LS
lea smircic duvnjak
Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital
Zagreb, Croatia
About this Research Topic
This Research Topic is currently accepting articles, but is closing soon.
Background
Type 1 diabetes has traditionally been characterized by autoimmune β-cell destruction and insulin dependence, yet a growing body of evidence reveals substantial metabolic heterogeneity among affected individuals. The coexistence of metabolic syndrome features, including insulin resistance, dyslipidemia, and obesity poses additional clinical challenges, complicating both glycemic control and long-term outcomes. Moreover, rapid weight loss interventions and modern diabetes technologies are reshaping disease management, raising important questions about metabolic adaptation, durability of remission, and cardiovascular risk.
This Research Topic aims to explore the evolving clinical and metabolic landscape of Type 1 diabetes, focusing on patients who present with overlapping features of metabolic syndrome or undergo intensive therapeutic interventions. Contributions are encouraged that address how advanced technologies, body-composition changes, and metabolic remodeling influence disease progression and complications. Studies integrating clinical, biochemical, and mechanistic insights are particularly welcome to advance individualized approaches in Type 1 diabetes care.
Areas of interest include, but are not limited to:
- Interaction between Type 1 diabetes and metabolic syndrome
- Long-term metabolic consequences of rapid or intensive weight loss in Type 1 diabetes.
- Clinical evaluation of advanced technologies in demanding or complex Type 1 diabetes cases.
- Markers of metabolic resilience and predictors of treatment response.
- Cardiometabolic and renal outcomes in metabolically complex Type 1 diabetes.
- Clinical frameworks for integrating metabolic assessment into routine Type 1 diabetes care.
Article types and fees
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
- Case Report
- Clinical Trial
- Editorial
- FAIR² Data
- General Commentary
- Hypothesis and Theory
- Methods
- Mini Review
- Opinion
Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.
Article types
This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:
- Case Report
- Clinical Trial
- Editorial
- FAIR² Data
- General Commentary
- Hypothesis and Theory
- Methods
- Mini Review
- Opinion
- Original Research
- Perspective
- Policy and Practice Reviews
- Review
- Systematic Review
- Technology and Code
Keywords: Type 1 diabetes, metabolic syndrome, insulin resistance, dyslipidemia, obesity, weight loss interventions, advanced technologies, metabolic remodeling, cardiovascular risk, individualized care
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
