Biotechnological Breakthroughs in Viral Pathogen Detection and Diagnostics

The field of biotechnology is rapidly advancing to address the urgent need for effective viral detection, as exemplified by the COVID-19 pandemic. This highlighted the necessity for technologies capable of accurately identifying viral pathogens early in the infection cycle and directly at the point of care. Driven by the pressing challenge of managing infectious outbreaks, recent innovations have transformed viral diagnostics across various applications, from clinical and environmental monitoring to epidemiological surveillance. This surge in innovation has resulted in a plethora of new tools and methodologies designed to significantly enhance viral detection and tracking.

This Research Topic aims to assemble pioneering research on biotechnological advances revolutionizing viral pathogen identification and monitoring. It will stress the convergence of biology, engineering, and data science as a foundation for next-generation diagnostics. Specific focuses include the development of novel molecular diagnostics, like real-time PCR, isothermal amplification methods, and CRISPR-based systems, which are gaining traction due to their programmability and efficiency. Furthermore, the role of biosensors, nanotechnologies, and AI-driven diagnostic platforms offers a comprehensive perspective on current advancements, including their impact on speed, sensitivity, and cost-effectiveness.

To gather further insights into these dynamic developments, we welcome articles addressing, but not limited to, the following themes:

• Molecular diagnostic platforms
• Biosensors and nanotechnology-enabled detection systems
• Lab-on-a-chip and microfluidic diagnostics
• Point-of-care and field-deployable devices
• AI and data-driven diagnostic approaches
• Multiplexed and high-throughput viral detection
• Environmental and zoonotic viral surveillance technologies

By pooling diverse contributions within this field, this Research Topic will highlight how biotechnology could enhance global preparedness and response to viral threats, ultimately contributing to more resilient and adaptable public health systems.

We invite submissions that present original research, reviews, and case studies focused on the development, validation, and application of novel biotechnological tools for viral detection.