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CLINICAL TRIAL article

Front. Psychiatry, 06 June 2023
Sec. Addictive Disorders
This article is part of the Research Topic Exploring Prevention Strategies and Treatment in Addictive Disorders View all 9 articles

Pilot data findings from the Gothenburg treatment for gaming disorder: a cognitive behavioral treatment manual

  • 1Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
  • 2Department of Addiction and Dependency, Sahlgrenska University Hospital, Gothenburg, Sweden

Background: Gaming disorder (GD) is a new diagnosis included in the latest edition of the International Classification of Disease −11. Recently conducted international studies suggest a prevalence rate close to 2% for GD, highlighting the need for effective treatments for this patient population. Internationally there are few studies investigating effective treatments specifically designed for this condition. In this pilot study, we wanted to test a newly developed method, the Gothenburg Treatment for Gaming Disorder (GOT-TO-GO) manual; a 15-week cognitive behavioral therapy treatment for GD.

Method: This study utilized a single group design with pretest, post-test and a three- and six-month follow-up, with measures of severity of GD and mood. The participants (n = 28) were treatment-seeking adults with GD, aged 17 to 49 years.

Results: The results show a statistically significant decrease in symptoms of GD after treatment. Hours of gaming per week also decreased concomitantly with a 100% increase in non-gaming leisure hours. The decrease in symptoms of GD was maintained at the 3-months follow-up after treatment. Correspondingly we saw a decrease in both depression and anxiety that also was upheld 3 months after treatment.

Conclusion: As GD is a new diagnostic concept more research is needed, also taking psychiatric comorbidity into consideration, to arrive at evidence-based conclusions regarding effective treatments. Considering the promising results in this small pilot study with large behavioral changes and reduced symptoms of GD, upheld at least 3 months after treatment, a larger randomized controlled study is warranted.

Clinical Trial Registration: https://www.clinicaltrials.gov/ct2/show/study/NCT05328596?term=NCT05328596&draw=2&rank=1, identifier NCT05328596.

Introduction

In 2019, gaming disorder (GD) was included as a new diagnosis in the International Classification of Diseases (ICD-11) under the section for addiction (1). Gaming disorder is manifested by impaired control over gaming, increasing priority given to gaming and continuation or escalation of gaming despite the occurrence of negative consequences. In the fifth version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), a similar construct named Internet Gaming Disorder was included among “Conditions for further studies” (2). Proposed criteria for this diagnosis include preoccupation, withdrawal, tolerance, reduced control, giving up other activities, continuing despite problems, deception, gaming to escape negative moods and risking or having lost relationships or opportunities. The suggested threshold for diagnosis is to fulfil at least five of these nine criteria in a 12-month period. As a consequence of being a newly defined disorder data on prevalence are scarce and inconsistent. Average worldwide prevalence of GD has been estimated at 1.96% with considerable differences between countries (3). Higher prevalence rates have been reported in specific groups, for example professional gamers with a prevalence rate of almost 4% (4).

There is evidence that GD often is accompanied by psychiatric comorbidity. A recent systematic review reported correlations between GD and anxiety, depression, ADHD, social phobia/anxiety, and obsessive–compulsive symptoms, with especially strong associations in adult populations (5). Regarding symptoms of ADHD, it is especially symptoms of inattention that are associated with GD (6). There are further findings that GD is associated with poor psychosocial functioning and lower performance in the academic or working spheres (79). Reduced self-satisfaction outside of playing video games, feelings of loneliness (1012), negative affectivity and disinhibition (13) is also common. Whether these psychopathologies and impairments are risk factors for GD or consequences thereof, is not known and needs to be further studied longitudinally.

Gaming disorder is more common among men (3, 7, 14, 15) and among youth and young adults (3, 16). Low levels of family cohesion have been identified as a risk factor for GD in young adults and there is also a higher probability in this group of being unmarried, unemployed, having high levels of depression and anxiety (1618), and a higher risk for suicide attempts (18) compared to individuals without GD. Several studies have shown that it is common among those with GD to use gaming to escape from negative emotions (1820).

Cognitive behavioral therapy has been suggested as the most effective treatment for GD but has mostly been tested in a young population (21). There is also a scarcity of peer reviewed clinical treatment studies that include follow-up data to conclude if treatment gains are upheld over time (22). Regarding treatments for adults there are few studies that have evaluated the efficacy of a manualized CBT program (2328) although both Wölfling et al. (25, 26) and Young (27, 28) designed their treatments for the broader concept of internet addiction (IA) including, i.e., online pornography and generalized internet addiction and not specifically for GD.

