In the last two decades, stem cells have been extensively studied for use as cellular therapy for the treatment of different conditions. However, mesenchymal stromal/stem cells (MSCs) and induced-pluripotent stem cells (iPSCs) have also been used as a model to study different disorders, because of their ability to differentiate into other types of cells, resembling the in vivo physiological environment. This has made research in MSCs and iPSCs to be at the forefront of research that will lead to understanding of diseases and their related biological processes.
The goal of this Article Collection is to bring together studies that have used MSCs and iPSCs to provide new insights in the understanding of important biological processes in different conditions and disorders. This will include reviews and original research studies using primary and commercial cell lines of animal or human origin to mimic disease models that seeks to provide new perspective and/or add new body of knowledge on the importance of using these stem cells as suitable models in understanding disease related processes. This will generate great interest among researchers, scientists and entrepreneurs that will contribute in the advancement of this field.
This Research Topic aims to give a perspective on how this field is advancing. It welcomes all article types accepted by the journal (e.g., original research studies, reviews, methods, perspectives, etc.) on topics that makes use of MSCs or iPSCs as models to investigate disease mechanisms or other biological processes.
We hope that this Article Collection is of great interest to researchers and readers that work in the field of these kind of stem cells and use them to deepens their knowledge in particular disorders, but also to investigators interested in understanding the physiological processes in regular and non-disease condition. This will also attract attention from private and public enterprises with shared interest in leveraging this knowledge for commercialization purposes.
In the last two decades, stem cells have been extensively studied for use as cellular therapy for the treatment of different conditions. However, mesenchymal stromal/stem cells (MSCs) and induced-pluripotent stem cells (iPSCs) have also been used as a model to study different disorders, because of their ability to differentiate into other types of cells, resembling the in vivo physiological environment. This has made research in MSCs and iPSCs to be at the forefront of research that will lead to understanding of diseases and their related biological processes.
The goal of this Article Collection is to bring together studies that have used MSCs and iPSCs to provide new insights in the understanding of important biological processes in different conditions and disorders. This will include reviews and original research studies using primary and commercial cell lines of animal or human origin to mimic disease models that seeks to provide new perspective and/or add new body of knowledge on the importance of using these stem cells as suitable models in understanding disease related processes. This will generate great interest among researchers, scientists and entrepreneurs that will contribute in the advancement of this field.
This Research Topic aims to give a perspective on how this field is advancing. It welcomes all article types accepted by the journal (e.g., original research studies, reviews, methods, perspectives, etc.) on topics that makes use of MSCs or iPSCs as models to investigate disease mechanisms or other biological processes.
We hope that this Article Collection is of great interest to researchers and readers that work in the field of these kind of stem cells and use them to deepens their knowledge in particular disorders, but also to investigators interested in understanding the physiological processes in regular and non-disease condition. This will also attract attention from private and public enterprises with shared interest in leveraging this knowledge for commercialization purposes.