Allogeneic transplantation is still deemed the gold standard solution for end-stage organ failure; however, donor organ shortages have led to extended waiting lists for organ transplants. In order to overcome the lack of donors, the development of new therapeutic options looks like the best strategy to provide patients with an alternative to transplant. In the last several years, organ bioengineering has been extensively explored to provide transplantable tissues or whole organs with the final goal of creating a three-dimensional growth microenvironment mimicking the native structure. Tissue and organ engineering is the interdisciplinary therapeutic sector that aims to meet the medical needs related to tissues and organs by recreating them, engineering them or promoting their repair; thus restoring, recreating or improving their original biological functions. We may expect that such technologies will have a rapid translation to clinical surgical protocols, impacting on the surgical science.
The purpose of the present call is to collect the recent developments and undergoing studies in bioengineering, tissue and organ regeneration taking into account: biological and synthetic scaffolds; animal and human tissue decellularization; scaffold recellularization; 3D bioprinting; organoid technology.
The other goal is to define future possible clinical applications in regenerative medicine for tissue engineering considering how can this impact on surgery/hospitals/surgical staff/new skills required for surgeons and surgical curricula.
The Research Topic welcomes manuscripts on organ and tissue replacement, tissue bioengineering (discoveries, design and technologies), 3D bio printing, translation of tissue and organ engineering into clinical setting in surgery, organs-on-a-chip.
Original article, review and perspectives are welcomed.
Allogeneic transplantation is still deemed the gold standard solution for end-stage organ failure; however, donor organ shortages have led to extended waiting lists for organ transplants. In order to overcome the lack of donors, the development of new therapeutic options looks like the best strategy to provide patients with an alternative to transplant. In the last several years, organ bioengineering has been extensively explored to provide transplantable tissues or whole organs with the final goal of creating a three-dimensional growth microenvironment mimicking the native structure. Tissue and organ engineering is the interdisciplinary therapeutic sector that aims to meet the medical needs related to tissues and organs by recreating them, engineering them or promoting their repair; thus restoring, recreating or improving their original biological functions. We may expect that such technologies will have a rapid translation to clinical surgical protocols, impacting on the surgical science.
The purpose of the present call is to collect the recent developments and undergoing studies in bioengineering, tissue and organ regeneration taking into account: biological and synthetic scaffolds; animal and human tissue decellularization; scaffold recellularization; 3D bioprinting; organoid technology.
The other goal is to define future possible clinical applications in regenerative medicine for tissue engineering considering how can this impact on surgery/hospitals/surgical staff/new skills required for surgeons and surgical curricula.
The Research Topic welcomes manuscripts on organ and tissue replacement, tissue bioengineering (discoveries, design and technologies), 3D bio printing, translation of tissue and organ engineering into clinical setting in surgery, organs-on-a-chip.
Original article, review and perspectives are welcomed.