In an early CBT study that included 128 adults, decreased symptoms of IA was found and sustained at the six-month follow-up (27, 28). No control group was included. Further, the Short-term treatment of internet and computer game addiction (STICA) was tested in 143 young adults and improvements in symptoms related to IA was found compared to waitlist controls (26). In a non-randomized study, a CBT-approach for GD was compared with supportive therapy in 205 adults and reduced symptoms of GD was seen with results favoring CBT (23). Moreover, a multimodal treatment with CBT elements was tested in 40 adults and the severity of GD was decreased (24). Other CBT based psychotherapy studies has been conducted with younger subjects (12–22 years old), with 9 to 56 participants in each study, also showing positive results post treatment (2934). Only three studies had a follow up period of three or six months (29, 30, 32).

Globally, more treatment research on GD is needed. It is therefore important to develop treatment manuals designed for this group of patients and evaluate their effects. This pilot study aimed to evaluate the effects and feasibility of a recently developed CBT treatment manual designed specifically for the treatment of GD. We first hypothesize that a 15-week CBT treatment will reduce symptoms of GD in a clinical population of young adults and adults fulfilling criteria for GD. We also hypothesize that a reduction of GD symptoms will be accompanied by a reduced amount of hours spent gaming each week. Our secondary hypothesis is that there will be a concurrent decrease in symptoms of psychiatric comorbidity such as depression and anxiety. We also have a third explorative hypothesis that the participants will experience an increased quality of life and have fewer symptoms of procrastination after treatment.

Materials and methods

This is a single group pilot study with pretest, post-test and a three-month follow-up. The study included 28 participants and was conducted from February 2020 to March 2023 (from inclusion of first participant to the last three-month follow-up) in Gothenburg, Sweden, at the Clinic for Gambling Addiction and Screen Health (Mottagning för spelberoende och skärmhälsa), Department of Addiction and Dependency, Sahlgrenska University Hospital, Region Västra Götaland. The clinic is the largest of its kind in Sweden offering specialized care for patients with gambling and gaming disorder. Patients were referred to the clinic either via self-referral or by other healthcare facilities. The treatment lasted for 15 weeks. After 3 months the patients were followed up with questionnaires. A smaller amount of participants were also followed-up after 6 months.

Subject recruitment and screening

The participants were consecutively recruited from the treatment-seeking population at the clinic. The initial assessment was conducted either as a videoconference or on site and included an anamnestic interview, a semi-structured diagnostic interview regarding symptoms of GD, screening for other psychiatric disorders, assessment of health, lifestyle, and psychosocial resources. After this assessment, made by a psychologist, a social worker or a nurse, participants were offered to enter the treatment program. All participants signed a consent form.

To be included in the study participants needed to fulfil the diagnostic criteria for Internet Gaming Disorder according to DSM-5 (≥ 5 criteria). Participants had to be able to read and write Swedish fluently and have turned 15 years old. Participants were excluded if they had somatic or psychiatric conditions that contraindicated treatment or severely hindered treatment participation e. g. ongoing psychotic, manic or hypomanic episode, severe depression (PHQ 20–27 p) or neurodevelopmental disorder (e.g., ADHD or autism) with low functional status evident by for example being in need of help with many activities of daily living, were currently in another psychological treatment with similar content as the one offered in the study or had started, or had ended or adjusted a medication for a psychiatric condition during the last 3 weeks. The study was approved by the regional ethics committee of the University of Gothenburg and complied with the guidelines of the Declaration of Helsinki (Dnr: 2020-07144).

The CBT-treatment for gaming disorder

There exists no gold-standard treatment of behavioral addictions. The Gothenburg Treatment for Gaming Disorder (GOT-TO-GO) is designed to focus on gaming specific problems. The treatment has been developed at the clinic and consists of CBT-techniques such as stimulus control, cognitive restructuring and relapse prevention commonly known from other treatment programs for GD (24, 32), addictive behaviors (25, 26, 32, 3538) and substance use disorders (3941) including behavioral self-control training (42). In addition, elements from motivational interviewing (MI) (43) are used, especially in the initial stages of treatment to strengthen the motives for behavioral change, as this method has been shown to be effective in supporting other types of behavioral change (44, 45). Motivational interviewing does probably not have a significant effect as a standalone intervention (46). However, using MI-exercises such as “decisional balance” serves as a useful framework to chart both positive and negative aspects of gaming, thereby laying groundwork for the formulation of individualized treatment goals.

The manual tested in this study was delivered with one session per week comprising 15 weeks. Additional support regarding psychosocial resources or health and lifestyle factors were offered if such a need was identified. The added support consisted of a few optional sessions (described more in detail below), in addition to the CBT-treatment.

To closely follow the patients’ progression during treatment, they answered self-report questionnaires (dependent measures, see below) throughout the study (at baseline, mid-treatment, end of treatment and at follow-up). Starting at the first session, and continuing throughout the treatment, patients were also encouraged to keep track of their gaming activity via a weekly gaming diary.

