CORRECTION article

Front. Immunol., 17 July 2020

Sec. Microbial Immunology

Volume 11 - 2020 | https://doi.org/10.3389/fimmu.2020.01601

Corrigendum: Mycobacterium tuberculosis Infection-Driven Foamy Macrophages and Their Implications in Tuberculosis Control as Targets for Host-Directed Therapy

  • 1. Department of Microbiology, Institute for Immunology and Immunological Diseases, Brain Korea 21 Program for Leading Universities and Students (PLUS) Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea

  • 2. Department of Life Science, Research Institute for Natural Sciences, College of Natural Sciences, Hanyang University, Seoul, South Korea

Article metrics

View details

3

Citations

2,1k

Views

816

Downloads

In the original article, incorrect information and references were included in InteractionBetween Mtb and Mtb–Driven Foamy Macrophages, sub-section Characteristics ofMtb-infected Foamy Macrophages and the Utilization of Their Lipids by Mtb, Paragraph 3:

A reference in the sentence “Furthermore, it has been suggested the use of lipids in host cells is related to dormancy of Mtb.” was incorrectly added as “Jaisinghani N, Dawa S, Singh K, Nandy A, Menon D, Bhandari PD, et al. Necrosis driven triglyceride synthesis primes macrophages for inflammation during Mycobacterium tuberculosis infection. Front Immunol. (2018) 9:1490. doi: 10.3389/fimmu.2018.01490.” This should be deleted.

In addition, there was a further error within the same paragraph:

“The region of difference 1 protein in Mtb contributes to increasing the levels of intracellular triglycerides in Mtb by enhancing the expression of diacylglycerol O-acyltransferase, a key enzyme in triglyceride synthesis (68).”

The text should be substituted with the following:

“The region of difference 1 in pathogenic mycobacteria may contribute to the interaction between diacylglycerol O-acyltransferase, a key enzyme in triglyceride synthesis, and lipid droplets of mycobacteria to generate intracellular lipid inclusions.” This statement is supported by the reference “Barisch C, Soldati T. Mycobacterium marinum degrades both triacylglycerols and phospholipids from its dictyostelium host to synthesise its own triacylglycerols and generate lipid inclusions. PLoS Pathog. (2017) 13:e1006095. doi: 10.1371/journal.ppat.1006095”.

The authors apologize for these errors and state that the revisions do not change the scientific conclusions of the article in any way. The original article has been updated.

References

  • 68.

    BarischCSoldatiT. Mycobacterium marinum degrades both triacylglycerols and phospholipids from its dictyostelium host to synthesise its own triacylglycerols and generate lipid inclusions. PLoS Pathog. (2017) 13:e1006095. 10.1371/journal.ppat.1006095

Summary

Keywords

Mycobacterium tuberculosis, foamy macrophage, tuberculosis, immune responses, lipid metabolism, lung inflammation, host-directed therapy

Citation

Shim D, Kim H and Shin SJ (2020) Corrigendum: Mycobacterium tuberculosis Infection-Driven Foamy Macrophages and Their Implications in Tuberculosis Control as Targets for Host-Directed Therapy. Front. Immunol. 11:1601. doi: 10.3389/fimmu.2020.01601

Received

08 June 2020

Accepted

16 June 2020

Published

17 July 2020

Approved by

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Volume

11 - 2020

Updates

Copyright

*Correspondence: Sung Jae Shin

This article was submitted to Microbial Immunology, a section of the journal Frontiers in Immunology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Outline

Cite article

Copy to clipboard


Export citation file


Share article

Article metrics