Advancements in Biosensing Technologies for Diagnosis and Monitoring of Microbial Infections

Recent breakthroughs in biosensing technologies have significantly enhanced the rapid detection, diagnosis, and real-time monitoring of microbial infections, offering promising solutions for clinical and public health applications. These novel biosensors—ranging from point-of-care devices to sophisticated, high-throughput platforms—leverage cutting-edge approaches such as nanomaterials, microfluidics, and artificial intelligence to improve sensitivity, specificity, and turnaround time. The integration of these tools has the potential to revolutionize microbial diagnostics by enabling earlier intervention, individualized treatment, and better epidemiological surveillance.

This Research Topic seeks contributions that highlight innovative methodologies, translational research, and clinical applications in biosensing technologies. We welcome original research, review articles, and technological reports focusing on the detection of bacterial, viral, fungal, and parasitic pathogens, as well as studies that address challenges such as multiplexing, miniaturization, and deployment in resource-limited settings. Our goal is to foster a multidisciplinary dialogue that accelerates the adoption and optimization of biosensors for improved infectious disease management.

To gather further insights in this complex field, we welcome articles addressing, but not limited to, the following themes:
- Emerging biosensing platforms for rapid and sensitive detection of microbial pathogens
- Integration of biosensing with digital health and data analytics for real-time monitoring
- Applications in clinical diagnostics, point-of-care testing, and field surveillance
- Advances in miniaturization and development of portable biosensors
- Strategies for multiplexed detection and differentiation of co-infections
- Novel biorecognition elements (e.g., aptamers, antibodies, CRISPR-based systems)
- Overcoming challenges in specificity, robustness, and cost-effectiveness
- Implementation in low-resource and decentralized settings
- Regulatory, ethical, and translational considerations for clinical deployment

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Clinical Trial
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Clinical Trial
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Systematic Review

Keywords: Biosensing, Microbial Infections, Diagnostics, Point-of-Care, Nanotechnology, Microfluidics, Pathogen Detection, CRISPR, Rapid Testing, Infection Monitoring

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.