The GOT-TO-GO treatment is divided in three phases: Initial stages, new skills and relapse prevention (for an overview see Table 1). Phase 1: In the initial phase individual goals for the treatment are formulated. Motivational techniques are also used to strengthen the patient’s commitment to change. Goals are formulated both regarding gaming activity (what amount and type of gaming activity the patient wants to retain at end of treatment) and other changes the patient wants to make during treatment (for example to increase weekly exercise or to increase social activities outside gaming). Self-monitoring of gaming is introduced. Phase 2: Sessions follow with a focus on learning new skills to control gaming activity and to initiate other activities. The patients learn to identify their individual triggers for gaming, and strategies for stimulus control are implemented (for example uninstalling programs, moving the computer to another room, or blocking internet access for parts of the day). Much attention is also devoted to the introduction of new activities (behavioral activation), chosen individually to match the interests and goals of each patient, to fill some of the time otherwise devoted to gaming. Techniques for handling difficult feelings and unhelpful thoughts related to gaming are also introduced and practiced, as well as time-management and problem-solving skills. Phase 3: At the final stages a plan is formulated to maintain the changes made during treatment and how to get back on track if a relapse occurs. A summary is made of the most helpful techniques learned during treatment, the patients identify situations where they expect it would be especially difficult to maintain their changes and formulate strategies to tackle this (both proactive to stay on track and reactive to get back on track if they relapse). Follow up: After treatment is completed, the patients are contacted by phone for a follow-up after three and six months. As part of the follow-up the patients also fill out self-report questionnaires. If needed, two booster sessions are offered to analyze problematic situations that have occurred and to revise the relapse prevention plan. Optional modules: In addition to the above-mentioned sessions, there are also optional modules. Based on the intake assessment an individual plan for optional modules is made. An individual patient can take part in none, some, or all of these. The optional modules consist of (a) 1–3 family sessions where family members and/or significant others meet with the patient and, with assistance from a social worker, make plans on how to work together to reach the patient’s treatment goals. This has been added as familial conflicts about gaming and lack of consensus about treatment goals might hinder change (47), and conversely that higher levels of family cohesion seem to be a protective factor against GD (16), (b) 1–3 additional sessions for support regarding psychosocial resources, for example to establish contact with other societal support systems, (c) 1–3 additional sessions for support regarding health and lifestyle factors, for example to initiate physical exercise or to cut down on alcohol use, (d) 1 additional session for support on how to plan and conduct home-work assignments throughout treatment.

TABLE 1
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Table 1. Content of the CBT-treatment for gaming disorder together with measure points.

The GOT-TO-GO manual is based on general techniques from other CBT-treatments for substance use disorders and behavioral addictions. Therefore, several parts are similar to other CBT-treatments [for example the method developed by Wölfling et al. (26)]. However, our manual also differs in many ways from other treatments for behavioral addictions and specifically gaming disorder. One essential difference is that the manual, unlike many other approaches, is specifically developed for gaming disorder. More specific differences are that strategies to control and limit gaming is implemented without a period of total abstinence, the manual consists of fewer sessions [15 sessions in total compared with 23 sessions described by Wölfling et al. (26)], and in the gaming diary, time spent gaming is separated from other types of time spent online. The intervention has been developed with a population with considerable psychiatric co-morbidity in mind. Handouts for patients have been made as simple as possible and a flexible system with additional sessions to meet individual needs has been designed. We also include family sessions to help the family support the patient and offer support to activate a professional network around the patient.

Variables and measures

Primary outcome measures

Gaming addiction identification test

The GAIT was our main outcome measure. GAIT is the only screening tool for GD developed and validated in a Swedish population. It consists of 17 questions regarding gaming that cover all the DSM-5 diagnostic criteria for Internet gaming disorder. The questions concern all digital games including games on computer, mobiles or TV, both gaming with others and alone (48). Suggested cut-off for GD is at least five questions being endorsed as “completely agree.” For this study a version of the questionnaire has been used that covers gaming during the past 30 days. The 30-day version was used due to our repeated measure design with the aim to detect a change in symptoms of gaming disorder over the course of the 15-week treatment, as well as during follow-up at intervals of only 3 months. GAIT has very good internal consistency (Cronbach’s alpha = 0.95).

Gaming disorder – time line follow back

We used a timeline follow back measure as our second main outcome measure. This type of measure was originally developed to track alcohol-consumption (49) but has been adapted for this study to track behaviors relevant to GD. The GD-TLFB is a diary where frequency and duration of weekly gaming can be tracked as well as other time spent online and time spent on screen-free activities. The gaming diary serves as a valuable complement to the symptom measures. Although the aim of treatment is to alleviate the negative consequences of gaming (the symptoms) and not time spent gaming per se, still, decreasing time spent gaming is a necessary step to reach that goal. Aside from being used as an outcome measure, the gaming diary also serves as an important clinical tool for self-monitoring.

