Sec. Cancer Immunity and Immunotherapy
Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.927917
Corrigendum: Anti-Tumoral Effect and Action Mechanism of Exosomes Derived From Toxoplasma gondii-Infected Dendritic Cells in Mice Colorectal Cancer
- 1Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China
- 2Key Laboratory of Animal Parasitology of Ministry of Agriculture, Laboratory of Quality and Safety Risk Assessment for Animal Products on Biohazards (Shanghai) of Ministry of Agriculture, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China
- 3School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China
- 4Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt
A Corrigendum on:
Anti-Tumoral Effect and Action Mechanism of Exosomes Derived From Toxoplasma gondii-Infected Dendritic Cells in Mice Colorectal Cancer
By Zhu S, Lu J, Lin Z, Abuzeid AMI, Chen X, Zhuang T, Gong H, Mi R, Huang Y, Chen Z and Li G (2022). Front. Oncol. 12:870528. doi: 10.3389/fonc.2022.870528
In the original article, there was a mistake in Figure 2 as published. 1. Figure 2A (left) missed to indicate the corresponding groups for the panels. The corresponding groups are now correctly indicated. 2. Figure 2B: The representative flow cytometry plot was repeated two times (same flow cytometry image shown in the third column). The flow cytometry image are the results of flow cytometry detection of anti-CD86-PC7 in the Me49 group.We replaced the lower flow cytometry image in the third column with a representative flow-cytometry plot of anti-CD206-APC in the Me49 group. The corrected Figure 2 appears below.
Figure 2 Me49-DC-Exo inhibited tumor growth in mouse and regulated macrophage polarization. (A) On day 4 after treatment, the IVIS imager detected bioluminescence images in tumors of mouse and quantified the bioluminescence signal intensity of each tumor in mouse. (B) Flow cytometry was used to label CD86 + or CD206 +, and CD45 + CD11b + F4/80 + macrophages in blood of mice injected with DC-Exo and Me49-DC-Exo were stained to detect the percentage of CD86+ CD206 − M1 macrophages and CD86 − CD206 + M2 macrophages. (C) mRNA levels of M1 macrophage specific genes (INOS, TNF-a, and IRF5) and M2 macrophage specific genes (TGM2, Arg-1 and IL10) in blood of tumor-bearing mice injected intratumorally with PBS, DC-Exo and Me49-DC-Exo were detected by qRT-PCR. The data were expressed as mean ± standard deviation, and the independent sample t-test was used to compare the statistical differences between two groups. ns (p ≥ 0.05), *p < 0.05, **p < 0.01, ***p < 0.001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: Toxoplasma gondii, dendritic cells, exosome, miRNA, macrophage, miR-155-5p
Citation: Zhu S, Lu J, Lin Z, Abuzeid AMI, Chen X, Zhuang T, Gong H, Mi R, Huang Y, Chen Z and Li G (2022) Corrigendum: Anti-Tumoral Effect and Action Mechanism of Exosomes Derived From Toxoplasma gondii-Infected Dendritic Cells in Mice Colorectal Cancer. Front. Oncol. 12:927917. doi: 10.3389/fonc.2022.927917
Received: 25 April 2022; Accepted: 31 May 2022;
Published: 21 June 2022.
Edited and reviewed by:Anil Shanker, Meharry Medical College, United States
Copyright © 2022 Zhu, Lu, Lin, Abuzeid, Chen, Zhuang, Gong, Mi, Huang, Chen and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Guoqing Li, email@example.com; Zhaoguo Chen, firstname.lastname@example.org; Zhibing Lin, email@example.com