Wicked Problem | List of Frontiers open access articles

Original Research

Published on 18 Aug 2025

Development and validation of a LASSO-based predictive model for inadvertent hypothermia in ICU patients

in Intensive Care Medicine and Anesthesiology

Xueting Wang
Yuxuan Chen
Lan Hua
Dongmei Wang
Xia Zhang
Lianhong Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1596030

Systematic Review

Published on 18 Aug 2025

A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis

in Spine Conditions

Michael R. Kann
Rahul Ramanathan
Christopher Gonzalez
Timothy Edwards
Christian Cisneros
Christopher J. Como
Trudy Zou
Sarah Lutes
Julia Chagas
Michael J. Spitnale

Frontiers in Musculoskeletal Disorders

doi 10.3389/fmscd.2025.1597288

214 views

Perspective

Published on 18 Aug 2025

Is maternal SARS-CoV-2 infection in the first trimester associated with congenital heart defects?

in Pediatric Cardiology

Athina Samara
Conrado Milani Coutinho
Paul T. Heath
Asma Khalil

Frontiers in Pediatrics

doi 10.3389/fped.2025.1643423

376 views

Review

Published on 18 Aug 2025

Red blood cell extracellular vesicles: new frontiers in hematological biomarker discovery

in Hematology

Urja Joshi
Linz-Buoy George
Hyacinth Highland

Frontiers in Medicine

doi 10.3389/fmed.2025.1644077

133 views

Editorial

Published on 18 Aug 2025

Editorial: Exploring KLF4’s role in immune cell function and disease progression

in Cancer Immunity and Immunotherapy

H. Daniel Lacorazza
Walden Ai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672030

150 views

Editorial

Published on 18 Aug 2025

Editorial: Mindfulness and resilience in the digital age: addressing cyberattacks and enhancing mental health and performance among adults

in Public Mental Health

Ali Nawaz Khan
Naseer Abbas Khan
Ali Ahmad

Frontiers in Public Health

doi 10.3389/fpubh.2025.1671991

151 views

Original Research

Published on 18 Aug 2025

From gut to proteomics: the impact of Roseburia intestinalis on post-translational modifications in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Lu Li
Yong Zhang
Qianqian Wu
Ziyu Jin
Hongbing Xia
Huili Wu
Kunkun Li
Lihong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1599183

Case Report

Published on 18 Aug 2025

Long-term survival with multidisciplinary treatment in metastatic sarcomatoid renal cell carcinoma: a case report and literature review

in Genitourinary Oncology

Xin Li
Weijia Wang
Lingjun Meng
Honglu Liang

Frontiers in Oncology

doi 10.3389/fonc.2025.1600376

140 views

Mini Review

Published on 18 Aug 2025

The impact of aberrant lipid metabolism on the immune microenvironment of gastric cancer: a mini review

in Systems Immunology

Shuangyu Chen
Wenqian Chen
Tinghui Xu
Jiayang Li
Jianghao Yu
Yibo He
Shengliang Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639823

178 views

Review

Published on 18 Aug 2025

A review of the participation of DDIT4 in the tumor immune microenvironment through inhibiting PI3K-Akt/mTOR pathway

in Cancer Immunity and Immunotherapy

Yunshu Jiao
Yang Xiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1595463

165 views

Opinion

Published on 18 Aug 2025

Urban physical activity for neurogenesis: infrastructure limitations

in Environmental Health and Exposome

Mohamed Hesham Khalil

Frontiers in Public Health

doi 10.3389/fpubh.2025.1638934

233 views

Original Research

Published on 18 Aug 2025

Ruxolitinib and decitabine plus a busulfan–cyclophosphamide conditioning regimen for relapse prophylaxis in patients with high-risk acute myeloid leukemia or myelodysplastic syndromes

in Alloimmunity and Transplantation

Yujun Wei
Songhua Luan
Lu Wang
Lili Wang
Fei Li
Xiangshu Jin
Ruoling Yang
Kun Qian
Bo Peng
Jingwen Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586512

253 views

Case Report

Published on 18 Aug 2025

Bilateral breast metastases from rectal malignant melanoma: case report and literature review

in Gastrointestinal Cancers: Colorectal Cancer

Hui Liu
Qian Liu
Linshen Zhang
Qinghua Liu
Hao Cheng
Jian Liao
Zhaohong Chen
Dingyu Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1565838

115 views

Original Research

Published on 18 Aug 2025

Insulin injection knowledge, attitude, and practice of community nurses in a mountainous area of southwest Zhejiang in China: a multi-center cross-sectional study

in Clinical Diabetes

Xuefen Lan
Simin Zheng
Xiaozhen Ji
Ling Chen
Ling Zhou
Bin Ye
Qingqing Zhu
Xiaojia Zheng
Shunfei Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1501992

254 views

Systematic Review

Published on 18 Aug 2025

Comparative effectiveness of nerve block strategies for preventing postherpetic neuralgia in thoracic herpes zoster: a network meta-analysis

in Neurorehabilitation

Wensheng Lu
Shengze He
Qi Liu
Yaozu Gu
Jie Bai

Frontiers in Neurology

doi 10.3389/fneur.2025.1612871

217 views

Case Report

Published on 18 Aug 2025

Case Report: Dramatic response to entritinib in a patient with gastrointestinal stromal tumor positive for NTRK3 fusion

in Cancer Molecular Targets and Therapeutics

Guomin Dong
Pengyu Han
Zhiyun Zhang
Qian Ge
Jian Jiang
Suoni Li
Jiequn Ma
Jie Bai
Hui Wei
Zheng Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1588950

136 views

Articles

Development and validation of a LASSO-based predictive model for inadvertent hypothermia in ICU patients

A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis

Is maternal SARS-CoV-2 infection in the first trimester associated with congenital heart defects?

Red blood cell extracellular vesicles: new frontiers in hematological biomarker discovery

Editorial: Exploring KLF4’s role in immune cell function and disease progression

Editorial: Mindfulness and resilience in the digital age: addressing cyberattacks and enhancing mental health and performance among adults

From gut to proteomics: the impact of Roseburia intestinalis on post-translational modifications in colorectal cancer

Long-term survival with multidisciplinary treatment in metastatic sarcomatoid renal cell carcinoma: a case report and literature review

The impact of aberrant lipid metabolism on the immune microenvironment of gastric cancer: a mini review

A review of the participation of DDIT4 in the tumor immune microenvironment through inhibiting PI3K-Akt/mTOR pathway

Urban physical activity for neurogenesis: infrastructure limitations

Ruxolitinib and decitabine plus a busulfan–cyclophosphamide conditioning regimen for relapse prophylaxis in patients with high-risk acute myeloid leukemia or myelodysplastic syndromes

Bilateral breast metastases from rectal malignant melanoma: case report and literature review

Insulin injection knowledge, attitude, and practice of community nurses in a mountainous area of southwest Zhejiang in China: a multi-center cross-sectional study

Comparative effectiveness of nerve block strategies for preventing postherpetic neuralgia in thoracic herpes zoster: a network meta-analysis

Case Report: Dramatic response to entritinib in a patient with gastrointestinal stromal tumor positive for NTRK3 fusion