Secondary measures

The Patient Health Questionnaire (PHQ-9) consists of nine items screening for symptoms of depression during the last 2 weeks. PHQ-9 is developed according to the diagnostic criteria in DSM-4 and the total score can be used to assess severity of depressive symptoms. Based on the total score the level of severity is classified as none (0–4), mild (5–9), moderate (10–14), moderately severe (15–19) or severe (20–27) depression. PHQ-9 has been shown to have high validity in detecting severity of depression (50).

The Generalized Anxiety Disorder Assessment (GAD-7) was developed as an instrument to measure severity of symptoms of anxiety. It is a seven-item questionnaire screening for symptoms during the last 2 weeks. The total score is 21, and the scores indicate minimal (0–4), mild (5–9), moderate (10–14) or severe (15–21) anxiety (51).

Exploratory measures

The Brunnsviken Brief Quality of life scale (BBQ) measures an individual’s subjective quality of life. It is divided into six different life areas that are rated individually regarding perceived importance and satisfaction. The maximum score is 96 with higher scores indicating higher levels of quality of life, and scores below 52 being associated with clinical samples (52).

The Pure Procrastination Scale (PPS) identifies the occurrence and severity of procrastination. It consists of 12 items rated on a 1–5 point Likert scale with higher scores indicating higher levels of procrastination (53).

Subject demographics

We also collected demographic data about the participants including age, sex, educational level, living situation and current occupation. Levels of alcohol and drug use were measured with the AUDIT (54) and DUDIT (55).

The Alcohol Use Disorders Identification Test (AUDIT) is a screening tool for alcohol related problems and identifies individuals with harmful use of alcohol. It consists of 10 items divided into three areas: alcohol consumption, symptoms of dependence and negative consequences of alcohol consumption. The maximum score is 40, with a cut-off score of 6 for women and 8 for men indicating hazardous or harmful drinking (54).

Drug Use Disorders Identification Test (DUDIT) is a screening tool for problematic use of illicit drugs. Like AUDIT, it is a 10-item instrument with a maximum score of 40. The questions are categorized in three areas, drug use, dependence symptoms and negative consequences of drug use. DUDIT scores of 1 or more for women and 3 or more for men indicate problematic drug use (55).

Data analysis

All analyses were conducted in IMB SPSS 28.0.1.1. Out of the 28 participants 12 were treated individually and the rest in group format. In the analyses, irrespective of having received the treatment via group or individual sessions, data from all participants have been included. The primary outcome variables were symptoms of GD measured by the GAIT and the four measures included in the gaming diary. Secondary measures included the PHQ-9, the GAD-7, and the exploratory measures were the BBQ and the PPS. The gaming diary consisted of nine repeated measures from the start of treatment to the last session of treatment. The GAIT, as well as the PHQ-9 and GAD-7 were also given at repeated intervals, at baseline, mid-treatment, termination of treatment, and 3-months follow-up. The BBQ and PPS instead were repeated at baseline, termination, and 3-months follow-up. For the gaming diary a total of 41% of data points were missing, ranging between 7% to at most 50% at specific timepoints and measures. For the GAIT, PHQ-9, and GAD-7 a total of 33% of data were missing, ranging from 4% at baseline to 57% at the 3-month follow-up. For the BBQ a total of 26% of data was missing, ranging from 4% at baseline and 57% at three-month follow-up. For the PPS a total of 42% of data was missing, ranging from 29% at baseline and 61% at 3-month follow-up.

Mixed-effects models fitted with maximum likelihood estimation were used to estimate individual changes over time during treatment (gaming diary) and from baseline to follow-up (GAIT, PHQ-9, GAD-7, BBQ, and PPS). Mixed effects models were used as they handle missing data and correlation between repeated measurements better than a classical repeated measures ANOVA (56, 57). Further, as the mixed model uses all available data points it is possible to do an intention-to-treat analysis, including all participants in the analysis.

For the primary outcome measure GAIT, a basic model with a fixed slope for time was created. Time was coded as 0–3 with 0 being baseline and 3 being 3-month follow-up. To account for possible non-linear effects a quadratic effect of time x time was tested, found non-significant and was therefore discarded. A random intercept and random slope for time was tested but did not improve the model according to a likelihood ratio test and were thus discarded. A heterogeneous first-order autoregressive covariance pattern was used for the repeated measures and was significant, p < 0.001.

