Cardio-Oncology in the Era of Precision Medicine: Risk Stratification, Surveillance, and Cardioprotection Across the Cancer Continuum

Cardio-oncology has emerged as a pivotal field due to the rising incidence of cardiovascular complications among cancer patients and survivors. As oncologic treatments evolve from traditional cytotoxic agents to innovative targeted therapies and immunotherapies, the intricacies of managing cardiovascular health in this population intensify. This expansion necessitates precise cardiovascular risk stratification, early detection of potential cardiotoxicities, and the development of tailored cardioprotective approaches to improve patient outcomes. Literature highlights significant advancements in using genomic, proteomic, and metabolomic biomarkers, coupled with sophisticated imaging techniques and machine learning models, for refined risk prediction and toxicity monitoring. However, existing gaps in translating these tools into routine clinical practice, especially in varied demographic contexts, underscore the need for continued investigation.

This Research Topic aims to probe contemporary advancements and address unmet needs in cardio-oncology, particularly focusing on personalized strategies throughout the continuum of cancer care. Core objectives include the evaluation of novel biomarkers and technologies in risk prediction, the exploration of innovative cardioprotective interventions, and the assessment of disparities in outcomes and healthcare access among vulnerable populations. Furthermore, interdisciplinary contributions are sought to bridge the knowledge gap between cardiology, oncology, pharmacology, nursing, and public health.

To gather further insights in the advancement of cardio-oncology care, we welcome articles addressing, but not limited to, the following themes:

o Precision-based cardiovascular risk assessment methodologies

o Innovative cardioprotective interventions across different cancer types and stages

o Implementation of cardio-oncology practices in real-world clinical settings

o Survivorship and evaluation of long-term cardiovascular outcomes in diverse populations

o Strategies to improve equity in access to cardio-oncology services

We seek high-quality original research, reviews, clinical trials, and perspectives that contribute to a better understanding and implementation of precision medicine and equitable practices in cardio-oncology care.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Curriculum, Instruction, and Pedagogy
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Curriculum, Instruction, and Pedagogy
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Review
• Study Protocol
• Systematic Review

Keywords: Cardio-oncology, precision medicine, cardiovascular complications, cancer patients, risk stratification, cardioprotection, cytotoxic agents, targeted therapies, immunotherapies, biomarkers, genomics, proteomics, metabolomics, advanced imaging techniques

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.