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Front. Nutr. | doi: 10.3389/fnut.2018.00073

A Clinical Study of Ninjinyoeito with Regard to Frailty

 Naoya Sakisaka1*, Kazuo Mitani2, Sadahiro Sempuku3, Tamaki Imai4, Yoshinori Takemoto5, Hiroaki Shimomura6 and Takahisa Ushiroyama7
  • 1Sakisaka Clinic, Japan
  • 2Mitani Family Clinic, Japan
  • 3Sempuku Clinic, Japan
  • 4Imai Clinic, Japan
  • 5Takemoto Clinic, Japan
  • 6Shimomura Clinic of Internal Medicine, Japan
  • 7Osaka Medical College Health Science Clinic, Japan

Frailty in older people is strongly associated with poor nutrition, which is particularly important in the present day super-aging society. This study initially investigated a number of cases of frailty where there was a speedy recovery following administration of a dual deficiency of qi and blood preparation, ninjin’yoeito (NYT), formulated for frail patients who suffer from kiketuryokyo status. Based on these observations, a more extensive investigation involving a greater number of cases was completed. The findings of the effects of NYT on frailty are reported here.

Keywords: Ninjin’yoeito, Frailty, Sarcopenia, Kampo, elder, muscle quality

Received: 01 Jun 2018; Accepted: 01 Aug 2018.

Edited by:

Akio Inui, Kagoshima University Graduate School of Medical and Dental Sciences, Japan

Reviewed by:

Masayuki Kashima, Japanese Red Cross Kumamoto Hospital, Japan
Naotoshi Shibahara, Institute of Natural Medicine, University of Toyama, Japan  

Copyright: © 2018 Sakisaka, Mitani, Sempuku, Imai, Takemoto, Shimomura and Ushiroyama. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: MD. Naoya Sakisaka, Sakisaka Clinic, Osaka, 547-0047, Japan,