Model building was approached in the same way for the secondary outcome PHQ-9, and time was similarly coded here. The quadratic effect of time x time was non-significant and discarded. A random intercept and random slope for time improved model fit according to a likelihood ratio test p < 0.05 and were retained. A diagonal covariance pattern was used for the repeated measures as the model did not otherwise converge. Unstructured covariance type was used for the random effects.

For the GAD-7 time was similarly coded. The quadratic term of time x time was non-significant and discarded. The random intercept and random slope for time did not improve model fit according to a likelihood ratio test and were discarded. A heterogeneous first-order autoregressive covariance pattern was used for the repeated measures and was significant, p < 0.001.

For the BBQ time was coded 0–2, with 0 being baseline, and 2 being three-month follow-up. The quadratic term of time x time was non-significant and discarded. When the random intercept and random slope for time was added the model failed to converge, and the model with random intercept were not an improvement according to a likelihood ratio test. The random effects were thus discarded. A heterogeneous first-order autoregressive covariance pattern was used for the repeated measures and was significant, p < 0.001.

For the PPS time was similarly coded. The quadratic term of time x time was non-significant and discarded. When the random intercept and random slope for time was added the model failed to converge. A model with diagonal covariance pattern and random intercept did converge and was a better model according to a likelihood ratio test. However, a model without random effects using a heterogeneous first-order autoregressive covariance pattern (p < 0.001) proved to have similar fit and was chosen as it was a simpler model.

As the 6 months follow-up was not conducted for all participants (n = 9 out of 28, n = 8 for the GAD-7) this timepoint was not included in the above models. The means and standard deviations for these participants are however presented for descriptive purposes.

For the primary outcome hours gaming/week a basic model with a fixed slope for time was created. Time was coded as 0–8 with 0 being diary entry pre-treatment and 8 the final entry during treatment. A quadratic fixed effect of time x time was tested to account for possible non-linearity. This effect was significant, p < 0.05 and was retained. A random intercept improved model fit according to a likelihood ratio test, p < 0.001 and was retained. A heterogeneous first-order autoregressive covariance pattern was used for the repeated effects and was significant, p < 0.001.

For days gaming/week model building was approached in the same way and time was coded similarly. The quadratic effect of time x time was non-significant and was discarded. A random intercept and random slope for time significantly improved model fit (likelihood ratio test, p < 0.001) and were retained. A diagonal covariance pattern was used for the repeated measures as the model did not otherwise converge. Unstructured covariance type was used for the random effects.

For non-gaming screen time, time was coded similarly. The quadratic effect was non-significant and discarded. A random intercept and random slope for time produced a model with better fit (likelihood ratio test, p < 0.001) and these effects were retained. A diagonal covariance pattern was used for the repeated measures as the model did not otherwise converge. Unstructured covariance type was used for the random effects.

For non-screen leisure time, time was coded in the same way. The quadratic effect was non-significant and discarded. A random intercept and random slope for time significantly improved model fit (likelihood ratio test, p < 0.001) and these effects were retained. A heterogeneous first-order autoregressive covariance pattern was used for the repeated effects and was significant, p < 0.05. Unstructured covariance type was used for the random effects.

Estimated means of variables were calculated for all time points in the mixed-models that yielded significant effects. Estimated means of non-significant models are not reported.

Cohen’s d effect sizes were calculated for significant effects (58). For the mixed-models, Cohen’s d was calculated between baseline mean and mean at the final time-point in the series using the model estimated means together with the observed standard deviation at baseline (59). Confidence intervals of within group effect sizes were calculated using Pearson correlations of observed values between baseline and the final time-point.

In the participants section, harmful alcohol use and problematic drug use was based on cut-off values for AUDIT (≥ 8 for men, ≥ 6 for women) and DUDIT (≥ 3 for men, ≥ 1 for women) scores (54, 55).

Results

Subject demographics

There were 28 participants included in this study, with an average age of 27.7 (SD 7.3) years. Of these, there was only one woman (3.6%), and the rest were men. The most preferred games were Massively multiplayer online role-playing games (MMORPG), Multiplayer online battle arena (MOBA) and First-person shooter games (FPS). In the sample, 71.5% had a high school education or higher. The majority 60.8% were employed or studying, 17.9% were on sick leave, 14.3% were unemployed and 7.2% had another occupation or some combination of the above. The most common living situation was living together with relatives/parents/friends (44.4%), followed by living alone (22.2%). Of the participants, 26.9% used nicotine in some form. Regarding alcohol and illicit drugs, 11.1% of participants had a harmful alcohol use based on AUDIT scores, and 11.1% a problematic drug use based on DUDIT scores. See Table 2 for a full list of subject demographics.

TABLE 2
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Table 2. Subject demographics.

