Research Topic

The Brain–Gut–Microbiome Network in Metabolic Regulation and Dysregulation

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About this Research Topic

The very nature of endocrinology has undergone major paradigm shifts over the last few decades with the discovery of endocrine functions by organs not hitherto considered as endocrine organs, such as fat, the gut and the brain, both as metabolism regulators and targets of regulation through organ cross-talk. ...

The very nature of endocrinology has undergone major paradigm shifts over the last few decades with the discovery of endocrine functions by organs not hitherto considered as endocrine organs, such as fat, the gut and the brain, both as metabolism regulators and targets of regulation through organ cross-talk. In addition, a major conceptual revolution has taken place in the last few years with the explosion of interest in the role of the symbiosis between animals and the microbes they host, primarily in the gut (microbiome), and in metabolic regulation.

This Research Topic will attempt to paint a coherent picture of the interactions between the brain, the gut and the microbiome as a crucial network involved in metabolic regulation as well as its disturbances in obesity, type 2 diabetes and neurodegenerative disorders.

This Research Topic emanates from the recent 43rd Symposium on Hormones and Cell Regulation held in Mont Sainte Odile, Alsace, France in October 2018, where 27 leading investigators in the field presented cutting-edge research. Short lectures and posters by students and young investigators were also featured. The Symposium was sponsored by the European Society for Endocrinology.

Speakers and participants are welcome to contribute to the Research Topic which is also open for spontaneous submissions.

Picture of Mont St Odile: Permission granted by Claude Massart.


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