Celebrating 45 Years of the Chilean Society of Pharmacology, Volume II

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ORIGINAL RESEARCH

Published on 17 Apr 2026

The entactogen MDMA (3,4-methylenedioxymethamphetamine, “Ecstasy”) disrupts helping behaviour while reinforcing electrophysiological indicators of potentially associated synaptic plasticity in male Sprague-Dawley rats

  • Patricio Sáez-Briones
  • Amanda Silva-Rodríguez
  • Michelle Morales-Vidal
  • Yaniz Sepúlveda-Fernández
  • Dorys Jara-Clen
  • Michelle Castro-Choapa
  • Pablo Livacic-Rojas
  • Darío Martínez-Afani
  • Bruce K. Cassels
  • 3 more
  • Alejandro Hernández
doi 10.3389/fphar.2026.1779772
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