Of the 28 participants, 24 completed the 15 week GOT-TO-GO treatment resulting in a dropout rate at 14% which is below the normal rates (19–51%) in psychiatric health care (60).

Primary outcomes

The model estimates for the primary outcome of GD symptoms measured by the GAIT can be found in Table 3 along with confidence intervals, p-value and effect size. The model intercept of 42.52 is the estimated baseline score for all participants. The significant effect of time (p < 0.001) of −9.62 means that from each step between baseline to 3-month follow-up the GAIT score is reduced by X*9.62 points (baseline X = 0, mid X = 1, post X = 2, three-months X = 3). This means that symptoms of GD decreased over time. This is illustrated in Figure 1, where model estimated means are plotted over time and compared to observed means with standard deviations. The observed mean for the limited number of 6-months follow-ups is also presented in Figure 1 for descriptive purposes. The effect size of change between baseline to 3-month follow-up was large, d = 4.03.

TABLE 3
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Table 3. Model estimates of gaming behaviors, including confidence intervals, p-values and effect sizes.

FIGURE 1
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Figure 1. Observed means from baseline to 6-month follow-up, and estimated means from baseline to 3-months follow-up for the GAIT. aA significant effect of time, p < 0.001 was found in the model.

In Table 3 the model estimates together with p-values, confidence intervals and effect sizes for the various measures of gaming behavior derived from the gaming diary are reported. Participants were gaming at a model estimated average of 45.65 h/week at baseline. A significant effect of time (pre-treatment to final measurement) (p < 0.001) of −9.62 and time x time (p < 0.001) of 0.65 meant that hours/week were reduced during treatment, but the rate of change slowed down each week and even increased somewhat at the end of treatment (each step from baseline the score is reduced by X*8.33 – X2*0.65). The model estimated hours/week at the final measurement was an average of 20.61 h/week. The effect size of the reduction from pre-treatment to the final measurement was medium sized, d = 0.63. There was also a significant effect of time (p < 0.05) of −0.73 regarding non-gaming screen hours/week. This means they were reduced linearly from a model estimated average of 25.87 h pre-treatment to 20.0 h at the final measurement. The effect size was small, d = 0.36. Non-gaming leisure hours instead significantly increased linearly over time (p < 0.001) with 1.41 for each measurement point during treatment. The model estimated an average of 16.6 h non-gaming leisure time at baseline, and 27.89 h at the final measurement. This was a medium sized effect, d = 0.75.

No significant change over time (p = 0.164) was found regarding the number of days/week participants were gaming. See Table 4 for observed means and standard deviations, and model estimated means for the measures in the gaming diary.

TABLE 4
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Table 4. Time line follow back gaming diary.

Secondary and exploratory outcomes

Symptoms of depression were found to significantly (p = 0.001) decrease linearly over time, from baseline to 3-month follow-up with a rate of −2.44 points on the PHQ-9 for each timepoint (baseline, mid-treatment, post-treatment, 3-months). The model estimated mean at baseline was 10.64 and this was reduced to a model estimated mean at 3-month follow-up of 3.33. The effect size of change was large, d = 0.98. Anxiety symptoms measured by the GAD-7 also decreased linearly over time (p < 0.001) with an estimated rate of −1.42 from an estimated baseline score of 7.21 to 3.09 at 3-month follow-up. This was a large effect, d = 0.80.

Procrastination, measured by the PPS, also decreased significantly over time (p < 0.001) by −5.58 for each timepoint (baseline, post-treatment, 3-months) from a model estimated 42.25 at baseline to 31.1 at 3-month follow-up, which was a large effect, d = 0.99. There was no significant effect of time on quality of life measured by the BBQ from baseline to 3-month follow-up, p = 0.060.

Model estimates, p-values, confidence intervals and effect sizes for the PHQ-9, GAD-7, BBQ, and PPS models can be found in Table 5. Observed means and standard deviations as well as model estimated means can be found in Table 6. Observed means for the limited number of 6-month follow-ups are for descriptive purposes also presented in Table 6.

TABLE 5
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Table 5. Model estimates of non-gaming behaviors secondary outcomes, including confidence intervals, p-values and effect sizes.

TABLE 6
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Table 6. Means, standard deviations, and model estimated means for non-gaming behavior secondary outcomes.

Discussion

This was an uncontrolled pilot study intended to evaluate the feasibility of a newly developed manualized CBT treatment for patients diagnosed with GD. The 28 participants included in the study were followed from baseline to 3-months post treatment. We investigated symptoms of GD, sociodemographic factors, alcohol and drug use, depression and anxiety, quality of life and procrastination.

