Original Research ARTICLE
Durian Fruits Discovered as Superior Folate Sources
- 1Technische Universität München, Germany
- 2National University of Singapore, Singapore
- 3The University of Queensland, Australia
Durian (Durio zibethinus) is a tropical fruit grown in Southeast Asia and highly appreciated by consumers throughout Asia. Folates are a group of vitamins and are essential nutrients for humans. Here we present the folate analysis of different durian cultivars as well as diverse durian products. An LC-MS/MS method and the application of a stable isotope dilution assay was used for quantitation of the folate vitamers 5-methyltetrahydrofolate, 5-formyltetrahydrofolate, 10-formylfolate, tetrahydrofolate and pteroylmonoglutamic acid by using [13C5]-labeled internal standards. Total folates varied from 175 to 440 µg/100 g for durian arils and from 15.0 to 417 µg/100 g for durian products. These contents are extraordinarily high compared to other fruits and may be correlated to the upregulated methionine biosynthesis pathway reported recently. In summary, the tropical fruit durian can be considered as a very rich dietary source of natural folates.
Keywords: Stable isotope dilution assay, LC-MS/MS, Folate, Durian, tropical fruit
Received: 31 Aug 2018;
Accepted: 09 Nov 2018.
Edited by:Eduardo Dellacassa, Universidad de la República, Uruguay
Reviewed by:Yun Ping Neo, Taylor's University, Malaysia
Kin Weng Kong, University of Malaya, Malaysia
Copyright: © 2018 Striegel, Chebib, Dumler, Lu, Huang and Rychlik. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Prof. Michael Rychlik, Technische Universität München, Munich, Germany, email@example.com