions in fish species. Nevertheless, a detailed understanding is still lacking regarding the comparative variability of immune strategies among different fish lineages, their evolutionary origins, and how environmental challenges influence immune dynamics.
This Research Topic aims to explore the most recent advances in understanding the complexities and evolutionary dynamics of immune responses specifically among fish species. We particularly aim to highlight studies addressing essential questions about immune regulation, genetic factors involved, host-pathogen interactions, immune adaptation, disease resistance, and vaccines targeting relevant pathogens that affect fish health.
To gather further insights within the boundaries of fish immunology, we welcome articles addressing, but not limited to, the following themes:
• Molecular mechanisms of innate and adaptive immune responses in fish
• Comparative immunological studies among different fish species
• Evolutionary perspectives on immune system adaptations in fish
• Genetic and epigenetic regulation of immune responses in fish
• Fish pathogen interactions, disease resistance mechanisms, and vaccine development
• Environmental influences affecting fish immune functions and responsiveness to diseases
Accepted article types include Original Research, Reviews, Brief Research Reports, Mini Reviews, Methods Articles, and Perspectives.
Article types and fees
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Brief Research Report
Case Report
Clinical Trial
Editorial
FAIR² Data
General Commentary
Hypothesis and Theory
Methods
Mini Review
Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.
Article types
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