Sociodemographic characteristics

We notice both differences and similarities regarding sociodemographic characteristics when comparing the patients in our study with populations in earlier studies. The mean age in our sample was 28, meaning that we reached an older group than most previous clinical studies where the age range has been between 12 to 22 years of age (5, 2934). However, both the age range and the high education level seen in our study is similar to other IA-studies with adult patients (26, 28).

In our study, only one woman chose to participate. The prevalence of GD is estimated to be 2.5 times higher among men than women, and therefore it is expected that more men than women will seek treatment. However, the proportion of women in our study and other treatment studies for GD (23, 24) are still much lower than could be expected based on prevalence. In this aspect, GD differs from other psychiatric conditions where women usually are overrepresented as treatment-seekers (61). Still, we believe it is important to continue including women in future treatment studies, and also make active efforts to reach more women with GD.

The association between GD and substance use has been investigated, but findings so far are mixed. We found that a small proportion of our patients had a problematic intake of alcohol or other drugs, to a comparable extent with the Wölfling et al. (26) study. Other studies have for example shown a positive correlation between severity of GD and frequency of substance use (6365). Studies have also shown that those who play under the influence of for example stimulants, Ecstasy/MDMA, sedatives or amphetamines spend more time gaming than non-substance users (62) and that high alcohol consumption is an antecedent to gaming disorder (66). On the other hand, it has also been reported that a heavy investment in gaming may lead to a reduction in alcohol use (67) or that no association between alcohol and gaming disorder could be detected (63). Considering the findings that some treatment seekers with GD also have a problematic intake of alcohol or other drugs, together with the mixed research findings so far regarding associations between GD and substance use, we believe that it is important to regularly screen for possible co-morbidities with SUD in future treatment studies. Thereby, we can increase our knowledge on how substance use and SUD might affect treatment results, and if changes regarding gaming also are associated with changes in substance use.

Changes during treatment

We found a significant reduction in symptoms of GD between baseline measurements and the 3-months follow-up, in total a decrease by 70% based on measures with the GAIT. Similarly, hours spent gaming per week, measured with the GD-TLFB, decreased by 62% during treatment, which corresponds to 32 h less gaming per week. Time spent gaming after treatment was on average 19.5 h per week which is well within the normal range according to Swedish Media Council (68). We want to emphasize that the aim of the treatment was not total abstinence from gaming or other internet activities but simply to gain control over gaming habits. With the gaming diary we also wanted to measure changes in non-gaming screen time, to make sure that time spent gaming not only transitioned into other types of screen-time. Instead, the gaming diary showed that the decrease in time spent gaming also was accompanied by a small decrease in other types of screen time. The patients also more than doubled their amount of screen-free leisure time. It is difficult to compare results from different studies as there are no gold-standard instruments for measuring GD, and many different instruments have been used in previous studies (69). With this caveat in mind, we observe that in our study, as well as in earlier studies regarding adults with IA (26, 28) and GD (23, 24), we see substantial changes in symptoms after treatment compared to baseline. This also holds for changes in hours spent online in our as well as in other studies (26, 28). In summary, this shows promise for using a CBT approach for treating GD.

Our secondary measures focused on anxiety, depression, quality of life, and procrastination. For these variables we saw changes in the expected direction, although the change in quality of life did not reach statistical significance. We argue that all these aspects are important to take into account when evaluating treatments for GD. By measuring for example quality of life we address a broader definition of health than simply the absence of symptoms, and capture additional aspects highly relevant to GD. Lower quality of life has been shown to be associated to GD, and also differentiating highly engaged gamers from those with problematic gaming (70, 71). The complex interplay between these factors is also illustrated by findings that levels of anxiety and depression mediate the relationship between GD and quality of life (72).

We also saw a significant reduction of symptoms of procrastination, measured by the PPS (53) after treatment, although the levels were still high. The decision to include strategies to identify and handle procrastination in our manual was based both on clinical observations, and earlier findings that symptoms of procrastination was associated with clinical severity of internet gaming disorder (73). Similarly, in a prevention program for adolescents with at risk for GD, a reduction of symptoms of GD was accompanied by a decrease in procrastination (74). The association between procrastination and GD is further supported by findings that lower levels of procrastination predict spontaneous remission of GD (75). Based on this we suggest that procrastination could be a relevant factor to take into consideration in treatment strategies for GD.

Limitations, implications, future research, and conclusions

Our study had some clear limitations but also strengths. There are a number of limitations in the dataset from this study: the sample size is small, there are missing data, there is no pre-treatment measurement for the primary outcome and a number of secondary outcomes, and repeated measurements have been given at variable time points (i.e., the gaming diary was not given every week during treatment but instead at specific sessions with varying amounts of time in between). The choice to collect the gaming diary more seldom than every week was made to minimize missing data. Still, a substantial amount of data was missing. In the coming randomized controlled trial (RCT) we will amend this by focusing more on collecting diaries on even fewer occasions during treatment, thereby being able to focus more on making sure that diaries on these chosen weeks will be registered. The use of weekly diaries will still be part of the treatment, but our experiences so far indicate that, for a considerable part of the intended study population, remembering or wanting to complete these daily or weekly throughout the whole treatment period poses a challenge. Even though statistical methods (maximum likelihood estimation) have been employed to reduce the problem of missing data, the results of this pilot study should be interpreted with care. The single group design also limits the conclusions. These limitations will be corrected in a randomized controlled treatment study with follow-up at 3, 6, 12, 18 and 24 months (ClinicalTrials.gov NCT05328596).

There is a lack of treatment options and insufficient evidence regarding effective treatment of GD. This is the first treatment manual for GD, developed and studied in Sweden, closely evaluated with standardized measures and one of the few treatments so far developed specifically for GD. Moreover, our study participants have undergone a careful diagnostic assessment. This study is also highly clinically relevant as the participants are treatment seeking patients in regular care. Moreover, the patients have completed a follow up assessment 3 months after the treatment ended, which gives us a longitudinal indication of sustained effects. This is a strength since follow-up data after treatment is scarce (3, 21). Findings about the stability of GD over time are somewhat mixed. From studies to date it seems that a proportion of people with GD spontaneously recover (76) but a sizable amount remains that still fulfil the diagnosis at least one year later or more (66, 75). We also consider it a strength that we offer a flexible treatment, with additional sessions to add if needed.

To regain control over one’s gaming behavior is challenging for all individuals and even harder for those with comorbid psychiatric disorders. We noted that almost 100% of the participants in our study had symptoms of psychiatric comorbidity with mood disorders as the most common one. A vast majority were men, not seldom isolated using the game to escape from negative thoughts and emotions.

Our CBT treatment, specifically designed to treat patients with GD, showed promising results with reduced symptoms of GD, upheld at least 3-months after treatment, accompanied by decreased time spent gaming almost equivalent to a normal work week. We further observed that the treatment was feasible to deliver as most patients stayed in treatment, and that the treatment was possible to implement as a part of regular care at the treatment center.

In conclusion, there is insufficient evidence regarding effective treatments for GD. Based on our promising preliminary pilot findings, we will conduct a RCT. For the upcoming RCT the manual will be shortened, giving increased possibilities to add sessions based on individual needs. We believe there is a need for a flexible treatment specifically designed for individuals with GD with considerable psychiatric comorbidity, to help them improve their quality of life and regain control over their gaming.

Data availability statement

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.

Ethics statement

The studies involving human participants were reviewed and approved by Swedish Ethical Review Authority. Written informed consent from the participants' legal guardian/next of kin was not required to participate in this study in accordance with the national legislation and the institutional requirements.

Author contributions

AH had the main responsibility of the writing of the manuscript also contributed with specific knowledge in gaming addicted patients and the main idea for the manuscript. MM made all the statistical analyses and responsible for the result section. EA was responsible for the informed consent form to collect and keep track of the data and Method section. SL, JM, and AL developed the GOT-TO-GO manual and worked as the psychologists treating the patients in the study, reading the manuscript, and helped in writing the Method section. AS was a senior researcher of the work and the Principal investigator for this research, and supervised the writing of the whole manuscript throughout the research process. All authors contributed to the article and approved the submitted version.

Funding

This study was supported by Svenska Spel’s Independent Research Council, grant no FO2021-0007.

Acknowledgments

The authors thank Svenska Spel’s Independent Research Council for funding this study. They thank the patients in this study for their helpful feedback and comments about the GOT-TO-GO manual. They also thank all the staff involved at the Clinic for gambling addiction and screen health.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

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Keywords: adolescents, young adults, adults, treatment, CBT, gaming disorder, pilot

Citation: Hofstedt A, Mide M, Arvidson E, Ljung S, Mattiasson J, Lindskog A and Söderpalm-Gordh A (2023) Pilot data findings from the Gothenburg treatment for gaming disorder: a cognitive behavioral treatment manual. Front. Psychiatry. 14:1162492. doi: 10.3389/fpsyt.2023.1162492

Received: 09 February 2023; Accepted: 08 May 2023;
Published: 06 June 2023.

Edited by:

Victoria Gomez-Murcia, University of Murcia, Spain

Reviewed by:

Angelica Beatriz Ortiz De Gortari, University of Bergen, Norway
Yuqing Zhang, The Second Affiliated Hospital of Chongqing Medical University, China

Copyright © 2023 Hofstedt, Mide, Arvidson, Ljung, Mattiasson, Lindskog and Söderpalm-Gordh. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Annika Hofstedt, annika.hofstedt@vgregion.se

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